Structural & functional analysis revealed that the extracellular #chaperone #clusterin functions through two tails in preventing protein aggregation. ❕Paper: www.nature.com/articles/s41... ❕Press Release: www.biochem.mpg.de/structure-of... #Alzheimers @natsmb.nature.com @pyustecheca.bsky.social

Curious about the structure and functional analysis of one of the most abundant and enigmatic extracellular #chaperones and one of the highest genetic risk factor for developing late onset #Alzheimer’s disease? Check out our paper on Clusterin/ApoJ! #proteostasis #apolipoprotein rdcu.be/ezRLv

New online: Structural analyses define the molecular basis of clusterin chaperone function

Exicted to share our latest review in @narjournal.bsky.social on how the ribosome coordinates mRNA decay with a focus on structural advances in the field. #ribosome #mRNAdecay #translation