✨ Blinking #nanobodies that work for single-molecule localization 🔬 Our new preprint shows that the self-blinking dye JF635b restores robust, buffer-free blinking in #nanobodies, enabling reliable #dSTORM, #MINFLUX, and more, without chemical-switching buffers. Opening new possibilities for #ExM!

🧬 New paper out! Thrilled to contribute to our study on CaV1.3 channel clusters in cardiac myocytes using DNA-PAINT (4 nm loc. precision!) revealing flexible (not rigid) cluster organization. 👏 Great work by Niko Schwenzer, @samratb.bsky.social & team! 👉 www.sciencedirect.com/science/arti...

This #Halloween 🦙🧛‍♂️ Alpacula brewed up #SMLM treat! No more horror stories of no blinking & black holes ⚫️🔬Our single-domain anti-BOOdies 👻 #FluoTags and #SmartSecondaries now glow with self-blinking JF635b✨, delivering frightfully precise and simple #dSTORM imaging. 👉 bit.ly/4ffIkdB

We present a versatile microfluidics platform that makes multiplexed super-resolution imaging more accessible, reproducible, and high-throughput. 👉 BioRxiv: www.biorxiv.org/content/10.1... #SuperResolution #DNApaint #Microfluidics #SMLM #OpenScience #multiplexing

Check the live stream of the Göttingen Expansion Forum 2025 if you're interested! I think the link changes every day will try to update. Program is here (pdf link): www.rizzoli-lab.de/wp-content/u...

🚨 New preprint update! 🚨 We introduce Confocal MIET-PAINT — extending our 3D nanoscopy method with: ✨ High multiplexing capacity ✨ Isotropic nanometer-scale resolution (lateral + axial) ✨ Compatibility with custom & commercial confocal SMLM equipped with FLIM www.biorxiv.org/content/10.1...

To anyone who were excited for the release of SUM-PAINT, we now published a detailed protocol on to how replicate it in your hands! Check it out here: doi.org/10.1016/j.xp...

Our invited speaker list is now online and we hope that your are as excited as we are! 🤗

Thrilled to share our latest review paper, "Advanced Fluorescence Lifetime-Enhanced Multiplexed Nanoscopy of Cells", co-authored with @samratb.bsky.social, now published in Methods in Microscopy! 🚀✨ Check it out here: www.degruyter.com/document/doi... #FLIM #SMLM #FLPAINT #FLSMLM #MIETPAINT