Kelsey Person
@kelseyperson.bsky.social
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UMN Neuro PhD Candidate🧠
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Kelsey Person
Sanford Burnham Prebys
8 days ago
Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University report in Nature that “biased modulators” can target GPCRs more precisely—expanding potential drug targets and reducing side effects.
www.nature.com/articles/s41...
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Kelsey Person
Science X / Phys.org
9 days ago
Newly designed molecules acting as "molecular glues" and "bumpers" can selectively rewire GPCR signaling, offering a pathway to more precise and potentially safer medicines.
doi.org/g98xfp
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'Molecular glues' and 'bumpers' offer new hope for precision medicines
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools—opening the door to a new generation of safer, smarter medicines.
https://medicalxpress.com/news/2025-11-molecular-bumpers-precision-medicines.html?utm_source=bsky.app&utm_medium=social&utm_campaign=v2
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Kelsey Person
Nature
14 days ago
Nature research paper: Designing allosteric modulators to change GPCR G protein subtype selectivity
go.nature.com/49jaBQS
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Designing allosteric modulators to change GPCR G protein subtype selectivity - Nature
Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching receptor subtype preference.
https://go.nature.com/49jaBQS
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Excited to share that my co–first author paper has been accepted in
@nature.com
🎉 We show that small molecules binding at the GPCR-transducer interface can predictably switch G protein selectivity - paving the way for structure-guided, pathway-selective drug design.
www.nature.com/articles/s41...
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Designing allosteric modulators to change GPCR G protein subtype selectivity - Nature
Studies of the G-protein-coupled receptor NTSR1 show that the G protein selectivity of this receptor can be modified by small molecules, enabling the design of drugs that work by switching receptor su...
https://www.nature.com/articles/s41586-025-09643-2
20 days ago
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Kelsey Person
Black In Neuro
6 months ago
🎉BIN is turning 5️⃣—and going in-person for Black In Neuro Conference 2025 in Washington, DC 🧠✨ 🗓️ It's time to save the date: September 10-12, 2025 Let’s celebrate 5 years of community, connection, and Black excellence in neuroscience! More details to come soon!! 🤗
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Kelsey Person
SmithLabUMBC
8 months ago
Our 28-yr U-RISE/MARC NIH grant that has served over 500 students and made us one of the top institutions producing African American students who go on to receive MD/PhDs in the United States was just cancelled yesterday. What a unnecessary and tragic end to such an impactful program...
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Excited to share this! Check it out!👇🏾👇🏾
add a skeleton here at some point
12 months ago
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Kelsey Person
Black In Neuro
12 months ago
#BlackInNeuro
Starter Pack v1! Let us know if we missed you.
#BlackInSTEM
#Neuroscience
🧪
go.bsky.app/F8PpdPe
add a skeleton here at some point
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