A poster, a conversation, and a cross-Atlantic collaboration where bioinformatics meets neuroscience to uncover new insights into Alzheimer’s disease 🌍🧠 www.ebi.ac.uk/about/news/t... #Alzheimers 🖥️🧬

Many thanks to the generous support of my mentors @jgrutzendler.bsky.social , Angus Nairn, and many amazing collaborators @iguaracy.bsky.social @mslob95 and funding from the NIH, @embl.org, @brightfocus.bsky.social, @alzassociation.bsky.social, Yale/NIDA Neuroproteomics Center, and Yale ADRC.

We present SELPHI 2.0 a machine learning model integrating >40 sequence, omics and structural features to predict kinase-substrate interactions between 420 kinases and 240K phosphosites and improve interpretation of global phosphoproteomics data www.sciencedirect.com/science/arti...

Organoids have incredible potential in drug discovery and disease modelling. In this Scientific Computing World interview, @iguaracy.bsky.social discusses organoid construction, nanobots, and how bioinformatics is transforming biomedical research. www.scientific-computing.com/article/usin...