The @jimboonya.bsky.social lab at Fred Hutch found the use of sirolimus #GVHD prophylaxis in allo HCT recipients was linked to a higher risk for RSV infection, whereas higher serum neutralizing antibody levels were linked to a lower risk in the first 100 days post-transplant. https://wb.md/3Zokzua

Getting asked about how academics can continue to do science & inspire trainees even in the midst of a continued (escalated) assault on science, reason, truth, & human rights. I don’t have great answers. I would love to hear from mentors about advice they’re giving to trainees/ colleagues.

A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging Naked mole rats get much older than closely related mamals of a similar size. cGAS mutations may have an important role in this. www.science.org/doi/... 1/9

hey bluesky 👋 visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

🥳 Very grateful for the support of the ERC Starting Grant for my newly established lab! We will study how transposable elements contribute to mammalian embryonic development. We will have positions available next year. Stay tuned!

Super interesting deep dive into US excess mortality. We're doing better than we were in 1980 but a *lot* worse than every other high-income country. jamanetwork.com/journals/jam...

Pretty surreal to see my artwork on the cover of Nature Genetics! Big congrats to @julianeg.bsky.social, @stemundi.bsky.social and the others, and thank you Juliane for letting me help bring your research to life visually. www.nature.com/ng/volumes/5...

⚠️ Discovery of a new mode of viral transmission: Deltaviruses spread through a viral Trojan Horse ! These viral satellites that do not encode their own glycoproteins, are in fact physically encapsulated within their helper virus particles! www.biorxiv.org/content/10.1... A thread 1/14

I got hit by some rather sudden and extreme financial hardship so if anyone is in need of remote wetlab contract research, strictly BSL1, do let me know. Currently scrambling for gigs. Plant, Bacterial, Archaeal Non-model Bioeng Custom Lab Hardware Turn Key Genetic Design Please repost for reach 💚

I always like to reference this comparison chart that @rrbehringer.bsky.social made awhile back. Hope it helps put things in perspective! -KT

“One young man sobbed when a guard pushed him to the floor. He said, ‘I’m not a gang member. I’m gay. I’m a barber.’ I believed him. *** He “began to whimper,” as his head was roughly shaved, “folding his hands in prayer as his hair fell.” He “asked for his mother & cried as he was slapped again.”

Pet peeve: I hate how often ppl claim “all the researchers will just move to Europe/Canada!” You vastly under-estimate how little money there is there vs the USA- and unless that changes ASAP this loss is just going to decimate global science, full stop. 🧪🔭

I have been doing entirely too much earnest posting about deep things recently, I need to do a proper thread about hippo testicles or something just to keep myself sane. Oh by the way hippos have migratory testicles.

This is the content we need right now

he was afraid of needles! absolute legend www.npr.org/2025/03/03/n...

I feel virology Bluesky should be talking about that www.nytimes.com/2025/02/25/w...

Stand by this: www.politico.com/newsletters/...

I maxed out my credit card, emptied my savings account, and took out a loan to move from Alabama to Bethesda, MD. I don’t even qualify for unemployment since I’ve only worked at NIH for a month. I will be financially and medically devastated. Seeking suggestions for anywhere that’s hiring!!

Powerful, provocative piece from @cbo.bsky.social this morning.

I’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.

I love to see our work pops up in my feed! Glad you liked our paper and thank you for sharing it

New hope for viral coinfection-based therapeutic approach against Herpesviruses! Gene Drive(GD), a self propagating gene-editing technique via Cas9 mediated homologous recombination inserts the GD with red fluorescent (mCherry) into HSV-1 genome. Specific and non-specific (GD-ns) gRNA were tested.

Hello! this is my first post in Bluesky :) Like many of you, I have migrated here to share, connect and stay updated on everything happening in the world of science (although epigenetics and embryology–developmental biology are my absolute favorites!). Let's get started!

Full stream ahead: how one couple is leveraging their love of science to inspire support for research at Fred Hutch www.fredhutch.org/en/news/cent...

Hi to my new followers! I am a virologist at @fredhutch.bsky.social in the team of Keith Jerome. If you are curious about what I do here are 3 options for you: 1. Read our latest paper! We showed that a viral gene drive propagated during HSV-1 infection in mice www.nature.com/articles/s41...

Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇

Giving a first try at Bluesky: We are excited share our latest work! We designed a viral gene against HSV-1 and showed that it spread efficiently during infection in mice www.biorxiv.org/content/10.1...