Conchita
@shoreseashell.bsky.social
π€ 14
π₯ 15
π 1
Postdoc at Sakamoto Lab
@cbmr.science
Science communication enthusiast π§¬π§
reposted by
Conchita
Sakamoto Lab
19 days ago
Latest publication from the lab spearheaded by
@shoreseashell.bsky.social
& in collaboration with
@zeqiraj.bsky.social
is out. Using structural, biochemical & computational tools, this work sheds light on the mechanism of action of BAY-3827 in inhibiting
#AMPK
1/3
www.science.org/doi/full/10....
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Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827
The mechanism and unique molecular/cellular features of the potent and selective AMPK inhibitor BAY-3827 are unraveled.
https://www.science.org/doi/full/10.1126/sciadv.adx2434
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reposted by
Conchita
Sakamoto Lab
4 months ago
Special day for our group
@cbmr.science
as we celebrate the successful defense of our (first) freshly minted PhD, Dr. Conchita Bringas π₯³ Her thesis was based on characterizing novel
#AMPK
inhibitors. Special thanks to the great committee
@rbdamgaard.bsky.social
,Dave Carling & Lykke Sylow.
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Tonightβs moon β¨
#sonyphotography
#moonphotography
#nightphotography
5 months ago
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reposted by
Conchita
Sakamoto Lab
7 months ago
New pre-print from the lab
@cbmr.science
spearheaded by PhD student, Conchita Bringas & in collaboration with
@zeqiraj.bsky.social
@universityofleeds.bsky.social
; providing structure-based molecular insights & cellular actions of the recently identified potent
#AMPK
inhibitor, BAY-3827.
loading . . .
Mechanism and cellular actions of the potent AMPK inhibitor BAY-3827
Inhibition of AMP-activated protein kinase (AMPK) is under increasing investigation for its therapeutic potential in many diseases, including certain cancers. However, existing AMPK-inhibitors availab...
https://www.biorxiv.org/content/10.1101/2025.02.28.640688v1
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