Pat Eyers
@pseudoenzyme.bsky.social
📤 277
📥 57
📝 22
Family, cell signalling, food, chillies, wildlife, dogs and rugby.
reposted by
Pat Eyers
University of Liverpool
3 months ago
One week left! 📣 Apply for our five-year AI Research Fellowships. We’re seeking early career researchers with bold ideas for AI-driven discovery. Fellows receive protected research time, tailored support, and a path to a permanent post. Apply now ▶️
news.liverpool.ac.uk/2025/10/24/u...
0
7
13
That's 3 national championships in a row for
@harvard.edu
women's rugby.
3 months ago
0
1
0
reposted by
Pat Eyers
Simon Cook
3 months ago
I’m really pleased to share the link to a new Cook Lab paper published today in Nature Communications.
www.nature.com/articles/s41...
loading . . .
RAF inhibitors activate the integrated stress response by direct activation of GCN2 - Nature Communications
Three BRAF inhibitors are used to treat melanoma and colorectal cancer. Here, the authors demonstrate that these drugs bind and activate the protein kinase GCN2, a previously unappreciated off-target ...
https://www.nature.com/articles/s41467-025-65376-w
2
29
10
reposted by
Pat Eyers
Pei Yee
3 months ago
Our latest preprint is out! We developed an inducible “RapTag” system that uses ENTAC to chemically recruit USP15 to the unstable protein CTLA4. This induced proximity stabilises and slows down the rapid lysosomal turnover of CTLA4.
@livuni-ismib.bsky.social
www.biorxiv.org/content/10.1...
loading . . .
Targeted recruitment of USP15 enhances CTLA4 surface levels and restricts its degradation.
Induced protein proximity offers powerful new routes to modulate protein fate. While proteolysis-targeting chimeras (PROTACs) promote degradation through E3 ligase recruitment, the converse principle-...
https://www.biorxiv.org/content/10.1101/2025.11.07.687309v1
0
4
5
Very much worth a read. The Lords know what is needed to drive translational research. The Govt?
publications.parliament.uk/pa/ld5901/ld...
loading . . .
House of Lords - Bleeding to death: the science and technology growth emergency - Science and Technology Committee
https://publications.parliament.uk/pa/ld5901/ldselect/ldsctech/192/19203.htm?utm_source=www.synthesisspotlight.com&utm_medium=newsletter&utm_campaign=acids-arynes&_bhlid=fd30bb102635e4950c57c2e941c532c13f7e079b#_idTextAnchor002
3 months ago
0
0
0
reposted by
Pat Eyers
Simon Cook
7 months ago
Together with
@pseudoenzyme.bsky.social
I had a wonderful and very inspiring day at the Dyrk1a Syndrome Community Family Conference on Saturday. Wonderful families and wonderful support from volunteers at the Barnstondale Centre in the Wirral. Thank you for the warm welcome
0
7
2
reposted by
Pat Eyers
University of Liverpool
8 months ago
We’re celebrating a global rise! 🎓 The University of Liverpool is now ranked 147th in the world in the QS World University Rankings 2026 — officially in the Top 150!
#TeamLivUni💙
Read more ⬇️
news.liverpool.ac.uk/2025/06/19/u...
loading . . .
0
22
12
reposted by
Pat Eyers
University of Liverpool
9 months ago
NEWS I We will open a campus in Bengaluru, India, building on our strong existing collaborations in the region. In Delhi today, the Indian Minister of Education formally awarded our VC a Letter of Intent giving official permission for the campus 🇬🇧 🇮🇳 Read more:
news.liverpool.ac.uk/2025/05/26/u...
0
6
4
reposted by
Pat Eyers
Ian Prior
9 months ago
Fantastic to be at the
@royalsociety.org
today celebrating progress and initiatives to support the technician community.
@uk-itss.bsky.social
@livunihls.bsky.social
0
6
2
Naga. That is all.
9 months ago
0
1
0
An atlas of bacterial serine-threonine kinases reveals functional diversity and key distinctions from eukaryotic kinases | Science Signaling
www.science.org/doi/10.1126/...
loading . . .
An atlas of bacterial serine-threonine kinases reveals functional diversity and key distinctions from eukaryotic kinases
The bacterial serine-threonine kinome is a resource for functional studies and drug development.
https://www.science.org/doi/10.1126/scisignal.adt8686
9 months ago
0
7
0
reposted by
Pat Eyers
Babraham Institute
10 months ago
What's the collective noun for
@biochemsoc.bsky.social
Morton Prize winners? We gathered together as many as we could get our hands on, including newest recipient Len. From left to right: Phill Hawkins, Peter Cullen, Robin Irvine, Peter Parker, Roger Williams, Len Stephens and Bob Mitchell.
2
15
7
reposted by
Pat Eyers
Pedro Beltrao
10 months ago
Our work on deriving protein-protein (functional) associations across different human tissues from proteomics data is now published. There is quite a lot in this paper, so I will just touch on a few highlights:
www.nature.com/articles/s41...
loading . . .
A tissue-specific atlas of protein–protein associations enables prioritization of candidate disease genes - Nature Biotechnology
Protein–protein interactions specific to 11 individual tissues are presented in a comprehensive resource.
https://www.nature.com/articles/s41587-025-02659-z
3
135
53
reposted by
Pat Eyers
Simon Cook
10 months ago
I'm am very excited - and little bit emotional - today as we start the two day Symposium to celebrate the achievements and retirement of my colleagues and chief PI3K gurus - Len Stephens and Phill Hawkins
3
26
7
A big day for
@biochemsoc.bsky.social
2026 Morton Lecture awardee Dr Len Stepehns, introduced by
@drsimoncook.bsky.social
@babrahaminst.bsky.social
10 months ago
0
10
3
reposted by
Pat Eyers
Paul Gorst
10 months ago
2
257
43
reposted by
Pat Eyers
Ian Prior
10 months ago
Final week for the early bird deadline for the Small G-protein meeting in Manchester. Talk slots available from submitted abstracts.
#SGP25
@BiochemSoc @SmallGTPases Register here:
bit.ly/SmallG25
loading . . .
Small G proteins in cellular signalling and disease 2025
https://bit.ly/SmallG25
0
5
7
reposted by
Pat Eyers
Biochemical Society
10 months ago
Don't miss out! The earlybird discount and abstract submission deadline for our upcoming small G protein conference is this Thursday 24 April! Submit your abstract for consideration and register now to save £50!
#SGP25
🧪
www.eventsforce.net/biochemsoc/2...
0
3
3
reposted by
Pat Eyers
Simon Cook
10 months ago
Really looking forward to this meeting!
add a skeleton here at some point
0
5
2
A dapper Vinnie Tagliabracci picking up an
@asbmb.bsky.social
Early Career Scolar Award in between social engagements
10 months ago
0
2
1
journals.biologists.com/jcs/article/...
loading . . .
Remembering David Stephens (1971–2024)
In the autumn of 2024, David Stephens, a prominent member of the UK cell biology community and a brilliant scientist, leader and mentor, passed away. With his pragmatism and natural authority, combine...
https://journals.biologists.com/jcs/article/138/7/jcs263972/367609/Remembering-David-Stephens-1971-2024
10 months ago
0
0
0
www.nature.com/articles/s41...
loading . . .
Molecular glues that inhibit deubiquitylase activity and inflammatory signaling - Nature Structural & Molecular Biology
The BRCC36 isopeptidase complex (BRISC) is a deubiquitylase that stabilizes interferon receptors, driving inflammation. We discovered ‘BRISC molecular glue’ inhibitors (BLUEs) that selectively inactiv...
https://www.nature.com/articles/s41594-025-01517-5
10 months ago
0
3
1
reposted by
Pat Eyers
Health and Life Sciences Public Engagement
10 months ago
Science fans of Liverpool - check out
@liverpooluni.bsky.social
Pint of Science nights and grab your tickets here
pintofscience.co.uk/organisation...
🍻
@livunihls.bsky.social
@livuniresearch.bsky.social
@livuninews.bsky.social
add a skeleton here at some point
0
3
7
reposted by
Pat Eyers
Journal of Cell Science
10 months ago
Did you know… It’s free to publish in Journal of Cell Science – there are no submission charges, page charges or colour fees. We also plant a tree for every peer-reviewed article we publish🌳 For details, visit our website:
journals.biologists.com/jcs/pages/re...
1
98
49
Pleased to be in Chicago. Part-science, part to support all our US colleagues
@biochemsoc.bsky.social
@asbmb.bsky.social
10 months ago
0
2
1
Exciting future for Structural RNA
www.science.org/content/blog...
loading . . .
RNA Motifs Coming Into Focus
https://www.science.org/content/blog-post/rna-motifs-coming-focus
10 months ago
0
1
0
reposted by
Pat Eyers
Biochemical Society
10 months ago
We are so proud of all our Biochemical Society 2026 Award winners. Visit our website to find out more about all of the deserving recipients 🧪
#BiochemAwards
ow.ly/bGbY50VwkYF
0
13
8
🥲 Good call.
add a skeleton here at some point
11 months ago
0
0
0
reposted by
Pat Eyers
British Society for Cell Biology
11 months ago
Congratulations to our 2025 Raff PhD medal winner
@impeiyee.bsky.social
from
@liverpooluni.bsky.social
bscb.org/bscb-phd-awa...
2
23
11
reposted by
Pat Eyers
Institute of Systems, Molecular and Integrative Biology
about 1 year ago
We are delighted to announce that we have been awarded a Gold
#AthenaSwan
Award from
@advancehe.bsky.social
! Thank you to the ISMIB Athena Swan Team who made this all possible!
#GenderEquality
|
#TeamLivUni
bit.ly/4jcgcew
0
23
11
reposted by
Pat Eyers
Peter Mace
about 1 year ago
Exciting to open registration for the IUBMB Focussed Meeting on Emerging roles of (pseudo)kinases! Fantastic speakers in an unmatched location, lots of speaking slots available for ECRS. Interested in kinases or pseudokinases? We would love to see you in Queenstown!
www.ivvy.com.au/event/IUBMB2...
2
11
11
MasterChef would be more interesting if everyone started with exactly the same ingredients, plus access to all herbs and spices. Discuss
about 1 year ago
0
1
0
Dogs: Female dominance incoming.
about 1 year ago
0
2
0
Family: pizza without jalapeños is like a broken pencil:pointless
about 1 year ago
0
1
0
Science next with Horace
about 1 year ago
0
0
0
Science, Dog and Curry pictures. Little else.
about 1 year ago
0
3
0
you reached the end!!
feeds!
log in
