Eikan Mishima
@eikan-em.bsky.social
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#Ferroptosis
#HelmholtzMunich
#TohokuUniv
We report a short commentary in
@pnas.org
highlighting that the MALT1 inhibitor MI-2 also inhibits GPX4—an off-target effect to consider in
#ferroptosis
studies.
www.pnas.org/doi/10.1073/...
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MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4 | PNAS
MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4
https://www.pnas.org/doi/10.1073/pnas.2507997122
about 1 year ago
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reposted by
Eikan Mishima
James Olzmann
over 1 year ago
Keystone “Lipids in Cellular Function and Disease” is off to a terrific start with an awesome Keynote lecture from Marcus Conrad on
#Ferroptosis
!
#KSLipids25
👏
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reposted by
Eikan Mishima
ECDO European Cell Death Organisation
over 1 year ago
👇
add a skeleton here at some point
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reposted by
Eikan Mishima
Nature Reviews Molecular Cell Biology
over 1 year ago
ICYMI: New Online! Recommendations for robust and reproducible research on ferroptosis
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Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology, Published online: 09 April 2025; doi:10.1038/s41580-025-00843-2Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in disease. This Expert Recommendation article summarizes ferroptosis regulation and mechanisms and provides recommendations to increase the reproducibility and robustness of ferroptosis research.
https://bit.ly/4jAcwm9
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reposted by
Eikan Mishima
Ferroptosis1
over 1 year ago
Important considerations while studying ferroptosis. A great starting point for anyone entering this field.
add a skeleton here at some point
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reposted by
Eikan Mishima
Nature Reviews Molecular Cell Biology
over 1 year ago
New Online! Recommendations for robust and reproducible research on ferroptosis
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Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology, Published online: 09 April 2025; doi:10.1038/s41580-025-00843-2Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in disease. This Expert Recommendation article summarizes ferroptosis regulation and mechanisms and provides recommendations to increase the reproducibility and robustness of ferroptosis research.
https://bit.ly/4lpBSog
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Happy to share our new review on recommendations for
#ferroptosis
research, now out in NatRevMCB! We cover recommended experimental models, tools, and common pitfalls in the field. Hope this will be a helpful resource for both new and experienced ferroptosis researchers.
rdcu.be/eg58p
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Recommendations for robust and reproducible research on ferroptosis
Nature Reviews Molecular Cell Biology - Ferroptosis is a non-apoptotic type of cell death that is induced by uncontrolled iron-dependent phospholipid peroxidation and has important roles in...
https://rdcu.be/eg58p
over 1 year ago
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Happy to share our design was selected as cover art in MolecularCell🎉 This depicts the moonlighting function of PRDX6 carrying rocks of selenium, named after the goddes of moon Selene.
www.cell.com/molecular-ce...
over 1 year ago
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reposted by
Eikan Mishima
Christian Frezza
over 1 year ago
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization đź§Ş
www.cell.com/molecular-ce...
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PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
Ito et al. highlight peroxiredoxin 6 (PRDX6) as a critical regulator of ferroptosis. As a selenium-acceptor protein, PRDX6 aids in intracellular selenium utilization for efficient selenoprotein biosyn...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00868-2
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🎉Excited to share our new paper – identifying PRDX6 as a key regulator of
#ferroptosis
, acting as a selenium-carrier protein. Now online in Mol Cell.
www.cell.com/molecular-ce...
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PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization
Ito et al. highlight peroxiredoxin 6 (PRDX6) as a critical regulator of ferroptosis. As a selenium-acceptor protein, PRDX6 aids in intracellular selenium utilization for efficient selenoprotein biosyn...
https://www.cell.com/molecular-cell/fulltext/S1097-2765(24)00868-2
over 1 year ago
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