Official release 4.4.0 announced today 😌 Download: www.itksnap.org/download Graphical overview: www.itksnap.org/new440 Happy segmenting!

Hello Bluesky! Welcome to the official Penn ADRD Trajectories, Copathology, and Heterogeneity (PATCH) Lab account for the labs of Drs. Paul Yushkevich, Sandhitsu Das, and David Wolk at the University of Pennsylvania. Stay tuned for updates about our presentations at AAIC25!

youtu.be/gpQ19OPUm34 New integration with nnInteractive (github.com/MIC-DKFZ/nnI...) in ITK-SNAP 4.4.0-alpha2 (itksnap.org) lets you turn scribbles into 3D segmentations in seconds. All thanks to an amazing new model from Fabian Isensee and colleagues at @helmholtzimaging.bsky.social!

Thrilled to see our team's work on the AInSights platform featured! Two years since we went live, and more exciting apps on the way. #AIinHealthcare #ClinicalDecisionSupport #HealthTech #AInSights #AIinHealthcare #ClinicalDecisionSupport #HealthTech www.hcinnovationgroup.com/imaging/arti...

ITK-SNAP (itksnap.org) is now on BlueSky!

🚨Paper alert Very happy to share our last work on #IntrinsicCapacity (IC) in dementia with Lewy bodies #DLB (n=154), compared AD (n=644) 👉DLB patients showed lower IC in all domains (locomotion, vitality, psychology, audition), requiring personalized interventions ! 🔓 shorturl.at/EfrCX

SUPER BOWL CHAMPIONS! THIS ONE’S FOR YOU PHILLY!

The mimicker of Alzheimer’s disease. Progressive amnestic syndrome with: 1) Hippocampal atrophy 2) Older age ~ 80+ 3) Negative AD biomarkers • Caution with amyloid positivity common with aging • Tau PET ideal but not covered • FDG-PET medial > lateral Temporal hypometabolism = supportive

Clinical criteria for limbic-predominant age-related TDP-43 encephalopathy (LATE) alz-journals.onlinelibrary.wiley.com/doi/full/10.... #dementia #neuroscience #NeuroSky #MedSky #neurology

Thank you for the highlight and example case! With #LewyBody disease, posterior hypometabolism is often more prominent than atrophy. This could be related to changes in neuronal integrity of posterior networks by a-synuclein. academic.oup.com/brain/advance-article/doi/10.1093/brain/awae352/7906681