Excited to share our new manuscript in @NatureMicrobiol uncovering a novel mechanism by which viruses orchestrate their survival in the host. We show that #HIV inherently induces the formation of a latent reservoir of viruses, guaranteeing its long-term survival in the host 🧵 #HIVresearch

HIV Reprograms CD4+ T Cells for Latency In a landmark study published in Nature Microbiology, researchers have unveiled a revolutionary insight into the enigmatic interplay between HIV and the immune system's CD4+ T cells. The team led by Plasek Hegde and colleagues has elucidated a novel…

#HIV infection reprogrammes CD4+ T cells for quiescence and entry into proviral latency www.nature.com/articles/s41... (open access) @natmicrobiol.nature.com

Our lncRNA-in-brain review is out in @natrevneuro.nature.com ✨ The emerging roles of long noncoding RNAs in the brain We discuss 🧬 lncRNA roles in brain development, synaptic function, learning, & behavior 💡 Therapeutic potential and future directions. @unswrna.bsky.social @unswbabs.bsky.social

#NewResearch HIV infection triggers transcriptomic remodelling and a quiescence programme via KLF2 and the p53 pathway leading to proviral silencing. #MicroSky 🦠 www.nature.com/articles/s41...

HIV infection of CD4 T cells drives KLF2 and p53 signaling, which downregulate MYC and proliferation pathways, resulting in proviral transcriptional silencing to enhance latent reservoir formation @natmicrobiol.nature.com @saba-valadkhan.bsky.social www.nature.com/articles/s41...