Oscar M Rueda
@ruedalab.bsky.social
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reposted by
Oscar M Rueda
Carlos Caldas 🇵🇹🇮🇱🇪🇺🇬🇧
about 2 months ago
One of the greatest privileges of my career has been to mentor amazing researchers that now run their own labs. Four of them just sent me this picture:
@hrazaalilab.bsky.social
@ruedalab.bsky.social
@stephensammut.bsky.social
and Alex Bruna
@icr.ac.uk
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Fantastic paper by the very talented Kevin Tu! An impressive analysis of the breast cancer TME in a meta cohort of thousands of tumours
add a skeleton here at some point
4 months ago
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reposted by
Oscar M Rueda
MRC Biostatistics Unit
5 months ago
Happy
#WorldStatisticsDay2025
! 🎉 At the BSU, you can find a fantastic group of passionate people driven to improve the way we look at scientific problems and design methods to help us understand the deluge of data we are surrounded by.
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reposted by
Oscar M Rueda
Carlos Caldas 🇵🇹🇮🇱🇪🇺🇬🇧
7 months ago
@ruedalab.bsky.social
and
@caldaslab.bsky.social
with Christina Curtis reported this 6 years ago: genomic subtypes of both ER+ and TNBC determine pattern of late relapse. Theme: some tumors are born to be bad! >300 citations!
www.nature.com/articles/s41...
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Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups - Nature
A statistical framework for breast-cancer recurrence uses long-term follow-up data and a knowledge of molecular subcategories to model distinct disease stages and to predict the risk of relapse.
https://www.nature.com/articles/s41586-019-1007-8
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Are you looking for a statistics/ML postdoc? Come to work with
@antonis02.bsky.social
and me in the NEMO study, an international collaboration aiming to detect ovarian cancer earlier through cutting-edge multi-omics, funded by the Alliance for Cancer Early Detection.
www.cam.ac.uk/jobs/researc...
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Research Associate*/Research Assistant in Multi-omics Early Detection of Ovarian Cancer (Fixed Term)
An exciting opportunity has arisen for a highly motivated Research Associate to join the Centre for Cancer Genetic Epidemiology (CCGE) at the Department of Public Health & Primary Care, University of
https://www.cam.ac.uk/jobs/research-associateresearch-assistant-in-multi-omics-early-detection-of-ovarian-cancer-fixed-term-rs46925
7 months ago
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reposted by
Oscar M Rueda
MRC Biostatistics Unit
9 months ago
We had a fantastic away day yesterday, bringing together our amazing and talented staff and students for a day of sharing, learning and recognising the great people who work at the BSU. Big thanks to the organising team for creating a brilliant day for us all 🤩
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reposted by
Oscar M Rueda
Nature Portfolio
10 months ago
A paper in Nature Communications presents algorithms to estimate the chances of a person having an existing, as yet undiagnosed cancer. These algorithms can be used to triage patients for further assessment to improve chances of an earlier diagnosis.
#medsky
🧪
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Development and external validation of prediction algorithms to improve early diagnosis of cancer - Nature Communications
Diagnosing cancer early and accurately is key to improving patient outcome. Here, the authors have developed algorithms to estimate the chances of having a person having an existing, as yet undiagnosed cancer. These algorithms can be used to triage patients for further assessment to improve chances of an earlier diagnosis.
https://go.nature.com/42Z4DRM
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Very proud of this work led by
@nguyenlab.bsky.social
! Massive effort to characterise clonal diversity in PDTXs from breast cancer
add a skeleton here at some point
10 months ago
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How much data and resolution do we need to estimate homologous recombination deficiency in breast cancer? Rong Zhu answers this question in our latest paper:
febs.onlinelibrary.wiley.com/doi/full/10....
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FEBS Press
This study develops a semi-supervised classifier integrating multi-genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer....
https://febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70041
11 months ago
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Excited to share our latest work on monitoring response to treatment using ctDNA and shallow WGS using a Bayesian Model developed by Solon Karapanagiotis with
@Carloscaldas1960.bsky.social
, Emma Beddowes and
@mortegaduran.bsky.social
febs.onlinelibrary.wiley.com/doi/full/10....
11 months ago
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