"fungi are reliable biomarkers for gut maturation, with the notable emergence of #Saccharomyces and Malassezia as some of the strongest indicators. Fungal composition was strongly associated with infant age and with the later development of both atopic dermatitis and food allergy" #mycobiome

It is always a challenge but also fun to go back to partially completed projects: this manuscript supplementary file happens to be last modified in Nov 2020... Time to wrap things up! #Saccharomyces #lablife

1/2 Happy to share this #Saccharomyces epidemiological study led by @renatokovacs1.bsky.social: retrospective analysis of all patients with S. cerevisiae isolated from sterile body sites between January 2019 and December 2025 in Debrecen. Rare sterile-site infections associated with high mortality!

www.sciencedirect.com/science/arti... Decoding alcoholic beverage and brewing practices of the Qin state during the Warring States period (475-221 BC) based on archaeological evidence. "Qin people mastered brewing and qu production during the Warring States period." #yeast

Prof. Csaba Szabó from University of Fribourg giving an invited talk at our University of Debrecen on the reproducibility crisis in #science!

Most of my at-home fermentation experiments are successful, this one is not :) It took me a looooot of time to get my hands on viable and pure Monascus from red yeast rice products. After inoculating to steamed rice, the Rhizopus-like and Aspergillus-like molds took over the slow-growing Monascus:

Low-level contamination confounds population genomic analysis and also phylogenomics in this example of #yeast #Saccharomyces. Very important: "Contamination rates differed however among sequencing centers: was high for 2 #Saccharomyces studies (2% or 15% of genomes)."

This week we conclude our General and Applied Microbiology Lab class with 1st year BSc students at UDebrecen. We spent the semester with studying sourdough yeasts and bacteria, with spp identification, genetic fingerprinting, and classic microbiological experiments. We also made new sourdoughs...

Exactly 10 yrs ago I had the incredible opportunity to observe horseshoe crabs in their natural habitat, a majestic species I first have seen in David Attenborough's Trials of Life series, back in the 90s, on VHS:) Happy 100th Birthday, Sir! naturephoto-walter.blogspot.com/2016/05/atla...

Real #cask ale or real ale from the UK is a wonderful beverage often described as a "live product", with live yeasts responsible from secondary fermentation and carbonation. I found only one scientific paper on cask ale pubmed.ncbi.nlm.nih.gov/36073539/ so I had to try isolating from it in London:)

Insights from sourdough redefine the domestication landscape of baker's #yeast. #yeastevolution Can't wait to read this @caitismuheil.bsky.social !

We are on a short trip in London, tasting some real #cask ale at The Lucas Arms :)

#Mycosphere This groundbreaking study reveals incredible hidden microbial diversity in tropical ecosystems and expands our understanding of fungal ecology. 🔬 Details: https://www.maxapress.com/article/doi/10.48130/mycosphere-0026-0002#Mycosphere#fungalecology #species #flowerstyle #ecosystems

In #yeast probiotic news: www.fzata.com/post/fzata-i... Fzata's new drug candidate, in fact a probiotic #Saccharomyces, FZ002, is designed to neutralize both of the main C. diff toxins (toxin A and toxin B). Clinical trials, sponsored by NIH, are planned to begin in summer of 2026 upon FDA clearance

Farmhouse #yeast show sexual competence, influencing their evolution trajectory #Farmhouse yeasts show phenotypic diversity but also common domestication traits #yeastevolution www.cell.com/current-biol...

Randy W. Scheckman presenting a special lecture at our University of Debrecen - he won the 2013 Nobel Prize in Physiology or Medicine for using baker’s #yeast to uncover the genetic machinery regulating vesicle transport!

Today we made great progress with a new multi-locus sequence typing approach under development for #Saccharomyces with two BSc students - this is all their work! Looking forward to analyze the sequences :)

Candida Genome Database’s new website is live! #yeast

With my recent trip to Rio de Janeiro, I managed to visit 26 Terrestiral Ecoregions of the 846 existing ones to do at least some nature photography and exploration. Still a lot to go! I also visited 9 Marine Ecoriegions (of 232) and 13 Freshwater Ecoregions (of 426).

www.nature.com/articles/s42... It is so great to see this paper finally out! w/ @alexandraimre.bsky.social we started this project years ago. We checked what phenotypes of the probiotic #yeast are selected for in an experimental 🐭 bloodstream infection in 6 different S. 'boulardii' backgrounds /1

We opened a Brazilian wild #yeast fermented red wine I brought back from Rio. Very nice, strong notes of chocolate and red fruit!

We are deeply saddened to share the news of the passing of David Botstein, a towering figure in modern #genetics and a foundational force behind SGD. www.yeastgenome.org/blog/in-memo... #yeast #modelOrganism

www.biorxiv.org/content/10.6... comparison of commercially available #Saccharomyces #mead yeasts. Our new preprint w/ @balintnemeth.bsky.social and colleagues compares 13 mead #yeast strains for their phenotype, genome, and presents data on metabolites in experimental mead fermentations.

Yesterday at Rio Botanic Garden :)

I arrived to the Federal University of Rio de Janeiro to André dos Santos' lab, meeting with students incl. @raquelvicente.bsky.social who visited us in Debrecen a year ago! Excited to give a course on #yeast genomics :) and present on our results in this enchanting city!

📢 In our new study, we identify the predominant natural route to polyploidy in S. cerevisiae. Stepwise polyploidization operates through iterative cycles of events termed "Sporulate–Endoreplicate–Mate" (SEM). Really excellent work led by @cintiagomez.bsky.social 👏 www.biorxiv.org/content/10.6...

With a 2019 Fuller's vintage ale, celebrating the acceptance of a paper w/ @alexandraimre.bsky.social that we started working on in 2019. So happy to have saved this for all these years! What a long journey! The topic is #yeast probiotics, will be online very soon!

"Ancient co-option of LTR retrotransposons as yeast centromeres" #yeastevolution

With @litinice.bsky.social, we built a haploid resource from 33 wild Taiwanese Saccharomyces cerevisiae strains — including some of the most genetically divergent Asian lineages — to bring natural yeast diversity into a genetically tractable framework. www.biorxiv.org/content/10.6...

Found this almost artistic bottle, probably close to 100 years old, at our Department! Still in great shape and the Congo Red is still vibrant red inside:) this substance is often used in cell will stress experiments with #yeast

We welcome @ola-gorzynska.bsky.social from Wroclaw Medical University in Debrecen! Ola will spend a month in our lab working on clinical #Saccharomyces yeast genomes. 54 Polish isolates' sequences just arrived, so the project starts w/ Andi Harmath and @balintnemeth.bsky.social ! Good luck, Ola!

1/🧵 Major milestone unlocked for mycology! 🍄 We just published a massive genomic resource in 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐃𝐚𝐭𝐚, releasing 2,695 complete circular mitochondrial species assembled from public data This single dataset nearly 𝐓𝐑𝐈𝐏𝐋𝐄𝐒 📈the known mitochondrial diversity of the Kingdom Fungi rdcu.be/eYZ2h

New paper! Here we present the history, geographical distribution, and structure of organizations in #mycology across #Europe, as well as their activities—including journals, magazines, meetings, educational initiatives, and #citizenscience projects. doi.org/10.1007/s105... #FunDive

My first ever hairy tofu, 毛豆腐. Made with a Mucor species starter culture I ordered from Ebay. After 24 hours it was ready and I stir-fried it, the taste was cheese-like and pleasant!

Repeated losses of self-fertility shaped heterozygosity and polyploidy in #yeastevolution

The new year has just started and we are happy to share the news that the new issue of #Yeast (Volume 42, Number 12, December 2025) is finally out!!! 😀😀😀 This issue includes two research articles and two reviews. You can browse it at this link: onlinelibrary.wiley.com/toc/10970061...

Here is our first publication of 2026 which is the first article of a special issue that mark the journal 40 anniversary - happy new year to all the #yeast community

imafungus.pensoft.net/article/1723... Global population genomics redefines domestication and clinical diversity in the Aspergillus flavus–oryzae complex. Our new paper w/ @balintnemeth.bsky.social finally online in IMA Fungus! This has been a long journey, the first idea of this global phylogeny...

"Despite their rarity, yeasts likely play disproportionate roles in nutrient cycling, plant growth, and host interactions". A global synthesis of #yeast in microbiomes

An incredible agART - agar art from PhD students Andrea Harmath and @balintnemeth.bsky.social, depciting our lab's activities in #yeast research from fermentations to bioinformatics :)

As many of us 🎁 things up for the year, make sure all your ℹ️'s are dotted- and all your #yeast emojis are downloaded! If you haven't yet, make sure to add the emojyeast collection to all your 📱💻🖥️⌚️ mayaschuldiner.wixsite.com/schuldinerla... Thanks to the amazing Schuldiner lab for these!

The discovery and patterns of the underlying long-standing mild-effect mutator alleles in S. cerevisiae populations. #Saccharomyces #YeastEvolution

Wow! Population-scale chemical response revealed by a barcoded yeast collection. #Saccharomyces

journals.asm.org/doi/10.1128/... Phylogenomic diversity of clinical #Saccharomyces cerevisiae and the prevalence of probiotic-derived isolates in a tertiary care center - our new paper in collab with @renatokovacs1.bsky.social , with PhD students @balintnemeth.bsky.social and Andrea Harmath! #yeast

I'm honored and excited to participate in the The Human Frontier Science Program's Grant Writing Masterclass in Prague! It is great to be in this beautiful city, with the recent snow the Czech Academy of Sciences' Vila Lanna building looks fantastic!

I first tried U Fleků and both of their house beers after arriving to Prague

The paper Margo Samorokov and I wrote for Brewery History Journal on Estonian farmhouse brewing is now available online, in case anyone is interested. www.breweryhistory.com/journal/arch...

Riding the train from Budapest to Prague for a grant writing masterclass, so far a really good experience! Can't wait to see the city for the first time! #lablife

We are having a great time at NCSU with students @balintnemeth.bsky.social and Andrea Harmath, meeting with the Crook Lab and @alexandraimre.bsky.social over probiotics, with Ignazio Carbone at CIFR over Aspergillus, and soon with the @caitismuheil.bsky.social Heil Lab over yeasts! Wonderful place!