First big piece of research from our SG lab: Fadi's work with Chris Brooke's lab. Flu serially passaged 80X selects a defective genome with improved competition, but is nonviable as a full virus! Notable improvement & safety for DVGs as antiviral RNA therapies! www.biorxiv.org/content/10.1...

@joelrc.bsky.social 's paper on differences between the seasonal H1N1 and H3N2 lineages in their relative capacity to antagonize IFN induction and signaling at the single cell level is out now in PLOS Pathogens: journals.plos.org/plospathogen...

Check out @tonyl1415.bsky.social 's new paper on how the evolutionary potential of the seasonal H1N1 HA gene is influenced by its interactions with neuraminidase! academic.oup.com/ve/article/1...