Joel Rivera-Cardona
@joelrc.bsky.social
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PhD student at UIUC studying the innate immune response to influenza at the single-cell level🇵🇷🏳️🌈
reposted by
Joel Rivera-Cardona
Chris Brooke
7 months ago
Excited to share
@joelrc.bsky.social
's new paper examining the factors underlying cell-to-cell heterogeneity in interferon induction during flu infection:
www.biorxiv.org/content/10.1...
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Intrinsic OASL expression licenses interferon induction during influenza A virus infection
Effective control of viral infection requires rapid induction of the innate immune response, especially the type I and type III interferon (IFN) systems. Despite the critical role of IFN induction in ...
https://www.biorxiv.org/content/10.1101/2025.03.14.643375v1
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reposted by
Joel Rivera-Cardona
Chris Brooke
10 months ago
@joelrc.bsky.social
's paper on differences between the seasonal H1N1 and H3N2 lineages in their relative capacity to antagonize IFN induction and signaling at the single cell level is out now in PLOS Pathogens:
journals.plos.org/plospathogen...
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Seasonal influenza a virus lineages exhibit divergent abilities to antagonize interferon induction and signaling
Author summary Successful replication and transmission of influenza A viruses (IAVs) requires effective subversion of the innate immune response. We developed a new single cell method to examine the i...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012727
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