Martina Delbianco
@delbiancom.bsky.social
📤 429
📥 240
📝 26
Glycan hairpins can now be assembled into materials! Out today in
#JACS
! Big team effort from Nishu, Yadiel, Ana, Dominik, Jesus, Yu!
@mpici.bsky.social
@cicbiogune.bsky.social
,
@cermav.bsky.social
pubs.acs.org/doi/10.1021/...
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Leveraging Glycan–Glycan Interactions to Tune the Conformation of Glycan Hairpins and Build Rigid 3D Architectures
Glycan folding and aggregation remain poorly understood despite their essential roles in structural and biological functions. We present a reductionist approach leveraging a glycan sequence that spont...
https://pubs.acs.org/doi/10.1021/jacs.6c04539
about 1 month ago
0
6
2
Join us at the SMART Symposium: Decoding the Glycome!
#glycotime
about 2 months ago
0
3
0
reposted by
Martina Delbianco
Organic & Biomolecular Chemistry
3 months ago
🔓Don't miss this
#OpenAccess
review from Dominik Weh &
@delbiancom.bsky.social
at
@mpici.bsky.social
in our latest issue looking at how mirror-image glycans can be leveraged to tailor carbohydrate materials Check it out in full on our website🔽
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Leveraging mirror-image glycans in carbohydrate materials
Chirality has become a fundamental design principle to craft peptide materials. In contrast, the systematic exploitation of chirality to build glycan materials remains largely unexplored, despite the…
https://pubs.rsc.org/en/content/articlelanding/2026/ob/d5ob01778e
0
2
2
De novo design of glycan foldamers with programmable tertiary structure out today in
@jacs.acspublications.org
Congrats to Yadiel! With Nishu Yadav, Martin Rosenthal and Yu Ogawa
@mpici.bsky.social
@cermav.bsky.social
pubs.acs.org/doi/10.1021/...
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De Novo Design of Glycan Foldamers with Programmable Tertiary Structure
De novo molecular design has yielded proteins and peptides with structures and functions beyond those found in nature. Despite the potential for glycans to form a broader scope of well-defined tertiary architectures, owing to the numerous conjugation sites and stereocenters, no one has yet built glycans with targeted structures and functions from scratch. Here, we designed glycan sequences that fold into programmable 3D architectures. Starting from first-principles, we create a linear glycan that spontaneously adopts a rigid tertiary structure not reported for natural glycans. Considering stereochemical and spatial orientation, we identify a rigid trisaccharide turn unit that programs backbone directionality, driving folding into antiparallel geometry. The combination of this turn unit with multiple cellulose-like strands completes our design, stabilizing a tertiary sheet-like folding, as confirmed by nuclear magnetic resonance spectroscopy and small-angle X-ray scattering (SAXS). To quantitatively evaluate the conformational landscape of our glycans in aqueous solution, we built a semiautomated protocol that integrates SAXS data with molecular dynamics simulations, demonstrating further the effectiveness of our design principles. This is an important step to design and control conformation populations, not just single structures in the solid state or of unknown prevalence in the solution phase. Together, these results show that glycans can be programmed to adopt rigid tertiary structures on demand, opening new avenues for de novo glycan-based architectures in synthetic glycobiology, catalysis, and materials science.
https://pubs.acs.org/doi/10.1021/jacs.5c20415
4 months ago
0
14
6
Well done Dominik! Leveraging Mirror-Image Glycans in
#CarbohydrateMaterials
out today in
@orgbiomolchem.rsc.org
!
@rsc.org
,
@mpici.bsky.social
pubs.rsc.org/en/content/a...
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Leveraging Mirror-Image Glycans in Carbohydrate Materials
Chirality has become a fundamental design principle to craft peptide materials. In contrast, the systematic exploitation of chirality to build glycan materials remains largely unexplored, despite the ...
https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01778e
4 months ago
0
6
5
reposted by
Martina Delbianco
Max Planck Institute of Colloids & Interfaces (MPICI)
6 months ago
Hats off to our latest
#PhDone
: Nishu Yadav explored how
#carbohydrates
can be engineered to fold into defined, stable structures. Just as in proteins and DNA, in carbohydrates too “form follows function”.
@freieuniversitaet.bsky.social
Supervisor:
@delbiancom.bsky.social
tinyurl.com/5hdm53px
0
11
1
Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces out today in
@angewandtechemie.bsky.social
! Congrats to Nives, Marlene, Junki, Jaap, Kai, Yu, and Katharina!
@mpici.bsky.social
onlinelibrary.wiley.com/doi/10.1002/...
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Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces
Synthetic cellulose-based oligomers assemble into supramolecular nanomaterials with a molecularly controlled, dense presentation of carbohydrates on their surfaces, serving as biological cues.
https://onlinelibrary.wiley.com/doi/10.1002/anie.202515926
6 months ago
0
10
3
reposted by
Martina Delbianco
Max Planck Institute of Colloids & Interfaces (MPICI)
6 months ago
In his
#PhD
, Surusch Djalali examined structure-property correlations in
#oligosaccharides
to create
#carbohydrate
#foldamers
& self-assembling materials. We are late in celebrating his achievement, but his paper on the 1st prototype for de novo
#glycan
design is here to stay!
tinyurl.com/bdfed6vz
0
9
1
🚀 Opportunity for Master’s Students! 🌟 Join us at the
@mpici.bsky.social
to build an innovative application to design carbohydrate structures as part of the
#ERCPoC
GlycoRoads project! Check out our
#glycotime
work:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
7 months ago
1
3
2
Well done Yadiel! Rapid and Reliable Conformational Analysis of Glycans by Small Angle X-Ray Scattering Guided Molecular Dynamics Simulations
@mpici.bsky.social
@cermav.bsky.social
@chemistryeurope.bsky.social
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
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Rapid and Reliable Conformational Analysis of Glycans by Small Angle X‐Ray Scattering Guided Molecular Dynamics Simulations
By explicitly accounting for the conformational dynamics and hydration effects, the molecular dynamics simulations accurately predicted the small-angle X-ray scattering intensities of two glycan hair....
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cphc.202500323
7 months ago
0
9
2
🚀 Exciting Opportunity for Master's Students! 🌟 Join us at
@mpici.bsky.social
to build an innovative application to design carbohydrate structures as part of the ERC-funded GlycoRoads project!
8 months ago
0
4
4
reposted by
Martina Delbianco
FoldNetUK
11 months ago
🧬 Speaking at Foldamers 2025: Dr Martina Del Bianco,
@delbiancom.bsky.social
, Max Plank Institute, Germany Dr Martina Del Bianco will be discussing designing carbohydrate foldamers. 📍 Register now:
foldamers2025.com
0
8
2
reposted by
Martina Delbianco
Max Planck Institute of Colloids & Interfaces (MPICI)
11 months ago
@delbiancom.bsky.social
received the Feltrinelli
#Prize
for her research on carbohydrate-based materials. She synthesizes well-defined
#carbohydrates
using automated methods. With her team, she engineers synthetic sugar chains that adopt shapes from helices to sheets.
#chemsky
tinyurl.com/f7xjj57d
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Martina Delbianco Wins the Prestigious Feltrinelli Prize for Groundbreaking Research on Carbohydrate Materials
https://www.mpikg.mpg.de/6883174/feltrinelli-prize-for-delbianco?c=84258
0
18
5
Join us for a
#PhD
in
#glycotimes
! You'll be part of a collaboration between my group and Yu Ogawa's group at the
@mpici.bsky.social
to design carbohydrates that fold and assemble on demand.
#chemistryjobs
#researchjobs
jobs.mpikg.mpg.de/jobposting/e...
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PhD Position in glycan synthesis and analysis
https://jobs.mpikg.mpg.de/jobposting/e126f30c18c08090b7bdd6d31a6efe519016ee1a0?ref=homepage
12 months ago
0
7
6
From spontaneous to controlled glycan folding! Check out our new chapter in glycan foldamers in
@jacs.acspublications.org
Congrats to Nishu! Great collaboration with Ana, Yadiel, Martin, Yu, Jesus,
@cicbiogune.bsky.social
,
@cermav.bsky.social
,
@mpici.bsky.social
pubs.acs.org/doi/10.1021/...
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Controlling Glycan Folding with Ionic Functional Groups
Glycans are intrinsically flexible molecules that can adopt many conformations. These molecules often carry ionic functional groups that influence glycan’s conformational preferences, dynamics, and ag...
https://pubs.acs.org/doi/10.1021/jacs.4c17992
about 1 year ago
0
5
3
A glycan that performs catalysis Check out this Research Briefing in
@natchem.nature.com
@mpici.bsky.social
www.nature.com/articles/s41...
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A glycan that performs catalysis - Nature Chemistry
In nature, catalytic functions are typically restricted to proteins and ribozymes. Now, a synthetic glycan capable of catalysing a chemical reaction is demonstrated. The folded glycan scaffold positio...
https://www.nature.com/articles/s41557-025-01794-z
about 1 year ago
1
11
2
reposted by
Martina Delbianco
MBP Research & Communication
about 1 year ago
Celebrating International Girls in ICT Day and honoring pioneers like Steve Shirley. Learn more about her story and why Stephanie became Steve:
en.wikipedia.org/wiki/Steve_S...
www.ted.com/talks/dame_s...
www.steveshirley.com/story/
#GirlsInICT
#WomenInTech
#DiversityInTech
#Leadership
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Steve Shirley - Wikipedia
https://en.wikipedia.org/wiki/Steve_Shirley
0
1
2
reposted by
Martina Delbianco
Jennifer Kohler
about 1 year ago
Registration is open for the 2025 Gordon Research Conference on Carbohydrates and the associated Gordon Research Seminar! 🧪 We have a exciting line-up of confirmed speakers and more to be added!
www.grc.org/carbohydrate..
. The conference will be held June 15 - 20 in Holderness, NH.
0
7
6
reposted by
Martina Delbianco
Oliver Maguire
about 1 year ago
🚨
#Postdoc
opportunity in Systems Chemistry!🚨 Please Share! Interested in creating new decision-making materials based on electrochemically programmable protein networks? Then join my group! 2-year Postdoc supported by
#ERC
@erc.europa.eu
at
@uobchemistry.bsky.social
#chemsky
See link for more:
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Research Fellow in Systems Chemistry at University of Birmingham
Discover an exciting academic career path as a Research Fellow in Systems Chemistry at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
https://www.jobs.ac.uk/job/DMD121/research-fellow-in-systems-chemistry
1
6
6
One week left to apply! Join our group at
@mpici.bsky.social
to build a software for
#glycan
design!
#glycotime
#ERCPoC
@erc.europa.eu
add a skeleton here at some point
about 1 year ago
0
2
4
reposted by
Martina Delbianco
Nature
about 1 year ago
Book review 📚 Against the odds: 12 women who beat bias to succeed in science
https://go.nature.com/4brxuAw
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Against the odds: 12 women who beat bias to succeed in science
A book deftly highlights how women have been considered unsuitable as researchers for reasons other than their ability and commitment.
https://go.nature.com/4brxuAw
1
83
24
reposted by
Martina Delbianco
Nature Chemistry
about 1 year ago
A glycan foldamer that uses carbohydrate–aromatic interactions to perform catalysis, from Martina Delbianco
@delbiancom.bsky.social
and Kaimeng Liu.
www.nature.com/articles/s41...
#chemsky
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A glycan foldamer that uses carbohydrate–aromatic interactions to perform catalysis - Nature Chemistry
In nature, catalysis is generally performed by proteins and ribozymes. Now it has been shown that glycans can be designed to perform catalysis. Exploiting carbohydrate–aromatic interactions, a glycan ...
https://www.nature.com/articles/s41557-025-01763-6?utm_source=bluesky&utm_medium=social&utm_campaign=nchem
0
13
2
Thank you very much for this highlight of our paper!
www.thieme-connect.com/products/ejo...
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Automated On-Resin Synthesis of Oligosaccharides Bearing a Phosphoethnolamine Unit
Thieme E-Books & E-Journals
https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-2518-3079
about 1 year ago
1
2
0
Can glycans catalyze chemical reactions? Check out our glycan foldamer that uses carbohydrate–aromatic interactions to perform catalysis, today out in
@naturechemistry.bsky.social
Big congrats to Kaimeng!
@mpici.bsky.social
www.nature.com/articles/s41...
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A glycan foldamer that uses carbohydrate–aromatic interactions to perform catalysis - Nature Chemistry
In nature, catalysis is generally performed by proteins and ribozymes. Now it has been shown that glycans can be designed to perform catalysis. Exploiting carbohydrate–aromatic interactions, a glycan ...
https://www.nature.com/articles/s41557-025-01763-6
about 1 year ago
0
21
10
reposted by
Martina Delbianco
MBP Research & Communication
about 1 year ago
📢 ERC Info Sessions: Widening European Participation 🗓️ 6 & 12 March 2025 | ⏰ 9:30-12:00 CET | 🌐 Online 💡 Tips on ERC StG, CoG, AdG proposals, budgets & ethics. ✅ Learn from ERC experts & grantees. 🔗 Register 👉🏽
erc.europa.eu/news-events/...
#ERC2025
#ResearchFunding
#HorizonEurope
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ERC info sessions for Widening European Participation
How to apply for an ERC grant? How to write a successful proposal? How to find support?
https://erc.europa.eu/news-events/events/erc-info-sessions-widening-european-participation
0
4
3
Postdoctoral Position in Data Science for Glycan Design available in my group at
@mpici.bsky.social
! Join us to develop a platform that integrates
#moleculardynamics
simulations and
#dataanalytics
to facilitate the design of
#glycans
#glycotimes
#ERCPoC
jobs.mpikg.mpg.de/jobposting/c...
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Postdoctoral Position in Data Science for Glycan Design
https://jobs.mpikg.mpg.de/jobposting/c0d6de658ccec1088ff1e62fa5c50d66c1eac1200?ref=homepage
over 1 year ago
0
8
13
reposted by
Martina Delbianco
MBP Research & Communication
over 1 year ago
Exploring LLMs in Scientific Writing Shared my thoughts on the challenges & opportunities LLMs bring to research writing. 📖 Read here:https://www.mbp-rnc.com/news/archive 📅 Attending the "LLMs & Scientific Publishing" workshop on 11.02.2025 in Frankfurt!
#LLM
#ScientificWriting
0
2
2
reposted by
Martina Delbianco
MBP Research & Communication
over 1 year ago
Missed the ERC PoC 2025 webinar? No worries—I’ve summarized the key takeaways! 📌 Eligibility, proposal strategy & expert insights—everything you need to strengthen your application. 📙 Read the full breakdown here:
www.mbp-rnc.com
#ERCPoC
#ResearchFunding
#GrantWriting
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MBP-R&C: Strategic Research Consulting Services
Key takeaways from the ERC PoC webinar: Eligibility, proposal strategy, and expert insights.
https://www.mbp-rnc.com
0
2
2
reposted by
Martina Delbianco
MBP Research & Communication
over 1 year ago
Our First Newsletter is Live! Stay ahead with funding updates, collaboration opportunities & insights on research funding. ✅ New consultancy launch ✅ Online booking ✅ Must-see funding calls 💡Read:
www.mbp-rnc.com/news/archive...
📩Subscribe:
www.mbp-rnc.com/news/subscribe
#ResearchFunding
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MBP-R&C: Strategic Research Consulting Services - 01-2025-01
https://www.mbp-rnc.com/news/archive/01_2025-01
0
2
2
reposted by
Martina Delbianco
MBP Research & Communication
over 1 year ago
I’ve put together a Starter Pack of funding agencies & programs to help
#researchers
,
#startups
, and
#innovators
navigate their options. This list should help you keep up to date on your options.
#FundingOpportunities
#Innovation
#ResearchFunding
go.bsky.app/F9Vvvdm
add a skeleton here at some point
0
6
4
reposted by
Martina Delbianco
Matthew B. Plutschack
over 1 year ago
Another congrats to all
#ERCPoC
winners. For those of you unfamiliar with the program, the next round of applications is just around the corner The ERC Proof of Concept 2025 webinar is tomorrow (Jan 29, 10:00–12:00 CET) Register now so you don't miss expert tips and live Q&A
#ERC
#ResearchInnovation
add a skeleton here at some point
0
2
1
reposted by
Martina Delbianco
European Commission
over 1 year ago
Europe 💙 scientific excellence. Today, the European Research Council announced 134 winners of the 2024 Proof of Concept Grant competition. Each project received €150,000 to help them turn their research, from saving lives to fighting food fraud, into tangible solutions ↓
europa.eu/!cGG9jc
2
185
22
reposted by
Martina Delbianco
Matthew B. Plutschack
over 1 year ago
Do any of these resonate with you? Are there any key ones we missed? Would be happy to discuss! 👉
www.mbp-rnc.com/contact-mbp/...
add a skeleton here at some point
0
2
1
reposted by
Martina Delbianco
Max Planck Institute of Colloids & Interfaces (MPICI)
over 1 year ago
@delbiancom.bsky.social
will develop tools to design
#glycans
(the most abundant organic molecules) w. ad hoc shapes that can then be used in
#therapeutics
&
#materials
"GlycoRoads: A platform for the de novo design of glycans" Stay tuned for an upcoming call to join the
#ERC
project
#ChemSky
add a skeleton here at some point
0
7
2
Super excited to be selected for the
#ERCPoC
! Within
#GlycoRaods
we will develop tools to design
#glycans
with ad hoc shapes!
@mpici.bsky.social
erc.europa.eu/news-events/...
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134 researchers supported to turn their science into practice
In the final round of the 2024 European Research Council (ERC) Proof of Concept grant competition, 134 projects will receive support, bringing the total number of grants awarded under the 2024 work pr...
https://erc.europa.eu/news-events/news/Proof-of-Concept-Grants-2024
over 1 year ago
2
3
1
Highly recommended!
add a skeleton here at some point
over 1 year ago
0
3
1
reposted by
Martina Delbianco
Matthew B. Plutschack
over 1 year ago
Book a meeting now 👇
add a skeleton here at some point
0
3
1
Check it out!
add a skeleton here at some point
over 1 year ago
0
3
0
reposted by
Martina Delbianco
Matthew B. Plutschack
over 1 year ago
Curious about how I can help lighten your work load. Book a free meeting here 👇
add a skeleton here at some point
0
4
1
reposted by
Martina Delbianco
MBP Research & Communication
over 1 year ago
Thrilled to announce that MBP Research & Communication officially launches 1.1.2025 Huge thanks to all who reached out after my departure from CTC. At MBP-RNC, we’re helping researchers write winning research proposals, and communicate effectively https://www.mbp-rnc.com #ResearchFunding #Chemistry
0
5
1
reposted by
Martina Delbianco
Matthew B. Plutschack
over 1 year ago
Thrilled to announce the launch of MBP Research & Communication! 🎉 We empower researchers with: ✔️ Strategic R&D Consultation ✔️ Proposal Writing & Funding Acquisition ✔️ Scientific Communication ✔️ Digital Tool Co-Creation Let’s collaborate! 👉
www.mbp-rnc.com
#ResearchProposalWritingServices
0
6
2
Thoughts for the future of
#carbohydratematerials
in
@nchembio.bsky.social
@mpici.bsky.social
www.nature.com/articles/s41...
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Thoughts for the future - Nature Chemical Biology
As Nature Chemical Biology approaches its third decade we asked a collection of chemical biologists, “What do you think are the most exciting frontiers or the most needed developments in your main fie...
https://www.nature.com/articles/s41589-024-01802-2
over 1 year ago
1
7
2
Synthetic chitin oligosaccharide nanocrystals and their higher-order assemblies out today in Chem Sci! Congrats to Surusch!
@roysocchem.bsky.social
,
@mpici.bsky.social
,
@cermav.bsky.social
pubs.rsc.org/en/content/a...
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Synthetic chitin oligosaccharide nanocrystals and their higher-order assemblies
Self-assembly is a powerful strategy for creating complex architectures and elucidating the aggregation behaviors of biopolymers. Herein, we investigate the hierarchical assembly of chitin using a bot...
https://pubs.rsc.org/en/content/articlelanding/2025/sc/d4sc07549h
over 1 year ago
0
10
4
reposted by
Martina Delbianco
Max Planck Institute of Colloids & Interfaces (MPICI)
over 1 year ago
#PhD
to develop synthetic
#carbohydrate
materials within the project "Dynamic
#Hydrogels
at
#Biointerfaces
". 1) prepare oligo- &polysaccharides resembling natural & unnatural structures 2) study their aggregation 3) generate tunable
#biomaterials
#ChemSky
#Job
tinyurl.com/3j7wbpj7
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PhD position to develop synthetic carbohydrate materials
https://tinyurl.com/3j7wbpj7
0
10
3
#PhDposition
available in my group at the
@mpici.bsky.social
! Join us to develop new
#carbohydratematerials
#chemistryjobs
#researchjobs
#glycotime
jobs.mpikg.mpg.de/jobposting/a...
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PhD position to develop synthetic carbohydrate materials
https://jobs.mpikg.mpg.de/jobposting/a34ba3e3966516e7b6dbb85db30c632b3ebf2d430?ref=homepage
over 1 year ago
0
5
9
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