Take a look at this paper from Qi Sun, Zhiyong Wang et al. in our latest issue using electrochemical generation of ketyl radicals for the synthesis of α-alkenylated nitriles #orgchem 📍University of Science and Technology of China

Be sure to read a paper in our latest issue by Josiah K. Nisly & Steven R. Kass from the University of Minnesota reporting an electrostatically enhanced bifunctional enantioselective thiourea catalyst #orgchem Find it in full below👇

🔓Don't miss this #OpenAccess review from Dominik Weh & @delbiancom.bsky.social at @mpici.bsky.social in our latest issue looking at how mirror-image glycans can be leveraged to tailor carbohydrate materials Check it out in full on our website🔽

📢Our latest issue is now online! Check out the research behind the cover by Yimin Hu & co. from Anhui Normal University on a three-component tandem benzyl-C(sp3)–H functionalization via thermally generated arynes with phenazine #orgchem pubs.rsc.org/en/content/a...

Read this paper by Reuben Peters, Justin Siegel, Dean Tantillo & co. @iastateresearch.bsky.social & @ucdavis.bsky.social on mechanistic molecular modeling of the ent-copalyl diphosphate synthase from Arabidopsis thaliana #orgchem #compchem Find in full here🔽

🔓Don't miss this #OpenAccess research in our latest issue from Olga García Mancheño, Monika Schönhoff & co. @uni-muenster.de describing new supramolecular light-switchable triazole-hosts for photoresponsive anion binding #orgchem #supramolecular Check it out in full👇

Check out this paper by Wei-Cheng Yuan, Yong You et al. from Chengdu University in our latest issue reporting a photoredox-catalyzed Giese reaction for the synthesis of γ-nitro alcohols #orgchem Read their full report on our website🔽

🔓Take a look at #OpenAccess research by Atsushi Yoshimori, Kazuhiro Abe, Satoshi Yokoshima et al. on the design, synthesis & structural analysis of a gastric proton pump inhibitor with a diaza-tricyclic skeleton #orgchem 📍Hokkaido University, @en.nagoya-u.ac.jp

🔓Don't miss this #OpenAccess paper in our latest issue from Shiqing Xu & co. @tamu.bsky.social reporting the discovery of a potent main protease inhibitor by regioselective multicomponent synthesis of α-boryl ureas #orgchem Check it out in full on our website🔽 pubs.rsc.org/en/content/a...

📢Our latest issue is now online! 🔓Check out the #OpenAccess review behind the cover by Basab Bijayi Dhar & co. from Shiv Nadar University looking at C(sp3)–H halogenation using first-row transition metal catalysts under homogeneous conditions #orgchem pubs.rsc.org/en/content/a...

🔓Be sure to read in our latest issue research by Alexander Ciupa @liverpooluni.bsky.social discovering novel fluorescent sensors using high-throughput DoE synthesis of chalcones and pyrazolines #orgchem #sensors Find the full report here🔽

📢We are delighted to announce our #OpenCall for papers to our Electrosynthesis themed collection #chemsky #electrochem Guest Editors: Alastair Lennox, @lundbergchemlab.bsky.social, Lei Wang & Zhong-Wei Hou Deadline: 30th June 2026 Find more about the collection🔽 www.rsc.org/publishing/j...

🔓Don't miss this #OpenAccess paper by Spyridon Mourtas & co. at the University of Patras reporting the use of homoserinyl γ-aldehyde–containing peptides in solid-phase reductive amination #orgchem #peptides Check it out on our website👇

Check out research in our latest issue by Weichao Xue, Xueli Zheng & co. from Sichuan University using electrochemical cross-electrophile coupling of unactivated tertiary alkyl bromides with benzyl chloride to access quaternary stereocenters #orgchem Read in full here🔽

Take a look at this review by Mrittika Mohar, Tanmay Das & Alakananda Hajra covering the recent advances in the synthesis and applications of oxaborole derivatives in our latest issue #orgchem 📍Visva-Bharati University

🔓Read this #OpenAccess paper in our latest issue by Eric A. Nicol & Adrian L. Schwan @uofguelph.bsky.social describing a computational investigation of the thermal elimination chemistry of β-borylated sulfoxides #orgchem #compchem Find their full report below👇

🔓Don't miss this #OpenAccess paper by Camilla Loro, Raffaella Bucci from the University of Milan in our latest issue building parallel β-hairpins using electrochemical synthesis of a new isoxazoline scaffold #orgchem Check it out in full on our website🔽

📢Our latest issue is now online! 🔓Check out the #OpenAccess review behind the cover by Michal Szostak, Chinnappan Sivasankar & co. at Rutgers University & Pondicherry University covering the synthesis, carbene generation and reactivity of diazo compounds #orgchem pubs.rsc.org/en/content/a...

🔓Read a #OpenAccess paper in our latest issue by @prof-ian-fairlamb.bsky.social, @unsworthchem.bsky.social & co. @york.ac.uk reporting innovations to the ‘Clip-Cycle’ approach for functionalised pyrrolidines, pyrrolizidines and indolizidines #orgchem Find it in full🔽

🔓Don't miss this #OpenAccess paper in our latest issue by Stephen G. Withers & co. from @science.ubc.ca synthesising carbagalactosyl 1,2-aziridines and -epoxides as glycosidase inhibitors #orgchem Check it out in full here👇

Check out this paper from Junhong Li, Xuanxuan Chen, Xin Wu & co. at Xiamen University in our latest issue using a simple bis-squaramide with charge-enhanced acidity for anion recognition in water #orgchem #supramolecular Read their full report below🔽

Take a look in our latest issue at research from Ja Young Cho, Taejung Kim & co. reporting the synthesis-enabled conformational assignment of natural N-acyl l-phenylalanine derivatives from freshwater sponge–associated Micromonospora sp. MS-62 #natprod #orgchem 📍KIST

🔓Be sure to read this #OpenAccess paper by Keisuke Tomohara, Hisanori Nambu, Takeru Nose et al. at Kyoto Pharmaceutical University describing N-to-C peptide elongation by ammonia-Ugi reaction for self-assembling elastin-like short peptides #orgchem Find it in full here👇

🔓Don't miss this #OpenAccess review in our latest issue by Niamh Lehane & Patrick J. Guiry from @ucddublin.bsky.social looking at the recent advances in Pd-catalysed decarboxylative asymmetric allylic alkylation #orgchem Check it out in full on our website🔽

📢Our latest issue is now online! 🔓Check out the #OpenAccess paper behind the cover by Hari Prasad Kokatla & co. from NIT Warangal using a metal- and hydride-free approach for the chemoselective reduction of α-keto aldehydes by rongalite in water #orgchem pubs.rsc.org/en/content/a...

Be sure to read in our latest issue this paper by Charles H. Chen & co. at @astra-zeneca.bsky.social enabling effective mRNA delivery to the lungs via new oxabispidine-derived ionizable lipid nanoparticles #medchem #orgchem Find it in full on our website🔽

🔓Don't miss this #OpenAccess paper by Bidraha Bagh et al. from NISER Bhubaneswar using a cobalt-catalyzed hydrosilylation approach for the reductive deoxygenation of tertiary alcohols #orgchem Check it out below👇

Check out research from Ryohei Yamakado & co. at Yamagata University in our latest issue showing how X-shaped π-conjugated fluorophores enable cooperative ion-pair recognition with multicolour emission #orgchem Read their full report here🔽

🔓Take a look in our latest issue at this #OpenAccess paper by Anna Mkrtchyan, Andrei Malkov, Ashot Saghyan et al. reporting the synthesis of enantiomerically enriched β-N-amino (S)-α-alanine analogs #orgchem 📍Yerevan State University, @lborouniversity.bsky.social

Don't miss your chance to present your research at Directing Biosynthesis VIII! ⏳Time is running out until the oral abstract deadline on the 2nd of February▶️ rsc.li/dbviii Be sure to join us and the rest of the #Biosynthesis community in Manchester this summer #natprod #secmet #DBVIII

Be sure to read this review looking at the recent advances in the photocatalytic synthesis of isoquinoline-1,3-dione derivatives by Jin-Wei Yuan & co. from Henan University of Technology in our latest issue #orgchem #photochem Find it on our website👇

Don't miss this paper in our latest issue from José Kovensky, Vincent Chagnault et al. at @upjv-univ.bsky.social looking at sulfonated, sulfated thioglycosides and multivalence in heparanase inhibition #orgchem Check it out in full here🔽

📢Our latest issue is now online! 🔓Check out the #OpenAccess research behind the cover by @michaelaeverly.bsky.social & Patrick J. Hrdlicka from @uidaho.bsky.social using single-stranded LNA/MOE mixmers and chimeric Invader:XenoRNA probes for DNA targeting #orgchem pubs.rsc.org/en/content/a...

Don't miss this review in our latest issue by Rafał Loska et al. from the Institute of Organic Chemistry, PAS looking at how nitrones can be used as directing groups in transition metal-catalysed C–H activation #orgchem Check it out in full on our website🔽

Check out #OpenAccess research from Christopher Batchelor-McAuley, @joannamcgouran.bsky.social & co. @tcddublin.bsky.social showing how electrochemically-generated ferricyanide enables thiol–ene capture of protein–protein binding #orgchem Read in full below👇

Well done Dominik! Leveraging Mirror-Image Glycans in #CarbohydrateMaterials out today in @orgbiomolchem.rsc.org ! @rsc.org, @mpici.bsky.social pubs.rsc.org/en/content/a...

Take a look at a #OpenAccess paper in our latest issue from Ashwani Sharma & co. reporting a label-free fluorescence-assisted method for RNA engineering of three-way junctions #orgchem 📍IISER Tirupati

Read this review focused on the recent advances in coupling reactions on heteroaromatic rings via C–H bond functionalization by Nai-Xing Wang, Dumitra Lucan, Yalan Xing et al. at the Chinese Academy of Sciences & @hofstrau.bsky.social #orgchem Find it on our website👇

Don't miss this paper by Junichiro Yamaguchi & co. from Waseda University describing a transition-metal-free deoxygenative functionalization of trifluoromethyl ketones offering a concise and efficient route to benzylic CF3 scaffolds #orgchem Check it out in full here🔽

📢Our first issue of 2026 is now online! 🔓Check out the #OpenAccess paper behind the cover from @furthlab.bsky.social & co. at @uu.se using heterocyclic scaffold-fused dimethoxy-dibenzocyclooctynes for photoactivatable click chemistry to create this great image #orgchem pubs.rsc.org/en/content/a...

Take a look in our latest issue at this paper from Wei-Min Liu & co. demonstrating an unconventional synthetic pathway for the reaction of alkynyl sulfonium ylides with aromatic acid anhydrides #orgchem 📍Fu Jen Catholic University

Be sure to read research from Chada Raji Reddy et al. at CSIR-IICT in our latest issue presenting the hydrogen atom transfer-assisted dearomative ipso-annulation of N-benzylacrylamides to azaspirocycles #orgchem Find it in full below👇

Don't miss in our latest issue this paper from Yangen Huang & co. at Donghua University on the photoredox catalyzed synthesis of β-trifluoromethyl β-aminoketones #orgchem Check it out in full on our website🔽

Check out research exploring DMSO as a versatile radical reagent for organic transformations by Saravanan Preethika & Rajagopal Nagarajan at the University of Hyderabad in our latest issue #orgchem Read their full report here👇

Take a look in our latest issue at a paper by Salvador Blasco, M. Teresa Albelda, Enrique García-España et al. reporting the self-assembly of azamacrocyclic ligands into vesicular structures #orgchem #supramolecular 📍 @uv.es

Read research by Bor-Cherng Hong et al. from the National Chung Cheng University in our latest issue describing one-pot cyclobutane synthesis via sequential [2+2] photocycloaddition and photo-Nef reaction of nitroalkenes and 2-vinylpyridines #orgchem Find in full below🔽

🔓Don't miss this #OpenAccess paper from Charlotte Hind, @jennifer-hiscock.bsky.social & co. @kent.ac.uk, @ukhsa.bsky.social & @crhorizons.bsky.social investigating supramolecular self-associating amphiphiles as antimicrobials against ESKAPE pathogens Check it out below👇

Check out this review in our latest issue by Rambabu Dandela et al. from ICT Bhubaneswar examining the recent advances in the catalytic chemoselective C–N and C–O cross-coupling of amino alcohols #orgchem Read the full article here🔽

Take a look at a paper by Xiaoyu Liu, Xiaozhen Jiao, Ping Xie & co. in our latest issue describing the synthesis of isoxazoline analogs of stellettins #orgchem #naturalproducts 📍Peking Union Medical College

Be sure to read research from Sungduk Gwak, Hyeok-Jun Kwon, Hogyu Han et al. at Korea University reporting a new diazo-transfer reagent for the metal-free conversion of amines to azides in our latest issue #orgchem Find their full report on our website👇