Our ambition to combine artificial intelligence with fundamental biology and medicine continues to evolve as we welcome Mihaela van der Schaar as our Chief AI Scientist. Read more: www.crick.ac.uk/news/2026-06...

An international team of scientists, led by @charlesswanton.bsky.social lab at the Crick and @ucl.ac.uk and funded by @cancerresearchuk.org, have identified a signature of 14 proteins in the blood that can predict lung cancer risk over five years before diagnosis. www.crick.ac.uk/news/2026-06...

Maybe I’m biased, but I’m starting to think R is the best language for agentic engineering. #rstats cornball.ai/posts/cortez...

Middlemarch rightly in first place for “written in English”, but given this is for novels available in English, maybe it should come second to In Search of Lost Time. www.theguardian.com/books/ng-int...

The people who think they are good at everything because they are good at coding are also bad at coding.

Don't you f**king dare.

“Learning without thought is labor lost; thought without learning is perilous.” — Confucius, Analects

🥁🎉The Psychosis Collective proudly presents our first preprint 𝐂𝐥𝐨𝐳𝐚𝐩𝐢𝐧𝐞 𝐬𝐮𝐩𝐩𝐫𝐞𝐬𝐬𝐞𝐬 𝐚𝐮𝐭𝐨𝐢𝐦𝐦𝐮𝐧𝐢𝐭𝐲 𝐝𝐫𝐢𝐯𝐢𝐧𝐠 𝐩𝐬𝐲𝐜𝐡𝐨𝐬𝐢𝐬-𝐥𝐢𝐤𝐞 𝐛𝐞𝐡𝐚𝐯𝐢𝐨𝐮𝐫 𝐢𝐧 𝐦𝐢𝐜𝐞 𝘈 𝘥𝘪𝘴𝘤𝘰𝘷𝘦𝘳𝘺 𝘫𝘰𝘶𝘳𝘯𝘦𝘺 𝘪𝘯 𝘵𝘩𝘳𝘦𝘦 𝘢𝘤𝘵𝘴 starring Le He & Harriet Feldman www.biorxiv.org/content/10.6... We wanted to understand how antipsychotics work. Thread🧵

Fascinating that Galileo's reputation as a "big ideas" scientist (and they don't get much bigger than Galilean relativity, principle of equivalence, and light having a speed) can be broadened by the finding he was also on top of the details/maths. www.science.org/content/arti...

Except literally every data analysis or model I've ever asked AI to build has contained at least one error: www.nature.com/articles/d41... Common response: "But someone just needs to give AI detailed instructions..." But who is the "someone" in that sentence? And how did they get their expertise?

I'm so excited to announce the first release of my newest #Rstats package, {adrftools}! This package facilitates estimation, visualization, and testing for the causal effect of a continuous (i.e., non-discrete) treatment. 🧵 1/10 #statssky #episky #causalinference

Job offer: PhD-level biostatistician with ML&omics experience to work on prediction models for CAR T cell therapy, in an exciting clinical trial - spatial omics - data science consortium (LOOP/INTeRCePT3.0 centered in Zurich; this position in Heidelberg) embl.wd103.myworkdayjobs.com/en-GB/EMBL/j...

“It is a fault to wish to be understood before we have made ourselves clear to ourselves.” — Simone Weil, Gravity and Grace

Hannah Arendt did not mince words, did she? 'Totalitarianism replaces all first-rate talents with crackpots and fools whose lack of intelligence and creativity is still the best guarantee of their loyalty.' From "The Origins of Totalitarianism" (1951)

“Selfish — a judgment readily passed by those who have never tested their own power of sacrifice.” — George Eliot, Silas Marner

Would love to see more people on LinkedIn with 'non-strategic leader and non-systems thinker' in their bio. Like, just really focused on tactical execution and solving specific things reliably.

Last Christmas I gave you my heart. The very next day You gave it a weigh.

Cool. Classical billiards can compute - but only "for some value of billiard table" I think. arxiv.org/abs/2512.19156

I cannot be trusted to attend a meeting without a calendar invite

MIT's famous 'Missing Semester' course (for the Independent Activities Period in January is back. missing.csail.mit.edu/2026/

Why does anyone use the Wilcoxon test for anything? It's not even transitive. It's sensitive to things one most likely is not looking for (changes in distribution shape) and relatively insensitive to what one usually is looking for (change in location). www.sciencedirect.com/science/arti...

How popular AI apps produce a non-scientist’s idea of quality science kucharski.substack.com/p/the-shallo...

How does immunotherapy work, and why do some patients respond while others don’t? Book our free talk by Samra Turajlic, head of the Cancer Dynamics Lab here at the Crick, Director of @cruk-mi.bsky.social and head of the UK-wide MANIFEST programme. www.eventbrite.co.uk/e/crick-cras...

In honor of National Poetry Day, the greatest parody rewrite of all time:

Am contributing to a collaborative dry-wet project proposal and everyone incl. myself thinks I should be writing about fancy algorithms. Instead, I spend all time on experimental design,power, what do we know or not, what do we aim to show? And on 2nd thought, that's probably OK for a statistician.

Listen to our director Edith Heard on BBC Radio 4 Woman’s Hour - discussing her career, working with AI and the importance of attracting the best global scientific talent to the UK. www.bbc.co.uk/sounds/play/...

Listen to Sonia Gandhi, Assistant Research Director at the Crick, on the latest episode of BBC 4’s The Life Scientific. Sonia discusses her lab’s use of stem cells to drive the development of drugs and other therapies for Parkinson’s patients. www.bbc.co.uk/programmes/m...

So often there’s a gulf between knowing (a particular aspect of) a topic and understanding it from multiple perspectives. Like the analogy here to matrices vs linear algebra.

Exciting day for @crick.ac.uk today: Edith Heard takes over as Director We're looking forward to this new chapter in the story www.crick.ac.uk/about-us/lea...

We didn't randomize, and there was no allocation concealment or blinding, and we can't really be sure what intervention they got or how the outcomes were measured, but we emulated a trial by drawing a DAG.

Just finished The Names by @florenceknapp.bsky.social What a heart-wrenching story, beautifully structured and shining with empathy. One to ‘cherish’

For the math folks on here: NSF has suspended Terry Tao's grant. www.nsf.gov/awardsearch/...

Time for your yearly reminder that “We need less research, better research, and research done for the right reasons”. #OTD 1948 Douglas Altman b (d 3 June 2018) “One of the most influential medical statisticians of the past 50 years” he led reforms in medical research reliability & reporting. 1/3

AI slows down experienced developers (against their expectations) in a randomized controlled trial of AI coding effectiveness. metr.org/Early_2025_A...

Join @dremmacbw.bsky.social, a Senior Clinical Research Fellow at the Crick as she explains how her team are working to improve understanding of the biology of long COVID and discovering new ways to both prevent and treat this complex disease. www.youtube.com/watch?v=JMNe...

Congratulations to the Crick’s Samra Turajlić on her new appointment as Director of the @cruk-mi.bsky.social 🥂

"Why worry about your privacy If you aren't doing anything wrong?"

Good Science xkcd.com/3101/

"Since her death in 1979, the woman who discovered what the universe is made of has not so much as received a memorial plaque. Her newspaper obituaries do not mention her greatest discovery. LET ME TELL YOU ABOUT CECILIA PAYNE:" #WomenInScience #WomenInSTEM #History 1/8

Starting to look like I might not be able to work at Harvard anymore due to recent funding cuts. If you know of any open statistical consulting positions that support remote work or are NYC-based, please reach out! 😅

Every week I'm reminded of how measurement, statistics, design, bias and error are so often treated as sidecars to "the science" in clinical research. It seems like the funders are coming around on this, which is great. Will institutions respond by investing in methods expertise?

🚨 Next month, we’ll be hosting a one-day event on target-trial emulation and other frameworks, exploring the role and potential of observational data for evaluating the effects of interventions Open to everyone working in #datascience #biostatistics #clinicaltrials Get your ticket 🔽 bit.ly/TTE_25

Private meeting: conclave Public meeting: convlex

I’d counter by having pensioners sent to classes on climate change, trade economics and the histories of slavery and colonialism. Two can play at this game.

The problem with this study is not confounding. The problem is that it is a meaningless 'risk factor association study'. The results cannot be interpreted. The study has zero scientific or practical value. Such studies need to be outlawed for undermining faith in science.

HIRING! We offer 3 fully funded PhD positions to work on research methodology with experts in a great medical research environment. More info: www.linkedin.com/feed/update/...

“Scale vs Scrutiny” beautifully sums up an aspect the grey zone between statistics and data science.