Melanie Weigert
@mewe03.bsky.social
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📥 85
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Scientist. Biomarkers. Ovarian Cancer. Travel. Food. My dog. Plants.
pinned post!
What a way to start the New Year! Our manuscript on the single cell pre- and postmenopausal human fallopian tube is out!
www.nature.com/articles/s41...
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A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause - Nature Communications
The fallopian tube undergoes extensive cellular and molecular changes during the menstrual cycle and aging. Here, Weigert et al. present a single-cell atlas of the normal human fallopian tube revealin...
https://www.nature.com/articles/s41467-024-55440-2
11 months ago
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Yes, yes, yes!!!! 🙌🏻🙌🏻🙌🏻
add a skeleton here at some point
5 months ago
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reposted by
Melanie Weigert
Ronny Drapkin
8 months ago
Surprising findings of BRCA mutations on the Fallopian tubes. Result of a tremendous team effort with
@shenhui1986.bsky.social
@vainstitute.bsky.social
, Chuck Drescher
@fredhutch.bsky.social
, and Jarrod Marto
@danafarber.bsky.social
.
@pennmedcso.bsky.social
www.nature.com/articles/s41...
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Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube - Nature Communications
The human Fallopian tube (FT) is implicated as a site of origin for pelvic serous cancers. Here the authors conduct multi-omics analysis on over 100 FTs. The results challenge the assumption that BRCA...
https://www.nature.com/articles/s41467-025-58145-2
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Looking forward to seeing you all there!
#science
#standupforscience2025
#phdchat
#postdoc
#research
add a skeleton here at some point
9 months ago
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reposted by
Melanie Weigert
Elizabeth McKenna
10 months ago
Now online in Cancer Discovery: LINE-1 ORF1p Mimics Viral Innate Immune Evasion Mechanisms in Pancreatic Ductal Adenocarcinoma - by Eunae You, David Ting, and colleagues
doi.org/10.1158/2159...
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Always enjoyed joining the syndicate talks! Excellent for early career scientist!
#Phd
#postdoc
#ovariancancer
add a skeleton here at some point
10 months ago
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Interesting, I wonder how having a supportive PI/ lab environment that actually nurtures postdocs and having a lab that is well funded play into these hit publications?
#science
#academia
#phdchat
#phdforum
#postdoclife
www.pnas.org/doi/10.1073/...
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Postdoc publications and citations link to academic retention and faculty success | PNAS
Postdoctoral training is a career stage often described as a demanding and anxiety-laden time when many promising PhDs see their academic dreams sl...
https://www.pnas.org/doi/10.1073/pnas.2402053122
10 months ago
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reposted by
Melanie Weigert
Adam Grant
11 months ago
Personality is how you respond on a typical day. Character is how you show up on a hard day. It's easy to demonstrate fairness, integrity, and generosity when things are going well. The real question is whether you stand by those values when the deck is stacked against you.
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What a way to start the New Year! Our manuscript on the single cell pre- and postmenopausal human fallopian tube is out!
www.nature.com/articles/s41...
loading . . .
A cell atlas of the human fallopian tube throughout the menstrual cycle and menopause - Nature Communications
The fallopian tube undergoes extensive cellular and molecular changes during the menstrual cycle and aging. Here, Weigert et al. present a single-cell atlas of the normal human fallopian tube revealin...
https://www.nature.com/articles/s41467-024-55440-2
11 months ago
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reposted by
Melanie Weigert
Lindsey Van Haute
12 months ago
Could breast cancer survival rates be improved simply by timing treatment to a specific stage of the menstrual cycle? Mouse and human data suggest sensitivity to chemotherapy is affected by fluctuations in ovarian hormones.
www.nature.com/articles/d41...
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What is the best time of the month to treat breast cancer?
Sensitivity to chemotherapy is affected by hormonal fluctuations.
https://www.nature.com/articles/d41586-024-03847-8
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reposted by
Melanie Weigert
Elizabeth McKenna
11 months ago
Now online in Cancer Discovery: Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma - by Tanjina Kader, Jia-Ren Lin, Clemens Hug, Ronny Drapkin, Sandro Santagata, et al.
doi.org/10.1158/2159...
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reposted by
Melanie Weigert
Eric Topol
11 months ago
Generative
#AI
accuracy outperformed experts for detection of ovarian cancer via ultrasound
nature.com/articles/s41...
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International multicenter validation of AI-driven ultrasound detection of ovarian cancer - Nature Medicine
In a comprehensive dataset from 3,652 patients across 20 centers in eight countries, an ultrasound-based AI model shows robust performance across centers, ultrasound systems, 58 histological diagnoses...
https://nature.com/articles/s41591-024-03329-4
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