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stay fabulous…

Like if y'all can't behave around creators, then y'all can go watch whatever garbage there is out there. Bullying creators will just make others take a look and go "nope". This is why some of us are hesitant about making cartoons, y'all fans can't behave right.

I hate to say this, but I'd just cancel the series altogether and just leave those fans looking stupid. If people are going to bully creators, then they don't deserve the cartoon outright. And those same people are wondering why there's no new cartoons, with that Surprised Pikachu face.

everyone loved the tech industry's free music and friendship machines of 20-30 years ago. it's unclear what could be causing people to feel the opposite about the industry's new racism and insanity machine

He had the power of 7 GrandDad by his side

Wii Fit Trainer (Female): Anyone who knows anything about pizza knows that chicken is really, really good on pesto. Don't forget the cheese! Do not cut the pizza!

All life on earth has gone extinct! Vinesauce Vinny is the only survivor!

That's what I'm talking about! That's why they're everything! That's why Wizard Cookie's the goat! THE GOOOOOOOAT!!

What are your movies of this decade so far? I’ll start. 2020 - Wolfwalkers 2021 - Sing 2 2022 - Puss in Boots: The Last Wish 2023 - Nimona 2024 - The Wild Robot 2025 - Zootopia 2

Happy Birthday to Starfox as well! One of the best Nintendo series’s

Wow bullying works who would’ve thought

Last one did really well surprisingly! So I’m gonna host another one!! Here’s Sam the Salamander! Feel free if you’d like to draw her!! I’d love to see her in other styles 👀 #salamander #furry #furryart #artchallenge #punk #punkoc

BP and the rabbit toy he loathes

FREE ADOPT RAFFLE Enter to win this adorable canine ^.^ comes with 1 extra piece of art Just Follow + Like + Share to enter Ends in 24 hours #raffle #AdoptRaffle #F2E #free #lottery

The fact people who harrass creators for the direction for the shows they do is wrong and disrespectful I feel bad Goose is getting mistreated, she deserves better. It takes blood and sweat to create art and creators deserves respect

If I see anyone harassing Goose over the direction she is taking her show and her characters, it is a block on sight. Disagree if you must, but try to understand her first rather than saying something mean. She is trying harder than you know to make something wonderful, and I believe in her.

TIL I like chicken nuggies Of course I did I like anything with chicken for some reason

Happy Zelda 40th anniversary!

Pokemon FireRed Version and LeafGreen Version coming to Switch on February 27! OH MY GOD KANTO IS SO BACK ❤️😭

Fire Red 🔥 and Leaf Green ☘️ #Pokemon

Comfort within a living space

realistically how many people will notice if i put a 24 minute long night/day cycle in a ~10 minute long section

she is having a normal one during the weekly pathfinder session

!!!

sketch request for 'alt-gender swap' Miranda and Sophie

The ‘PROJECT HAIL MARY’ popcorn bucket has been revealed.

5 colored slots still available

with current vaccine programs. You can read all this and more here: • www.science.org/doi/10.1126/... • med.stanford.edu/news/all-new... • www.bbc.com/news/article... • medicalxpress.com/news/2026-02... • bioengineer.org/single-vacci... • www.yahoo.com/news/article...

response tool against emerging pandemics, bridging current gaps in vaccine development. The combination of ease of administration through nasal delivery, broad pathogen coverage, and sustained protective immunity could transform public health strategies and reduce the complexity and costs associated

treatments with a single intranasal spray administered biannually or seasonally. The potential global health impact of such a universal respiratory vaccine is profound. This technology promises to not only mitigate the burden of recurring seasonal infections but also equip humanity with a rapid-

Initial plans include Phase I safety assessments followed by controlled human challenge studies to evaluate efficacy. If successful, this vaccine could dramatically simplify vaccination regimens, replacing a patchwork of annual shots for influenza, COVID-19, RSV, bacterial pneumonia, and allergy

enables the adaptive immune system to respond with exceptional rapidity- typically within three days, a process that otherwise takes weeks- thereby preventing pathogens from gaining a foothold. Looking ahead, researchers are eager to translate these promising preclinical findings into human trials.

According to researchers, the dual-action mechanism of the vaccine provides a formidable “double whammy.” It primarily restrains viral proliferation by activating the extended innate immune response, which reduces viral titers in the lungs by an estimated 700-FOLD. Concurrently, this primed state

dampened Th2 immune responses and reduced mucus buildup in lung airways after vaccination. The capacity of the vaccine to suppress allergic inflammation points toward its utility in managing chronic respiratory conditions like asthma, which often complicate infectious disease outcomes.

infections, such as Staphylococcus aureus and Acinetobacter baumannii, underscoring its broad-spectrum potential. The protective benefits extended further into modulating harmful immune responses associated with allergen exposure. Mice subjected to house dust mite allergens showed significantly

In unvaccinated mice, these viruses caused dramatic weight loss -a sign of illness- and often death; their lungs were inflamed and full of virus. Moreover, the vaccine demonstrated protective efficacy not only against viruses but ALSO against bacterial pathogens notorious for hospital-acquired

SARS-CoV-2 and other coronaviruses for AT LEAST (not only) THREE MONTHS. Vaccinated mice showed minimal weight loss upon viral challenge, reflecting milder disease symptoms, and exhibited dramatically reduced viral loads with near absence of lung inflammation.

maintaining the innate response for weeks to MONTHS. In this study, mice were given a drop of the vaccine in their noses. Some received multiple doses, given a week apart. Each mouse was then exposed to one type of respiratory virus. With three doses of the vaccine, mice were protected against

than days. Their new vaccine, for now known as GLA-3M-052-LS+OVA, mimics the T-cell signals that directly stimulate innate immune cells in the lungs. Delivered intranasally, mimicking natural respiratory infection routes, the vaccine recruits antigen-specific T-cells into lung tissue, thereby

vaccine in 2023) illuminated a remarkable mechanism whereby T-cells, part of the adaptive immune system, sustain the activation of innate immune cells in the lung microenvironment through cytokine signaling. This prolonged innate activation expands the horizon of immune protection to MONTHS rather

temporary and nonspecific first line of defense, innate immunity acts swiftly, deploying cells like dendritic cells, macrophages, and neutrophils to neutralize invaders. However, its protective effects have been considered transient, fading within days. The team’s prior research (tuberculosis

respiratory threats. This dual engagement creates a feedback loop that not only rapidly neutralizes pathogens but sustains this protective state for extended periods. Central to the vaccine’s efficacy is its ability to invigorate the innate immune system within the lungs. Traditionally regarded as a

harnesses an innovative strategy to mimic the cellular communication signals that coordinate immune activation during infection. By synchronizing the innate and adaptive arms of the immune system, this vaccine orchestrates a durable and comprehensive defense mechanism capable of spanning multiple

game necessitates the frequent reformulation of vaccines, such as the annual influenza shot or periodic updates to COVID-19 boosters. Breaking away from this paradigm, this new vaccine developed by researchers at Stanford eschews direct mimicry of any pathogen-specific molecule. Instead, it