This morning, @isbscience.org's Dr. Mary Brunkow was awarded the 2025 Nobel Prize in Physiology or Medicine! Dr. Brunkow shares the award with Fred Ramsdell and Shimon Sakaguchi. Read the press release here: www.nobelprize.org/.../medicine.... What a tremendous honor! Congratulations!

Check out our new paper about metabolite biomarkers for frailty in mice. Age- and frailty-related metabolites are different and present sex dimorphisms www.nature.com/articles/s41... Thanks to @alicekane.bsky.social @judywbio.bsky.social & other authors

👏 Big congrats to our 2025 Data Blitz Award winners! 🏅 PostDocs: Min Hoo Kim, and Dantong Zhu 🏅 Techs/Grad Students: Mahima Devarajan, and Michaela Vance. Incredible science from rising stars! #AGEAnnualMeeting2025 #AgingResearch #DataBlitz #YoungScientists

Check out our latest preprint on the development of clocks to predict PhenoAge in mice! www.biorxiv.org/content/10.1...

Data request! Do you assess frailty index in your aging C57 mouse studies? @dantong-zhu.bsky.social is making new and improved clocks to predict age and lifespan based on frailty data & we aim to validate widely! Reach out if you want to collaborate 🐀👵⏰ Especially if you have female data + lifespan!

Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice "...In summary, our results identify sex-specific metabolite biomarkers of frailty in aging, and shed light on potential mechanisms involved in frailty" @alicekane.bsky.social www.biorxiv.org/content/10.1...

Metabolomics biomarkers of frailty: a longitudinal study of aging female and male mice https://www.biorxiv.org/content/10.1101/2025.01.22.634160v1

Check out the first publication from the Kane lab @isbscience.org! RNAseq analysis of sex differences in aging across tissues - spoiler alert - there are lots of them! bsd.biomedcentral.com/articles/10.... Congratulations and thans to @dantong-zhu.bsky.social, @judywbio.bsky.social & other authors.