#CNRSnews 📰 Although she was at the origin of the discovery of the supernumerary chromosome of trisomy 21, it took 50 years for Marthe Gautier to be recognised for her contribution to this breakthrough for which a male colleague took all the credit 🧬

Les nouvelles règles envisagées pour l'ANR sont plus qu'inquiétantes. Elles porteraient un immense coup d'arrêt à la recherche fondamentale en France, surchargeraient les jeunes chercheurs, et n'attendraient sans doute même pas leur objectif (apparent) de réduction du nombre de candidatures

Have just seen the news about updated, stricter ANR grant rules in France @agencerecherche.bsky.social . One argument is to better support teams with 'potential towards Europe', meaning European grants. I'm not sure how much sense it makes as a policy. 1/n

#ESR L'information circule beaucoup, en particulier dans le milieu des sciences expérimentales qui dépend crucialement de financements conséquents, et en particulier dans le milieu de la biologie qui a produit la création de l'ANR. Mais sans source. Elle est là: rogueesr.fr/anr-aapg-202...

#Communiqué 🗞️ Thierry Dauxois, Pdg du CNRS, nomme Sandrine Sagan directrice générale déléguée à la science du CNRS, à compter du 1er août 2026. Actuelle directrice de CNRS chimie, elle succèdera à Alain Schuhl dont le mandat s’achève fin juillet. 👉 www.cnrs.fr/fr/presse/sa...

Fin 2025 : dépensez vos ressources propres au plus vite, sinon elles seront ponctionnées. Mi 2026 : vous dépensez vos ressources propres, bande d'irresponsables, on bloque ces dépenses sinon on aura plus rien à ponctionner. La logique est imparable !

Our PhD Aanchal Mishra @origichals.bsky.social will defend this December. We'll be sad to see her go - she's been heart & soul of the team in many ways. Soon a highly recomm. *postdoc candidate* with good skills in protein biochem., crystal growth, ITC, advanced AlphaFold, passionate about science.

Happy Impact Factor Day to those who celebrate!

"Mélanie était une personne formidable, fédératrice, empathique…"

We are looking for a postdoctoral candidate with experience in display techniques to co-write a fellowship application around a research program currently being developed within the team. #postdoc #phagedisplay #antibodyengineering #proteinengineering #MSCA #ARCFellowship #CNRS

2 nouvelles offres de post-doc @cnrs.fr au CBM : - post-doc en chimie : emploi.cnrs.fr/Offres/CDD/U...

www.youtube.com/watch?v=rljL... Nous sommes tous nous, vive nous ! Nous sommes tous fous, vive nous ! Allez Areski, c'est normal... (mais putain, c'est triste aussi)

Professor David Leigh wins @rsc.org presidential election. Professor Leigh, @royalsociety.org Research Professor and Sir Samuel Hall Chair of Chemistry at @manchester.ac.uk, will be president-elect from 2026-28, when his presidential term begins. Read more ➡️ www.rsc.org/news/profess...

One for #Chemsky! Congrats @profdaveleigh.bsky.social 👑 (couldn't find a sash, so a crown will have to do 😉)

Une dernière pour la route ... adieu Areski www.youtube.com/watch?v=UV_x...

Tu sens pas le brûlé? C'est normal, je t'ai expliqué, il y a eu une explosion Et l'agitation moléculaire due à cette explosion provoque une élévation thermique suffisante pour enflammer les matières environnantes C'est alors ce qu'on appelle la combustion C'est normal www.youtube.com/watch?v=hfv2...

... Adieu Areski Dans les forêts, dans les villes en braises rouges au-dessus de la mer, sur les collines parfumées, vivait une belle bête chaude et fauve qu'on appelait le bonheur. www.youtube.com/watch?v=OcQQ...

The code for these proteins was excluded from official genome and protein counts go.nature.com/4uppKYi

2 constantes de la science française : – les coupes budgétaires, sans cesse – la parole des PDG du CNRS se libère à la fin de leur mandat On comparera Antoine Petit, râlant en 2026 devant le Sénat, et Alain Fuchs, « il y a un risque de décrochage de la recherche française », en 2017.

« Vous nous avez piqué 500 millions d’euros en deux ans » : le PDG du CNRS déplore une situation budgétaire « extrêmement compliquée »

Rapport de l'UNESCO (donnees.banquemondiale.org/indicateur/G...). Entre 1996 et 2023, 𝟩 𝘱𝘢𝘺𝘴 𝘴𝘶𝘳 𝟤𝟪 en Europe ont vu leurs investissements en recherche et développement 𝗯𝗮𝗶𝘀𝘀𝗲𝗿 en % du PIB. La Moldavie, la Biélorussie, la Roumanie, la Géorgie, l’Azerbaïdjan, la Fédération de Russie, et la 𝗙𝗿𝗮𝗻𝗰𝗲.

Investissement en R&D. Il a fallu 27 ans à 21 pays européens pour augmenter leurs dépenses en recherche et développement de 0,8 % en moyenne de leur PIB. Il faudra 30, 40, 50 ans à la France pour rattraper l’Autriche ou la Belgique!

Hi folks, I’m on the ballot for President of the @rsc.org. I’m standing because we live in post-truth times where respect for expertise & evidence can no longer be taken for granted. It’s time to push back. If that resonates, RSC members can vote here www.mi-vote.com/secure/rsc 🗳️🙏

Avec la conjoncture actuelle, les coupes budgétaires de l'État se multiplient. La recherche scientifique ne passe pas entre les mailles du filet.

A cool new study from @ahellab.bsky.social showing clear in vitro ADP-ribosylation of uridine. With contributions - amlong others - from our colleagues @ucagne.bsky.social and Guillaume @cbm-upr4301.bsky.social and a tiny bit from us.

"C'est un choix pour nos sociétés, pour l'avenir", les chercheurs du CNRS protestent après l'annonce d'une nouvelle coupe budgétaire par le gouvernement pour 2026. www.francebleu.fr/emissions/l-...

Bad publication practices in journals with bad editorial practices, like MDPI. It's been known for years…

#ChemBioParis2025 showed what an inclusive, united and vibrant European & global ChemBio community can achieve together. Huge thanks to speakers, attendees, volunteers, partners and trainees for this shared success. Something important might be taking shape next… 🧪✨

Very happy to share our collaborative project on FAM118 proteins - noncanonical sirtuins that form filaments and process NAD in human and other vertebrate cells.

SUMO interactions: the 1st of two reviews which Aanchal (@origichals.bsky.social), El Hadji, and I have recently written on non-covalent interactions of SUMO is now out. The 1st covers interactions with E1, E2, and deSUMOylating enzymes; the 2nd - on interactions with SIMs etc. - will appear soon.

How can we study target engagement and selectivity of covalent inhibitors? Which electrophilic probes are best suited to study a certain amino acid? Our study on "Profiling the proteome-wide selectivity of diverse electrophiles" is published in Nature Chemistry.(1/7) www.nature.com/articles/s41...

A big thank you to all the speakers, poster presenters, volunteers, chairs, exhibitors, sponsors, and participants who made the conference #ChemBioParis2025 such a success! @icbschembio.bsky.social @euchem.bsky.social @eu-openscreen.bsky.social #ChemBio

Feeling grateful after an extraordinary #ChemBioParis2025. Thanks to all keynotes, speakers, trainees, organizers, volunteers, sponsors, and exhibitors for uniting science and spirit in Paris. The conversations, discoveries, and friendships this week remind us why we love chemical biology. 💫🔬

I supervise an excellent postdoc who's looking for a postdoc or associate position in < 1 yr. Highly skilled in chem biol and biochem (peptide synthesis, native chem ligation, bacterial expression, purification, intein-based splicing, crystallography, interaction assays). Contact me if interested.

Excited to share our latest: we engineered the reactivity of a bacterial E1-like enzyme for ATP-driven modification of C termini. Our tool mimics the logic of peptide bond formation in biology for precision modification of proteins in vitro. 🧪https://rdcu.be/ewN7C

⚠️ Seats are going fast! #ChemBioParis2025 is almost sold out. Join the biggest event ever in chemical biology — or risk missing out. 🗓️ Oct 6–9 | Paris 🎟️ Register now: chembioparis2025.com #ChemicalBiology #ICBS2025 #ECBS2025 #ScienceConference

⏳ Imagine it’s 22:07 on June 24... You’ve got less than 2 hours to: 💳 Lock in early-bird registration 📝 Submit your abstract 🎯 Or… miss the deadline, and pay €100 more to register. ⚠️ No extensions. No second chances. Avoid the stress — do it now → chembioparis2025.com #ChemBioParis2025

🧪 Just 7 days left! Early bird & abstract deadline for #ChemBioParis2025 is June 24 (Paris time). ⚠️ No extension this time — don’t miss it. 📍 Paris | 🗓 Oct 6–9, 2025 🔗 chembioparis2025.com #ChemicalBiology #DrugDiscovery #DeadlineAlert

We have another postdoc position available to work on interplay between ADP-ribosylation and ubiquitination in regulation of genome stability. For this post expertise in cell biology is required. my.corehr.com/pls/uoxrecru...

⏳ Don’t miss out! Early bird registration for #ChemBioParis2025 closes on June 10 🐦 Secure your spot now for reduced rates and join us in Paris for an exciting scientific program! 🇫🇷 🔗 chembioparis2025.com #ChemBioEvent #ICBS2025 #ECBS2025

🎉 The #ChemBioParis2025 scientific program is now online! Check it out, register, and don’t forget to submit your abstract by June 10! 🔗 chembioparis2025.com #ChemicalBiology #ICBS2025 #ECBS2025 @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social

We are thrilled to welcome @alessiociulli.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent

A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 20th. my.corehr.com/pls/uoxrecru...

🌍 Last week of reduced fees to be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris. 💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists! 📩 Hurry to get a partnership kit: chembioparis2025.com

We are thrilled to welcome Matthew Disney at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent

We are thrilled to welcome Yimon Aye at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent

We are thrilled to welcome Daniel Nomura at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent

We are thrilled to welcome @hargrovelab.bsky.social at #ChemBioParis2025 in Paris, October 6-9, 2025. Sign up here: chembioparis2025.com – Early bird ends June 10 with reduced fees for @icbschembio.bsky.social - euchems.eu - @eu-openscreen.bsky.social - @scf-chembio.bsky.social - #ChemBioEvent

🌍 Be part of the global spotlight at #ChemBioParis2025 — the premier Chemical Biology event of 2025 at Sorbonne Université, Paris. 💼 Sponsorship starts at just €300. Showcase your brand to world-leading scientists! 📩 Get our partnership kit: chembioparis2025.com #ICBS2025 #ECBS2025 #ChemBio