AdvanCell and 48Hour Discovery team up to develop a ²¹²Pb-based peptide radiotherapeutic for gastrointestinal cancer, combining cutting-edge discovery and alpha therapy expertise. #Biotech #Innovation Read below: www.bioprocessintl.com/deal-making/...

At today's press conference, AfricaCDC senior official Yap Boum II said: "We are still monitoring the conversation with the countries, and so far there has been nothing really new on that site. So as soon as we have something new, we will let you know - maybe during the next [briefing]."

Grateful to @cambiochem.bsky.social for spotlighting my PhD work, recently published in @embomolmed.org. We're really proud of this international collaboration between a wide range of researchers and clinicians. Thanks to everyone involved! www.bioc.cam.ac.uk/news/embo-mo...

An excellent piece of investigative journalism by our talented editors Joshua Abbott and Søren Hough. Opens an interesting conversation regarding the ethics of clinical trials conducted overseas, and the implications of anti-vaccination sentiments. Read below: www.bioxconomy.com/modalities/b...

Trump administration - Babies as ‘guinea pigs’: A vaccine trial in Guinea-Bissau comes under intense scrutiny. An RFK, Jr.-linked vaccine trial in Guinea-Bissau is not cancelled, despite reports.

1/12 "Reiss is also skeptical of the reasoning for the trial put forward in the protocol. She said the argument rests on a key anti-vaccination plank – the supposed danger of aluminum adjuvants. Benn and Schaltz-Buchholzer cite “concerns […] regarding providing an aluminum-containing vaccine..

An in-depth investigative piece (titled "Babies as guinea pigs") about the deeply unethical RFK Jr-funded Danish vaccine trial in Guinea-Bissau, by @sorenhough.bsky.social & Josh Abbott It includes some rather unfiltered quotes by yours truly (I did not hold back) www.bioxconomy.com/modalities/b...

Last week, I asked a simple question: is the now world-famous Guinea-Bissau vaccine trial actually cancelled? After hours of digging and speaking to sources around the world, the answer – as far as we can tell – is no.

Loss of CTLH component MAEA impairs DNA repair and replication and leads to developmental delay https://www.biorxiv.org/content/10.1101/2025.07.23.666279v1

Below, you’ll find entries from Drug Modalities Editor Søren Hough (SH) and reporters Nnenna Ohaka (NO) and Millie Hoe (MH) as they reflect on some of their favorite news stories of the year. Read the full article below: www.bioxconomy.com/modalities/y...

I am so proud of the work our BioXconomy Modalities team — in particular, Nnenna Ohaka and Millie Hoe — did over the course of 2025. The article below is only a small sampling.

It will take some time (a few years), but this change will lead to hundreds of thousands of preventable diseases in the most vulnerable parts of the population, including deaths. I assume we'll follow this up with the introduction of universal healthcare and paid family/sick/parental leave?

Awesome collaboration with @SPJacksonGroup, @drjhujh.bsky.social, Chris Carney and Soren Hough, understanding how inherited mutations in the MEAE E3 ubiquitin ligase causes disease by compromising HR-dependent replication fork protection/restart. link.springer.com/article/10.1...

Great to see this team effort out, in which we find a new player in genome stability and a neurodevelopmental disease caused by its loss. Fantastic collaboration with @drjhujh.bsky.social and @profstewartlab.bsky.social alongside @sorenhough.bsky.social and friends in @spjacksongroup.bsky.social.

Loss of CTLH component MAEA impairs #DNArepair and replication and leads to #DevelopmentalDelay By S. Hough, S. Jackson & colleagues @cam.ac.uk @cruk-ci.bsky.social 🗞️ doi.org/10.1038/s443...

So proud to have co-authored this paper with @sorenhough.bsky.social identifying mutations in MAEA, an E3 ligase, as underlying a novel disease resulting from defective HR-dependent replication fork protection/restart 🥳 Grateful to everyone that contributed, incl. the patients & their families!

It's not every day you get to name a developmental condition! Introducing the world to DIADEM: Developmental delay and Intellectual disability Associated with DEfects in MAEA 👑 It was an honor to work with such an amazing team of scientists, clinicians, and patients/families on this paper.

This is the best piece I’ve read so far on why the Guinea-Bissau RCT, in which a proven life-saving vaccine will be deliberately WITHHELD, is unethical “When benefit is established, withholding an intervention is no longer neutral experimentation it becomes premeditated harm”

Preclinical research shows ASOs could delay retinal degeneration in juvenile Batten’s disease. BioXconomy spoke to study author Michelle Hastings about what her team’s findings could mean for the future treatment of Batten disease. Read my full article below: www.bioxconomy.com/modalities/a...

Net migration to Britain has fallen by almost 80% from its 2023 peak, according to data released on Thursday.

Instagram has become a pipeline for extremist content. Influencers like Hayden McDougall and Dylan Shane are blasting out extremist content, Nazi symbols, and hate-branded merchandise to massive audiences. The platform’s refusal to intervene is turning fringe neo-Nazism into mainstream culture.

There's a lot of conspiracy theorizing about bad actors in drug development out there — that there's some magic pill for cancer that we aren't being told about, for example. It's rightfully dismissed as nonsense.

wikipedia's data shows that AI is siphoning traffic away from the site, which is a danger to its sustainability. ironically Wikipedia is more important than ever to users who want reliable information instead of slop, and to AI companies that need it for training data www.404media.co/wikipedia-sa...

Not the main thing really but the way Mark Zuckerberg pretends to just randomly think of a recipe (while all the ingredients are already on the table) right at the start is hilarious bsky.app/profile/shac...

In a world first, a progressive multiple sclerosis patient at Nebraska Medicine was treated with an allogeneic CAR T therapy. “I'm walking. My gait is so much better,” she said. “I feel better.” You can read my full article over at BioXconomy: www.bioxconomy.com/modalities/m... #CellTherapy

A good first post might be the link to this new "about us" interview in BioXconomy. www.bioxconomy.com/innovation/n...

Signal or noise? > Making peptides a ‘staple’ of cancer treatment Making peptides a ‘staple’ of cancer treatment with Peter ‘t Hart - BioXconomy >> Comment below! #strategy #competitiveintelligence #marketing #pharmaceutical #healthcare #competitivemarketing #pharma #biotech

My comments and interview with BioXconomy www.bioxconomy.com/modalities/e...

I spoke with journalist Søren Hough at BioXconomy about RFK Jr & Jay Bhattacharya's pathetic, anti-scientific, fact-free reasons they gave for canceling mRNA vaccine R&D. "Perhaps we should not have been surprised," I said, "given their anti-vaccine activism.” www.bioxconomy.com/modalities/e...

Now that we're on a shiny new website over at BioXconomy, I figured I'd reshare some of my favorite articles I've written. First up, my editorial about how CRISPR was both essential to my PhD research and also has the potential to fuel a new eugenics movement: www.bioxconomy.com/modalities/f...

I'm a historian of anticolonialism and anarchism in the 20C. My first book, 'Anarchy or Chaos', is a biography of India's foremost anarchist activist M.P.T. Acharya, and I am currently writing a book on the Indian revolutionary movement in Europe, 1905-1918. www.hurstpublishers.com/book/anarchy...

Sur Marie Godsmith, il y a un projet de valorisation à mettre en avant en ce 1er Mai (à l'intersection entre science et anarchisme : mariegoldsmith.uk Sinon, sa fiche du Maitron est bien fournie : maitron.fr/goldsmith-ma...

I'm so glad to hear that the Marie Goldsmith Project has received a British Academy/Leverhulme Trust Small Research Grant finish the translation and annotation of "Revolutionary Syndicalism and Anarchism: Struggle with Capital and Power" (1920). mariegoldsmith.uk

The whole leaded gasoline tale is the stuff of supervillains. For four decades a small group of people knowingly poisoned the world for the sake of profit, despite knowing that safer alternatives to their product are available. In a just world Robert Kehoe has the same reputation as Josef Mengele.

The most stunning thing I learned through the series was the role of Robert Kehoe in preserving the leaded gas industry. People knew in the 1920s it was dangerous. But Kehoe had total control over the science of lead for 40 years, preventing possible regulation. en.wikipedia.org/wiki/Robert_...

The project I most enjoyed working on in 2024 was my 3-episode series on industrial chemist Thomas Midgley Jr. for QAA's "Trickle Down." It's my favorite kind of tale from history: one that's never fully told in popular accounts and has lessons for the 21st century. www.patreon.com/posts/trickl...

I wouldn't have been able to complete my PhD research without CRISPR. I think it's one of the most incredible tools in the history of the field of biology. But with great power, as they say, comes great responsibility. lifesciences.connectmeinforma.com/community/ti...

If you ever want to catch up on my writing, I try to keep my personal site updated: www.sorenhough.com/portfolio Film, science, politics, whatever else - you can find it there!

One of my favorite pieces I wrote this year was a preview of the BFI London Film Festival, published over at @ebertvoices.bsky.social. www.rogerebert.com/festivals/lo...

Really enjoyed chatting to the CosmoVerse COST Action journal club about some work I've been doing with Tim Clifton, Dan Thomas and Phil Bull on building generalised tests of gravity in cosmology. Have a look at the video, and stay tuned for some exciting updates in the next couple of months!

London Film Festival 2024 Highlights - by Soren Hough www.rogerebert.com/festivals/lo...

London Film Festival 2024 Preview - by Soren Hough www.rogerebert.com/festivals/lo...