What's $40k+ a year in unexpected publishing costs in these turbulent times! 😆😭

Super-grateful to @NIH_NINDS, our awesome team and wonderful collaborators! 🙏🏽🙏🏽 @SrutiShiva @LD_McCullough #Venu Venna @UTHealthHouston Looking forward to further refining the engineering of mitochondria-enriched EVs!

This is a fantastic manuscript! Hope all goes well with the review :) Thank you @blacoste.bsky.social for collaborating with us!

Happy to share the current version of our latest story, currently under peer review. Cool collab with @dablab.bsky.social @manickam-lab.bsky.social and others. We are not only understanding endothelial deficits in an #autism model, but now also capable of rescuing them! #16p11.2 #treatment #P2Y2

🚨 I’m hiring a postdoc for Fall 2025 with experience in microbial ‘omics data analysis and phylogenetics/genomics. Projects will be centered around ancient microbial ecology & evolution. Click here for more information: bpb-us-e1.wpmucdn.com/wp.txstate.e... Please share, thank you 🙏🏻

50d free: authors.elsevier.com/a/1l8cjcI2-9... Congrats Luis on your 1st author paper! We identified a potent mast cell-activating peptide (MP12W) that, when combined with CpG, forms a nanoparticle intranasal vaccine providing broad protection against H1 influenza. @dpmp-unc.bsky.social

Neuro-Metabolic and Vascular Dysfunction as an Early Diagnostic for Alzheimer's Disease and Related Dementias. www.biorxiv.org/content/10.1...

We were awarded a TrailBlazer R21 from NIBIB to design chaperone-mimetic polymers for ribonucleoprotein delivery. Excited to work with coIs Gerard Madlambayan and Serveh Kamrava.

Meme of the week!

WashU is accepting applications for Postdoctoral Fellowship in Diabetes & Related Metabolic Diseases (T32 DK007120). If you are eligible for T32 support (need to be a US citizen or permanent resident) and are interested in working with stem cell-derived islets, please contact me!

Happy to share our new preprint on ionic liquid coated LNPs! Purva Khare led this work in collaboration with Christine Hamadani, PhD Sara Edgecomb and Eden E. L. Tanner www.biorxiv.org/content/10.1...

@Glaivy Batsuli (Stanford) & I are track chairs for the Basic Science (& possibly translational/laboratory) sessions for @THSNA 2026 www.thsna.org/web/ Know trainees or under-represented voices (including yourself!) we should consider? #thsna2026 #thrombosis #hemostasis DM or comment below!🙏

Sleep loss is a metabolic disorder www.science.org/doi/10.1126/...

We shouldn’t ask kids what they want to be when they grow up. It encourages them to define themselves in terms of work. Who we become is not a question of career—it’s a matter of character. The highest aspiration is to be a person of generosity, integrity, humility, curiosity, and wisdom.

This week's meme of the week!

This week's meme of the week! #sciencememe

Sign the petition! Canadians: An Open Letter to Canadians: Let's Ensure Canada's Research Reflects All Canadians

Who would've thought you could play Bingo with posters? Introducing #PosterBingo for the Controlled Release Society Annual Meeting! Inspired by an idea #AssafZinger and his students had! See you in Philly! youtu.be/xMpxLsW-2QA?...

New publication out in Digestive Diseases and Sciences in collaboration with @julienguyenlab.bsky.social “Engineered Probiotic Saccharomyces boulardii Reduces Colitis-Associated Colorectal Cancer Burden in Mice” 🔗 link.springer.com/article/10.1...

A great write up on our recent work in PNAS attempting to understand metabolic drivers of sleep, led by @ncons95.bsky.social ! uknow.uky.edu/research/fue...

Important diabetes news. Unfortunately, while VX264 (Vertex's encapsulated stem cell derived islet product) has been safe in patients, the company has discontinued the trial due to insufficient function of the cells. investors.vrtx.com/news-release...

Official now! Congratulations to Dr. Purva Khare on a stellar defense earlier today! We are very proud of you and will keep rooting for your continued successes at Merck!

One more for the Science 🧪 feed!

🤯🤩 #ElectronMicroscopy #Mitochondria

Many thanks for the kind invitation, hosting and all the fantastic discussions I had with faculty at the University of Ottawa! It was wonderful finally meeting the phenomenal @blacoste.bsky.social #Julie Ouellette after years of Zoom call discussions ;) more wins and power to collaborative science!

Next #EVClub is with Tamás Visnovitz and @editbuzas.bsky.social: A ‘torn bag mechanism’ of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes) Apr 2, 11 AM EDT/17.00 CEST Need the login? Sign up: surveymonkey.com/r/EVClubISEV @isev.org

Interesting review! Blood-brain barrier dysfunction as a common feature in traumatic brain injury and Alzheimer’s disease #BloodBrainBarrier #cerebrovascular #review

In hard times, people don't want to be told to look on the bright side. They want to know you're on their side. Even if you can't help them feel better, you can always help them feel seen. The best way to support others is not to cheer them up. It's to show up.

My amazing student, Purva Khare, will defend her PhD dissertation on March 31st (more in the flier), please DM for Zoom link if you are interested in learning about her work on surface re-engineering of LNPs for drug delivery to the BBB! @DuquesnePharm @AapsDuquesne

Looking forward to presenting at NC State's SFB Biomaterials Day April 4! Still time to register (docs.google.com/forms/d/e/1F...) or submit an abstract (docs.google.com/forms/d/e/1F...)

Next #EVClub: Silvia Cappello on #EV molecular cues in human brain development pubmed.ncbi.nlm.nih.gov/39302835/ Wed March 19 12 noon EST/17.00 CET Need the login? www.surveymonkey.com/r/EVClubISEV W/Tsuneya Ikezu, #EViNS, #ISEV Extracellular Vesicles in Nervous Systems Special Interest Group

If you are attending #SFB, please consider joining our Biomaterials Network Meeting!

We welcomed candidates to UNC & DPMP for in-person recruitment last week. Our grad student hosts showed them the ropes & we capped it off with a poster symposium showcasing cutting-edge research. Huge thanks to our hosts & everyone who participated in our poster symposium!

If you are interested in glia, are in Canada (yes, Canadians have glia too), and coming to Toronto for @canacn.bsky.social, then you cannot miss our upcoming CANGlia satellite symposium! Please register and submit an abstract, we’ll see you there! 🥂

BREAKING: The University of Pittsburgh and Carnegie Mellon University has reneged on their commitment to host the @sciencewriters.org annual conference and withdrew their entire financial support. The National Association of Science Writers is now looking for a new venue, sponsors, and partners.

Looking forward to a great visit to @UTHealthHouston! Much gratitude to @LD_McCullough for inviting me! Excited to present our work on EV mitochondria delivery to the BRAINS research lab @utneurology!

@kristy-ainslie-lab.bsky.social baked delicious cupcakes for our Spring Research Symposium today! This event brings together student recruits, current students, postdocs, and DPMP staff! 😋

Very cute but is that hair gel?

Next #EVClub: "A century of evidence for highly coagulant tissue factor/activated factor VII complex-exposing EVs in body fluids" See also: doi.org/10.1182/bloo... and ashpublications.org/blood/articl... Wed 12 noon EST/18.00 CET Need the login? Sign up: surveymonkey.com/r/EVClubISEV

The #BloodBrainBarrier is again on the front page 🤩

Great talk by @julienguyenlab.bsky.social at 19th International Symposium on Recent Advances in Drug Delivery Systems (RADDS) at Univ of Utah in beautiful Salt Lake City!

The few things that bring joy these days...

Next #EVClub: Joe Brealey shines "a light on fluorescent EV dyes: Evaluating efficacy, specificity and suitability by nano-flow cytometry" isevjournals.onlinelibrary.wiley.com/doi/10.1002/... Wed Feb 26 12 noon EST/18.00 CET Need the login? www.surveymonkey.com/r/EVClubISEV #ExtracellularVesicles

Congrats George Barbery on your first author review in Small: "Biodegradable Polymers for Application as Robust Immunomodulatory Biomaterial Carrier Systems" doi.org/10.1002/smll...

This week's #EVClub features "Direct intercellular vesicle exchange between adjacent cells" www.biorxiv.org/content/10.1... With Jun Yamashita and group Wed Feb 19, 11 AM Japan, 10 AM Beijing, 1 PM Melbourne; Tuesday Feb 18, 9 PM EST Need the login? www.surveymonkey.com/r/EVClubISEV

Happy Valentine's Day! Here's a poem to celebrate. Measles are red Polio makes you blue Vaccines are safe And protect me and you ♥️🧡💛💚💙💜

Meme of the week! Here's to good data this week - we could all use the good news!