Maria N. de Menezes
@menezesnmaria.bsky.social
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reposted by
Maria N. de Menezes
Ian Parish
3 months ago
It was a privilege and a pleasure for both myself and
@menezesnmaria.bsky.social
to preview a great upcoming article in
@cp-immunity.bsky.social
by
@kamphorstlab.bsky.social
showing an unexpected inhibitory role for ICOS in exhausted CD8+ T cells.
www.cell.com/immunity/abs...
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The high (I)COSt of costimulation for exhausted T cells
ICOS agonists are being investigated for cancer immunotherapy based on the idea that they will reinvigorate exhausted CD8+ T cell anti-cancer immunity. Humblin et al. unexpectedly find the opposite—th...
https://www.cell.com/immunity/abstract/S1074-7613(25)00319-X
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