Our new algorithm PHACE: Phylogeny-Aware Detection of Molecular Coevolution, by me and Ogün Adebali (@compgenomics.bsky.social), is now published in Molecular Biology and Evolution. Many thanks to @nehircanozdemir.bsky.social for the beautiful illustration of PHACE!

Coming up on August 5 🗓️ Nurdan Kuru @nurdankuru.bsky.social shares phylogeny-aware methods for variant effect prediction. Ferdy van Geest dives into MCT8 variants & thyroid disease. Computational meets clinical! #Genetics #RareDisease #MedicalGenetics ℹ️ www.varianteffect.org/seminar-seri...

#BoG25 at home - CSHL

A gene called NOVA1 may be part of the solution to the mystery of how our ancestors evolved language. Here's my story about mice with strange squeaks. [Gift link] nyti.ms/3XuVehN 🧪

NOVA1, a neuron-specific RNA binding protein & splicing factor, likely impacted language function in human evolution. Human NOVA1 is unique (vs mammals, Neanderthals), & it changes vocalization in CRISPR’d mice! TY @NatureComms @RockefellerUniv team, collaborators @erichjarvis @asiepel labs 🧵👇