🚨 Our new #preprint is out! doi.org/10.1101/2025... We used #PerturbMap spatial functional genomics in pancreatic cancer to track tumor clone dynamics and uncover how extracellular factors like Serpine1 and Serpinb2 drive immune evasion. 🧵 (1/8)

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

Immunology will be for everyone, everywhere, everyday, from driving foundational research to reaping the benefits for health. 🌎 Immunoschool 2025 is open for anyone looking to learn more about key immunotherapy advances over the last decade. FREE TO REGISTER: www.eventbrite.com/e/internatio...

The incidence of early-onset colorectal #cancer is surging By 2030, 1/3 of all CRCs will occur before the typical recommended screening age of 50 years In this #Cell commentary, Mauri et al. discuss the potential causes 🧪- and the importance of determining "tumor age" www.cell.com/cell/fulltex...

First lab Bluesky post! Happy to share new papers: PRINT: Using Perturb-map, we show in @cellpress.bsky.social how ovarian tumors resist immunotherapy > www.cell.com/cell/abstrac... PREPRINT We developed a new technology to easily generate cell-targeted LNP-RNA > www.biorxiv.org/content/10.1...

I am so excited to share the biggest (and best) part of my #PhD in @maxreichertmd.bsky.social lab We show how inter/intra-tumoral #heterogeneity impacts plasticity and treatment resistance by using #PDAC #organoids @natureportfolio.bsky.social www.nature.com/articles/s41...

1/23 Big news for the #ObenaufLab! So excited to finally share our new study providing another puzzle piece, why immunotherapy fails in many tumors, now out in @Nature 🧵👇 www.nature.com/articles/s41...

#InterferonPower! Elewaut, @obenaufa.bsky.social &co show @ Nature that inflammatory monocytes can acquire MHC-class I from tumor cells & locally activate CD8 T cells, given that the capacity of the tumor to shut down type I #IFNs & upreg PGE2 is reverted! www.nature.com/articles/s41...

#PancreaticCancer research starter pack. 65 of 150. Room for 85 more on this 1st starter pack. Who did I miss? go.bsky.app/FDafAW