I’m 49 next week. There has been one Amendment to the Constitution in my lifetime (1992, the 27th regarding when Congress can give themself raise). In the 201 years between the Bill of Rights and the 27th, we averaged a new amendment every 12.5 years. That living document is dying from stagnation.

Even if you only have a basic understanding of microbiology and immunology, you know how true it is to say that vaccines are magic. Anyone who tells you otherwise is trying to personally profit off your ignorance.

Aaron Judge and Cal Raleigh are having seasons that people will talk about for decades. But no great player is more important to his team than Jose Ramirez is. Three Guardians have a WAR over two. He is “LeBron dragging plumbers to the NBA finals” this year.

The William Calley Most Improved Award

There may never be a better case where the chosen messenger is the message

Once again I’m reminded, trust is gained in drops and lost in buckets.

I’m becoming more and more concerned that people at high levels of public discussion cannot identify the difference between a genuinely viral conversation vs a bunch of bots making noise.

My most conspiratorial thought is that repetitive standardized tests were designed to implant controls in us using code words like Hydra did to Bucky Barnes. I feel like legions of Illinois-raised children could be activated with: A baloo is a bear, a yonker is a young man, wuzzle is to mix

Genuinely curious: is there something politically appealing about this man, or is he just the most recognizable White face that wants the job?

The AI dweebs are so stupid that even when they try to create something soulful and wistful, they fail miserably by thinking that 2002 was part of a golden age. Like wars? We had two of 'em. How about the ongoing hysteria around terrorism? How about a color-coded threat level on the nightly news?

Ben Johnson is my kind of psycho. He’s like the if the Harbaughs had a feral child.

Says CSIS, "the sudden decline in right-wing terrorism is both more striking and harder to explain" but actually it's not; right-wing kidnappings and attacks on civilian transports have increased dramatically but aren't categorized as "terrorism" because they now occur under the aegis of the state.

Evergreen

Performative males come in all shapes and sizes

Magic cure-all medbeds do not exist. The only “magic” we have in medicine is vaccines, and these idiots can’t demonize them fast enough.

the three genders

I rarely take care of the sick and dying; it’s a benefit of being a pediatric ortho. On those occasions when a child with a severe MSK infection ends up in the ICU, hanging on by a thread, I cannot begin to express the devastation it causes. Vaccine hesitation will cause this on a massive scale.

Over the second four-year Trump term, 88 children will die EVERY HOUR from lack of access to American foreign aid that was available the day he arrived. Gift: www.nytimes.com/2025/09/20/o...

Lots to hate about this Fox News graphic. But, the thing that exemplifies their commitment to be careless with the truth is the use of the Staff of Hermes (the two snake caduceus) when they almost certainly meant to use the Rod of Asclepius (the one snake caduceus, and the int’l symbol of medicine)

The good news is that if a Democrat ever wins the presidency again, they will have the ability to use these sweeping powers to fix the government. The hard part will be giving up those powers after getting them. May take a special type of person to handle such a responsibility.

The admin The admin without any when facing pushback any resistance

Tapping the sign until my finger is broken

1. Put this man in the Hall of Fame already 2. What a GOAT human being

Tired: spending hundreds on trying to get maybe $12 of fruits and vegetables to grow for a small portion of one season Wired: Spending $12 dollars on herb seeds to get a never ending supply of fresh herbs. "Too much basil? Never heard of her."

Talk Of Fascism Dangerous, Warns Ministry Of Compliance

Now, at Taco Bell, with every order of any size Mountain Dew Baja Midnight™ you can get an order of our new Hepatitas for just $1.99 (a $3.99 value)

My favorite question for Centrists: "What are the indelible beliefs of centrism?" For example, as someone who identifies as a Leftist, I believe in equal rights for all, bodily autonomy, strong unions/workers rights, government regulation of industry, etc. What are their core beliefs?

Until recently, the "Saturday Night Massacre" was widely considered the darkest day in the modern US democracy experiment. The Supreme Court and, eventually, senators from Nixon's party held the line. It now seems like an HOA spat compared to what we have seen in the last 8 months.

I never, ever want to hear them complain about qualifications ever again

An answer for everyone who asked, “Why did Biden pardon Dr Fauci, Gen Milley, Liz Cheney (and other members of the select committee), etc if they did nothing wrong?”

In my new practice, I will be choosing to protect my infant and vulnerable patients from vaccine-preventable illnesses, by establishing a policy that states all vaccine-elligible patients must be vaccinated. If that upsets the raw milk demo, and I lose some patients, so be it.

Ask yourself if this is the kind of country you want to live in

This person votes. Do you?

You: Man I’m not sure I can take another bleak story in the timeline Me: What if I told you the comedian whose dad was a NY firefighter killed on 9/11 is doing a comedy tour funded by the family that *allegedly* bankrolled the attack and continues to use every remedy to block victims’ families

As Prof Wang mentions, every reason why a pregnant woman might take Tylenol (fever, infection, a significant amount of pain) is a potential stressor to a fetus and is in itself a potential risk factor for autism. In the available literature, it is not possible to assign any role to only Tylenol.

NEW WIRED led the way in reporting on Elon Musk's efforts to dismantle the US government. My colleagues and I spoke to 100s of employees at dozens of agencies to understand what happened. This is the definitive story of DOGE as told by those who experienced it www.wired.com/story/oral-h...

I mean

The suspense is killing me.

In “simple bone surgeon land,” this is akin to why CRP >>>>> ESR when evaluating MSK infections. CRP is FedEx ESR is pony express

Consumer boycotts work. They worked against Disney. Fallon never recovered after his ridiculous softball September 2016 Trump interview. He went from being number one in the ratings to dead last. It seems trite to use consumerism to punish the corporations for supporting Trump, but it works.

Tylenol. Vaccines. The data is there proving both safety and effectiveness. Tiny studies with poor methods that cannot be reproduced should never, ever be considered on the same level as larger, more scientifically sound studies.

I'm telling you that that world doesn't exist. Either we're all safe, or none of us are safe. Kimmel and Colbert and jokes cannot save you from what's coming. You need the people that you won't fight for, to fight for you. But one-way solidarity ain't it.

Every time I talk with @mclem.org about the economics of immigration, I come away a whole lot smarter. You can enjoy the same experience: He's written a fantastic primer on what the data reveals about the effect of slashing H-1B visas. It's a banger. Read it. www.piie.com/blogs/realti...

Preview of tomorrow’s update:

Trump followed through on his plan to threaten the rest of the world with tariffs, and because China (and many other governments, as well) had backup plans, they are doing just fine. Us, on the other hand, not so much

ICE agents held a man’s five year old autistic daughter and taunted him with “Is that your daughter” in an attempt to get him to come out of the house. They were rebuffed but two days later took him from his car.

Theory: The reason that so many Conservative actors (eg Eastwood, Stallone, Costner) have such a limited acting range is that the same lack of empathy that leads to conservatism limits their ability to effectively imagine themselves in someone else’s shoes.

The United States must join the International Criminal Court