A brief summary of our recent paper: "Five mutational “fingerprints” could help predict how visible tumours are to the immune system" eurekalert.org/news-release... Link to our paper: link.springer.com/article/10.1... #Cancer #CancerResearch #Science

Our new paper is out: Five dominant amino acid substitution signatures shape tumour immunity link.springer.com/article/10.1... Thread 🧵⬇ #cancer #tumor #immunity #immunotherapy #oncology

C > U mutations generate immunogenic peptides in SARS-CoV-2 APOBEC enzymes—key players of the innate immune system—induce mutations that become fixed in viral genomes and enhance immune recognition. nature.com/articles/s41... #COVID_19 #Immunology #virus #infectiousdiseases #vaccine #Genetics

C > U mutations generate immunogenic peptides in SARS-CoV-2 @natcomms.nature.com @matemanc.bsky.social @csabapallab.bsky.social www.nature.com/articles/s41...

I C U mutant! Our new paper is out! Our immune system doesn’t just fight viruses – it edits them. APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition. nature.com/articles/s41... #COVID_19

I C U mutant! Our new paper is out! Our immune system doesn’t just fight viruses – it edits them. APOBEC enzymes introduce C>U mutations that often make viral proteins easier for HLA molecules and T-cells to detect, boosting immune recognition. nature.com/articles/s41... #COVID_19

www.pnas.org/doi/10.1073/... How cancer arises: Genetics releases, plasticity creates, genetics stabilizes