🧪🧪New paper out, exploring the boundaries of data-driven drug discovery for chronic pain “Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study” @ndorms.bsky.social @ox.ac.uk advanced.onlinelibrary.wiley.com/doi/epdf/10....

Really proud of our team and colleagues who led the largest ever #realworlddata study, incl 52 databases from 18 European countries and the USA. Standing on the shoulders of giants @ox.ac.uk @ihieurope.bsky.social #EHDEN @ohdsi.bsky.social Enjoy the paper here: www.thelancet.com/pdfs/journal...

Four PhD projects advertised for October 2026 @ndorms.bsky.social @ox.ac.uk Find info and apply here: www.ndorms.ox.ac.uk/study/botnar...

New paper out today 🧪 : www.nature.com/articles/s41...

New paper out today: “Core Concepts in Pharmacoepidemiology: Multi-Database Distributed Data Networks” onlinelibrary.wiley.com/doi/10.1002/...

New paper out: the largest and most international paper to date on clustering of #longcovid patients 🧪 @ndorms.bsky.social @ox.ac.uk www.jclinepi.com/article/S089...

In Barcelona for #eular2025 ? Join us and learn some cool methods for drug repurposing @ndorms.bsky.social @ox.ac.uk

New paper out today, on the use of machine learning for causal inference @ndorms.bsky.social @ox.ac.uk - onlinelibrary.wiley.com/doi/10.1002/...

Calling all health data researchers! The abstract deadline for #OHDSIUK2025 is almost here! Submit by Friday 23 May to share your work at this leading event on real-world health data and open science.

New manuscript 4 feedback at @medrxivpreprint.bsky.social "Effectiveness of COVID-19 mRNA primary and booster vaccination against infection and hospitalisation during pregnancy: a target trial emulation and meta-analysis of data from 4 European countries" www.medrxiv.org/content/10.1... @ox.ac.uk

🚨 BREAKING 🚨 The @ihieurope.bsky.social -funded GREG project is live!! Visit our website for more details and watch this space for further news!! ihi-greg.eu

Common Ground

The 6th meeting of the Health Data Research Alliance - #OHDSI UK Special Interest Group on the #OMOP Common Data Model will be on Tuesday the 6th May at 1 pm UK time. ukhealthdata.org/events/52823/ eventbrite.co.uk/e/1317198428... @daniprietoalhambra.bsky.social

I’ve heard 100x times that + net migration EU->UK led to Brexit. I guess nobody predicted that the modification of that balance would lead to this… bbc.in/4iKVhNU

Happy Sant Jordi ‘25. Homesickness day for all of us who left Catalonia and continue to love it from the distance

New preprint awaiting feedback @medrxivpreprint.bsky.social @ox.ac.uk www.medrxiv.org/content/10.1...

A new study led by Daniel Prieto Alhambra @daniprietoalhambra.bsky.social and Junqing Xie supports the hypothesis of immunity debt showing increases of influenza rates one year after global relaxation of COVID-19 restrictions.

New paper out today “s Effect of intra-articular corticosteroid injections for knee osteoarthritis on the rates of subsequent knee replacement and post- operative outcomes: a national cohort study of England” 🧪 bmcmedicine.biomedcentral.com/counter/pdf/...

New paper out "Immunity Debt for Seasonal Influenza After the COVID-19 Pandemic and as a Result of Nonpharmaceutical Interventions: An Ecological Analysis and Cohort Study" 🧪 @ox.ac.uk @ndorms.bsky.social advanced.onlinelibrary.wiley.com/doi/epdf/10....

New paper out today in the Am J Gastroenterol 🧪 journals.lww.com/ajg/abstract... @ndorms.bsky.social @ox.ac.uk @daniellenewby.bsky.social @patripedregal.bsky.social

New Editorial paper out 🧪 “Real-world evidence for regulatory purposes: The example of DARWIN EU®” Also available in Spanish language: “Evidencias de la Vida real Para uso regulatorio: el ejemplo de DARWIN EU®” www.revistafarmaciahospitalaria.es/es-real-worl...

Nature: a reminder.. jamanetwork.com/journals/jam...

New paper out today #pacs #longcovid 🧪 www.frontiersin.org/journals/pub...

New paper out this week: “Effect of intra-articular corticosteroid injections for osteoarthritis on the subsequent use of pain medications: a UK CPRD cohort study” @nihr.bsky.social @ox.ac.uk academic.oup.com/rheumatology...

Winter in Oxford

One dead child later…

Delighted to see the final report from the Joint EC/HMA/EMA multi-stakeholder workshop on pharmacogenomics held last autumn in Amsterdam hashtag#realworldevidence hashtag#pharmacogenomics www.ema.europa.eu/en/documents...

The Pyrenees from 2 different angles

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

Cuts to NIH spending framed as saving $4 billion. But NIH funding generates returns -not just in terms of improved health- but economic returns. On average each dollar spent generates over $2 in economic activity. In MO, $800m in NIH funding supports $1.89 billion in economic activity, 8,500 jobs.

News! The public health grant has today received its first significant real-terms increase after a decade of neglect, something we - and others - have long been calling for. But it's still 26% down on 2015/16. More analysis once allocations published later.👀 www.health.org.uk/press-office...

5 disasters in 5 years..: www.bbc.co.uk/news/article...

We have two openings for UNIQ+ candidates to join us this coming summer @ox.ac.uk . Do not miss out!! www.ox.ac.uk/admissions/g...

So #covidinquiry commissioned serious research by academics at Oxford Uni into vaccine safety. Concludes “best evidence” suggests jabs saved millions of lives. And any suggestion they caused excess mortality is “low quality and has been in many cases misinterpreted.” A short 🧵

Here’s a link to the full report which is well worth a read if you’re interested in this stuff. The lead author Prof Dani Prieto-Alhambra (@daniprietoalhambra.bsky.social) gave evidence in person today and report published this evening. covid19.public-inquiry.uk/documents/in...

OHDSI UK 2024 Poster #9 "Forecasting the prescription rates of antibiotics in the UK between 2013 to 2023 incorporating the impact of COVID-19" by Marta Pineda-Moncusi et al. from @ndorms.bsky.social @daniprietoalhambra.bsky.social #OHDSIUK24 #OMOP #Posters #RWE ukhealthdata.org/wp-content/u...

Looking back at the #OHDSIUK24 meeting, we'll be sharing some of the posters over the next few days. They show the breadth and quality of OMOP-related #RWE research across the UK. (Previously posted in "the other place"). @daniprietoalhambra.bsky.social ukhealthdata.org/news/ohdsi-u...

Oxford before Christmas 🎄

Such depressing news. Kids will suffer as a result. "if I think it's dangerous" is the key here... with 'think' not being enough to inform decision making when lives are at stake www.reuters.com/world/us/tru...

¿Quieres vincular🤝 tu empresa a uno de los mayores eventos científicos🔬 a nivel internacional🌍? 👇🏽No lo dudes más y únete a @pintofscience.es, únete a #Pint25ES #Pint25

Such a pleasure examining the upcoming talent, this time as an “opponent” at @karolinskainst.bsky.social Medical Epidemiology and Biostatistics

🧪 New paper out today: "Refinement of post-COVID condition core symptoms, subtypes, determinants, and health impacts: a cohort study integrating real-world data and patient-reported outcomes" www.sciencedirect.com/science/arti...

Two friends have recently died from bowel cancer. Both relatively young. Too young to be eligible for screening, but us over 50 are not. I urge you all, if you do receive an invitation please take it up. Cancer is awful.

Feeling lucky @ox.ac.uk

Fantastic news that the government of Spain is aiming to collate scientific advise to make more evidence-based decisions. Quite a bold wise step in the right direction, particularly while other parts of the world move, pretty much, in the opposite direction ..

🧪 Out in open access, one of the first manuscripts reporting on the results from one of the DARWIN EU studies: 'Treatment of systemic lupus erythematosus: Analysis of treatment patterns in adult and paediatric patients across four European countries' @ox.ac.uk www.sciencedirect.com/science/arti...

This week at an @nihr.bsky.social meeting in London, Prof Sir Chris Whitty showed some striking data. Lots more + than -, but clearly a challenge w healh inequities and their impact on 🇬🇧 residents… lots to do!

two homes, one sound track

The dreaming spires after storm Bert @universityofoxford.bsky.social