157 House of Representatives members signed an amicus brief calling on the First Circuit to uphold a block on the NIH's planned cap on indirect cost reimbursements. Did your representative sign? In MN, only Angie Craig, Betty McCollum, and Kelly Morrison signed. endpoints.news/wp-content/u...

"FDA as we know it is finished," the agency's former commissioner lamented as the agency he once led is gutted by the new administration. Follow the developing story: endpts.com/firings-swee...

How I will remember April Fools' Day 2025. Reckless. My heart is out for these dedicated folks at NIH, FDA and CDC www.statnews.com/2025/04/01/h...

Yes! endpts.com/infectious-d...

🧵Delighted to share a new guest post by Dr Anne Toomey on **8 things scientists can do right now to stand up for science in the US** Thread of her *evidence-based* actions follows, whole post here christinapagel.substack.com/p/eight-thin... 1/11

"Though BioMarin is a global organization... the U.S. remains a vital source of innovative research that pharma companies ultimately turn into medicines. We're hoping that pipeline of good ideas, which often comes from NIH-funded research, doesn't dry out.” Thank you for your courage BioMarin.

So hoping this happens in Minneapolis standupforscience2025.org

PHAR registry study shows SELF-REPORTED medication non-adherence in PAH/CTEPH of only 6.1%. Male sex and social health determinants had largest impact. #pulmonaryhypertension #pulmsky

Community warms my heart. We have another school closure day due to negative double digit temps. Parents and pastors at my small neighborhood church just banded together to provide open gym for our kids and neighborhood kids so we don't all go insane on day 5 off of school while juggling work.

Unbelievable that device and drug reviewers and facility inspectors were cut. We need more of them, not less. Read Bottle of Lies and then tell me we should cut inspectors. Meet some advanced heart failure patients and then tell me we don't want on-time device approvals and on-market safety reviews.

When the next pandemic hits us, remember - our surveillance system did not fail - it was SABOTAGED. A quarter of the staff coordinating USDA’s National Animal Health Laboratory Network program were fired. Do not say you did not know. www.politico.com/news/2025/02...

Nice reporting by @berkeleyjr.bsky.social “Direct cost is the groceries," Golden said. "Indirect costs are the money you need to have a refrigerator and to pay your electric bill so that the milk and eggs don’t go bad.” www.nbcnews.com/health/healt...

#THT2025 #JACCHF LBCT: In patients with #heartfailure & #LVEF >40%, APTURE shunt confirmed acceptable safety profile with improvements in HF symptoms, #QoL, & functional capacity without negatively affecting right & left heart function after 2 years, regardless of PVD www.jacc.org/doi/10.1016/...

Risk score (PVD-B65) development for Group 3 PH - 42% COPD, 32% non-CPFE PF, 13% CPFE in cohort #PulmSky

As outcry builds over Trump cuts to NIH payments, drugmakers are MIA www.statnews.com/2025/02/11/n... via @statnews.com

More great reporting from @statnews.com www.statnews.com/2025/02/10/n...

The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research.

If you are pro-life, I recommend calling Congress to voice concern. Yesterday’s NIH funding cuts are likely to halt research on: - New cancer drugs - Heart attack/stroke treatment & prevention - Interventions to help premature babies survive - Mental health treatment - Etc #MedSky #NIH #research

#MedSky #EpiSky #addictionsci #policysky #polisky🧪🛟 And the brain drain begins: President of the German Max-Planck-Society states that applications from the US for science group leader positions have increased. Society will specifically target leading US researchers. www.spiegel.de/wissenschaft...

I just texted my mom

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.

Gut-wrenching. I can't believe this isn't getting shouted from the rooftops, but I guess that was the point of killing biomedical research in the US with a Friday night memo.

“Beijing assumes that Washington’s own policies will dismantle the foundations of U.S. global hegemony, even if it creates a lot of turbulence…in the process" -Yun Sun in Foreign Affairs below: www.foreignaffairs.com/china/chinas... #medsky #biosky

Thousands of FDA, CDC, HHS, NIH & other US federal health agency employees may be fired by executive order as soon as next week according to the WSJ and inside sources who spoke with them. Here's an unlocked link to the WSJ story: www.wsj.com/health/healt... #medsky #biosky

Unreal

One-quarter of Minnesota households with children are food insecure, according to a statewide huger survey by @2harvest.bsky.social. minnesotareformer.com/briefs/one-q...

Eli Lilly is dropping its Phase 2 heart failure and kidney disease drug, volenrelaxin, citing a lack of clinical benefit.

Why are way less than half of PAH patients being seen at PH centers? pubmed.ncbi.nlm.nih.gov/39836217/

My heart goes out to so many but especially to all my past colleagues that are still doing grant-funded research

Lysosome interaction with other organelles may be linked to pulmonary hypertension www.science.org/doi/10.1126/... www.science.org/doi/10.1126/... @science.org

Welcome immigrants from X interested in science to the friendlier skies of @bsky.app, as documented by a new @nature.com survey (but you already knew that 😉) "Bluesky is much better for science. There is much less toxicity, misinformation, and distractions." www.nature.com/articles/d41...

Last couple of weeks of PAH publications have some real gems, including this Chinese PAH epidemiology - great to see high-quality epi from China now being published in English pubmed.ncbi.nlm.nih.gov/39839629/

Intriguing possibility for catching PAH early - Early research but encouraging jnm.snmjournals.org/content/66/1...