Charles Lynch, PhD, and the BD² Discovery team at @weillcornell.bsky.social, in collaboration with @stanfordmedicine.bsky.social, are leveraging individualized brain imaging to map circuits and inform targeted interventions in #bipolardisorder.

We’re growing our team 🌱 Hiring a PhD/postdoc-level intern to support program ops and research coordination across a global bipolar disorder research network. From meeting prep and grant tracking to decks and newsletters, you’ll turn complex science into clear, actionable work. 🔗: bit.ly/4tlBaLO

📊 We’re sharing the largest multi‑modal psychiatric dataset—built across 6 sites with shared standards, aligned protocols & rigorous QA. The result: trusted, accessible data ready to drive new discoveries and collaborations. 🔗 www.bipolardiscoveries.org/our-work/dat...

🔍 What’s driving momentum in bipolar disorder research? At BD²’s poster session, researchers shared how studying bipolar disorder more deeply and collaboratively helps link science with real patient experience. That connection is what’s accelerating discovery. 🎥

Mental health is brain health. In STAT, Eric J. Nestler, MD, PhD, BD² Discoveries Scientific Chair, and colleagues argue that the divide between psychiatric & neurological conditions is a mistake and limits progress. Earlier, integrated approaches are key to improving lives. 🔗 bit.ly/4eLTg5S

“It’s not just about investing in bipolar research—it’s about improving care and building a community.” — @dr-altimusprime.bsky.social, PhD BD² is expanding access to data to spark ideas and drive impact for people with bipolar disorder. 📺: bit.ly/4cJpyMk

🧠 @foxmdphd.bsky.social and his BD² Discovery Research team at @mgbresearch.bsky.social are mapping brain circuits tied to specific bipolar symptoms—unlocking targeted neuromodulation treatments rather than one-size-fits-all approaches.

📊"The public release of data means more investigators, clinicians, and individuals with lived experience can start answering these questions. The time is now." - Mark Frye, MD, BD² SSC member and Integrated Network co-chair, on BD²’s first data release 🧠Learn more about the release: bit.ly/4vLaaHO

Our first public data release is live, shaped by the lived experiences of our participants. Years in the making, this dataset lays the groundwork to accelerate discovery, advance precision medicine, and support people with bipolar disorder in thriving: now and in the future. 🔗 bit.ly/4tF5f9N

📢 We're excited to welcome Erin Ross, BD²’s Director of Operations. Erin brings deep experience in science philanthropy and operations, and she will help align strategy and execution to advance bipolar disorder research. Welcome, Erin!

What’s next for addiction medicine and recovery care? Emily Baxi, PhD—BD²’s IN Program Director—joins leaders in science, policy, and patient advocacy at Hope on the Horizon. Hosted by @sciam.bsky.social Custom Media + WVU Rockefeller Neuroscience Institute April 22 | DC 🔗 luma.com/hopeonhorizon

🧬 What’s powering the next wave of bipolar disorder research? Investigators across the BD² network are exploring bioenergetics, organoids, proteomics, and new shared data—working toward a future where everyone with bipolar disorder can thrive. Hear from a few of them at our latest Poster Session. 🎥

When clinicians and researchers work together toward the goal of improving lives for those with #bipolardisorder, collaboration shifts how research progresses. Hear from Tracy Young-Pearse, PhD, on BD²'s integrated approach in the latest #InvestigatorInsights. 🧠

🔬Our network is doing amazing work! Learn more about what the CircaVent team is doing to drive discovery in #bipolar research.

Bipolar disorder research has long been slowed by fragmented data. BD²’s first Integrated Network data release helps change that, bringing together rich, longitudinal data to support more connected, collaborative discovery. 🔗See what more connected data unlocks: bit.ly/4tF5f9N

Katharina Meyer is welcoming. She's a great host & collaborates with members of the multidisciplinary CircaVent Team. They are developing brain organoids to study bipolar disorder to identify better therapeutics. Learn more about Katharina & her work in this month’s #HOWyss. #WorldBipolarDay

On #WorldBipolarDay, we've released the largest integrated dataset in psychiatry and created a new cornerstone for #bipolar research. Clinical, imaging, wearable, and biological data—combined longitudinally and standardized across sites. 🧠📈 🧪 Learn more: www.bipolardiscoveries.org/our-work/dat...

Be sure to tune in at 1pm PT/4pm ET today to hear BD² CEO Cara Altimus speak at the UCLA Brain Health Summit! www.youtube.com/live/GiUU8ge...

🧠 Women’s mental health research has historically been underfunded and underprioritized, with much of women’s health research focused on obstetrics and gynecology. This #WomensHistoryMonth, BD²’s Women’s Health Workgroup is helping close gaps by studying how bipolar disorder can differ in women.

🧠🔬Last week, 150 members of the BD² network convened for our 3rd annual Investigators Meeting. From genetics and brain circuits to whole-body health, we are uniting science and community to turn breakthroughs into improved care for people living with bipolar disorder.

What’s next in bipolar disorder research, and how do we get discoveries into care faster? We’re launching #InvestigatorInsights, a new series featuring researchers and investigators across the BD² Network. Hear from Lisa Eyler, PhD, about how BD² is moving insights into action. 🧠

Sex and gender differences in bipolar disorder have only been more clearly defined in the past two decades. This #WomensHistoryMonth, listen to Aysegul Ozerdem, MD, PhD share a snapshot of how research in women’s mental health, including perinatal bipolar disorder, has evolved. 👩‍🔬

🎥 Last month, Laureate Institute for Brain Research welcomed BD² SSC member and Integrated Network co-chair Mark Frye, MD for a lecture on precision medicine in #BipolarDisorder and depression.

Women’s mental health in Bipolar Disorder has long been underprioritized. On International Day of Women and Girls in Science, the BD² Women’s Health Workgroup explores what inclusive research can unlock and how to better support and elevate women in the field 🧠📈 🔗 bit.ly/3M4CvXT 🎬 bit.ly/3ZvwJBu

BD² joined The Conn Job podcast to talk about what’s next for #BipolarDisorder research. From brain omics and AI to large-scale collaboration, the conversation explores how psychiatry is moving beyond trial-and-error toward a more precise, data-driven future—grounded in hope 🧠📈 🎧: bit.ly/3Mm86En

📢 Milestone for bipolar disorder research! The BD² Integrated Network Longitudinal Cohort Protocol is now live: laying the foundation for the largest, most comprehensive prospective study in bipolar disorder and a new model for linking research directly to care. 📄🧪 🔗 bit.ly/451Bg1R

Great to be part of the @acnporg.bsky.social Annual Meeting last week! BD² team members and researchers joined scientists to discuss advances in precision psychiatry and neuroimaging-guided brain targeting. Proud to connect with partners advancing bipolar disorder research. 📈🧠 #ACNP2026

As we close 2025, we’re reflecting on a pivotal year built on years of research, collaboration, and commitment. We’re thankful to the global BD² community, researchers, clinicians, and participants, whose work continues to drive discovery forward 💙 #BipolarDisorder #MentalHealthResearch

What did BD² achieve in 2025? New data. Deeper partnerships. Global collaboration 🧪 Dive into our 2025 Milestone Report today! 🔗 bit.ly/496yqL7 #BipolarDisorder #Neuroscience #OpenScience #Research

We're closing out 2025 with momentum: Our milestone report captures major scientific advances across BD² programs—and the growing global community driving the work 🧪 Explore the progress shaping the future of #BipolarDisorder research. 🔗 bit.ly/496yqL7 #MentalHealth #OpenScience

🧪 Research Spotlight: @ignaciosaezphd.bsky.social of the Icahn School of Medicine at Mount Sinai will study brain activity in people with #BipolarDisorder during manic & depressive shifts 👉 Goal: Identify patterns that could guide new treatments with targeted brain stimulation. 🔗 bit.ly/4gTbBwU

On An Hour To Give, @dr-altimusprime.bsky.social and Jess Fiedorowicz, MD, PhD, join host Sam Laprade to share how BD² and @ottawahospital.on.ca are advancing scientific understanding so that all people with bipolar disorder can lead thriving lives. 📺: bit.ly/4o6dwQE Read highlights👇

🧪 Research Spotlight: Ziad Nahas, MD, MSCR, is studying how brain networks regulate mood in #BipolarDisorder & how instability drives shifts between depression & mania with PACE 👉 Goal: Test if targeting networks can improve mood & reveal mechanisms behind switches. 🔗 bit.ly/4gTbBwU

🚨 Last call! Letters of intent for BD²’s Discovery Research RFA are due this Thursday, Nov 21. 🔬 Up to $1.5M/year over 3 years 💡 Research focused on the biology of #BipolarDisorder 🔗 Apply today: bit.ly/4mtZ6tC Join a network driving discovery in bipolar science

🧪 Research Spotlight: Charles Lynch, PhD of @weillcornell.bsky.social, with @stanfordmedicine.bsky.social, is mapping mood-related brain circuits & testing how they shift in people with #Bipolar 👉 Goal: Linking brain activity to mood could open the door to precision treatments. 🔗 bit.ly/4gTbBwU

⏰ Just 2 weeks left to apply! BD² is investing up to $18M in Discovery Research to uncover the biological mechanisms of #BipolarDisorder. 🔬 Up to $1.5M/year for 3 years 📅 LOIs due Nov 21 🧠 Join a growing network driving progress in bipolar science. Apply: bit.ly/4mtZ6tC

🧪 Research Spotlight: Michael Fox, MD, PhD (@foxmdphd.bsky.social) of Mass General Brigham (@mgbresearch.bsky.social) will map brain circuits driving symptoms in #BipolarDisorder 👉 Goal: Go beyond imaging correlations to identify the circuits causing symptoms. 🔗 bit.ly/4gTbBwU

We are proud to award $18M to four new Discovery Research teams exploring neuromodulation and brain circuits in #Bipolar 🧠📈 🔗bit.ly/48M1TKP 🎙️ Hear from Daniel Pham, PhD, and the teams about their innovative projects 👇

📺 “The best antidote to stigma is people sharing their own stories.” Major General Gregg Martin, PhD, joins BD²’s Emily Baxi, PhD, Program Director, to discuss resilience, recovery, and how science and lived experience can change care for #BipolarDisorder. 🔗 Learn more: bit.ly/4nWlnkw

🧠📈 TOMORROW: Join BD²’s Daniel Pham, PhD, and Kelsey Barcomb, PhD, for a webinar answering questions on the Cycle 4 Discovery Research RFA—investing up to $18M in #BipolarDisorder research. 💡 Up to $1.5M/yr for 3 years (with possible renewal) 📅 LOIs due Nov 21 🔗 forms.office.com/r/MvBUnTUCbK

🚨 REMINDER: Next Wednesday, BD²'s Daniel Pham, PhD & Kelsey Barcomb, PhD, are hosting a webinar on the Cycle 4 Discovery Research RFA. They'll review the key information and requirements for your application. 🔗 Register: forms.office.com/r/MvBUnTUCbK

📢 Next Wednesday (October 8, 12 PM ET), BD² will host a webinar on the Cycle 4 Discovery Research RFA. Daniel Pham, PhD, & Kelsey Barcomb, PhD, will review eligibility, scope, LOI requirements, Open Science expectations, & key dates. Register now 👉 forms.office.com/r/MvBUnTUCbK

📢 Exciting update: BD² and CareEvolution have partnered to launch BD² Connect. This new digital tool supports BD² Integrated Network study participants manage EHRs, sync wearables, and engage in research that aims to improve care for #bipolardisorder. 🔗 Learn more: bit.ly/46lil2Y

🌎🧪 Apply for our open Discovery Research grants and join a network of scientists across the world who are dedicated to improving the lives of people with #bipolardisorder. 🔗 Read the RFA: bit.ly/4mtZ6tC

🚨We’re investing up to $18M in Discovery Research, dedicated to uncovering the biological mechanisms of #BipolarDisorder. 🔬 Up to $1.5M/year for 3 years per team 🧑‍💻 Applicant webinar Oct 8 📅 LOIs due Nov 21 Hear from Daniel Pham, Program Director, on what’s ahead + how to apply: bit.ly/4mtZ6tC 🧠📈

BD² is transforming science, care & outcomes for people with #bipolardisorder. 🧪 Our 2025 Progress Report shows how we’re expanding our network, advancing research & building resources to improve care. Check out the update: www.bipolardiscoveries.org/2025/08/2025...

What if #BipolarDisorder care was shaped by those living it—and powered by real-time data? 🧪 Read about how BD² Integrated Network is doing that with insights from Mark Frye, MD, Sam Savitz, PhD, and @ahvinson.bsky.social bit.ly/477P5xr

BD² leaders @dr-altimusprime.bsky.social, Katherine Burdick, PhD, and Mark Frye, MD, sat down with @morra.bsky.social on the Anxious Achiever Podcast for a conversation about the future of #bipolardisorder research. Tune in ▶️ tinyurl.com/58fxkmxt

🔬 BD² Integrated Network Program Director @emilybaxi.bsky.social recently joined @biorender.bsky.social ‬ on a panel about the state of science funding. Watch as she discusses how BD²’s funding strategically supports its priorities in #bipolardisorder research.

🔍 New in @thelancet.com: A Comprehensive Update on #BipolarDisorder Led by BD² investigator Balwinder Singh, MD, this is a must-read for those working to improve outcomes for individuals with #bipolardisorder. 📖 Read the paper: authors.elsevier.com/a/1lTurV-4XS... ▶️ Hear from Balwinder Singh, MD: