How does your brain filter out the noise and focus enough to learn efficiently? In our newest preprint, we use intracranial recordings + computational modeling to explore how selective attention shapes learning and state representations in the human brain 🧠 www.biorxiv.org/content/10.6... 1/🧵

“What the technology allows us to do… is to decouple the invasiveness of the surgery from the total amount of information that you can exchange with the brain.” Full conversation with Ben Rapoport of @precisionneuro.bsky.social on the Juan Benet Podcast >>> bit.ly/49puuoC

So happy to see @christinamaher.bsky.social recognized by the Icahn School of Medicine at Mount Sinai with the Award for Outstanding Research in Neuroscience AND the Hausfeld Award honoring an exceptional PhD student! 🎉 Read more about Christina’s journey & all the 2026 awardees: icahnhonors.com

How do scientists measure memory? Unlike mood, memory has objective “ground truth” - you either saw it before or you didn’t. Nicole Rust explains why that makes memory easier to study across species. linktr.ee/neuroscience... #Memory #Neuroscience

Congratulations to the Icahn Mount Sinai Class of 2026! 🎓🥳 A special shout-out to Drs. Qi Xiu Fu and Christina Maher on their hooding. Watching Qi Xiu and Christina grow into exceptional researchers and mentors has been a joy.

Excited to share new work now published in @cp-iscience.bsky.social Using single-neuron recordings in humans, we show that dopamine neurons encode reward expectations derived from past experience––giving us a new look into how reward learning unfolds in the human brain 🧵👇

Excited to be attending #SOBP2026 with my incredible team of trainees. Join us on the poster floor to learn about our current projects!

Excited to launch a new podcast on the future of neurotech, computing, intelligence, and more. First guest: @maxhodak.bsky.social founder & CEO of @science.xyz building PRIMA, a retinal prosthetic restoring meaningful vision for patients with AMD. www.youtube.com/watch?v=24CM...

We are bridging the gap between real-time brain function and the molecular mechanisms that drive it. Molecular insights into neurotransmission offer a major step toward precision treatments for psychiatric and neurological conditions. www.nature.com/articles/s41...

Thanks to @onemindorg.bsky.social for consistently championing the importance of community. Whether in the lab or through the arts, the power of connection is vital to transforming mental health care.

Grateful for the opportunity to start two new collaborations through the #FBIScholars awards. These projects use a cross-species approach to explore mechanisms underlying human brain states and cognition. Thank you to the Nash and Friedman families for empowering boundary pushing neuroscience! 🧠✨

Massive congratulations to Dr. @christinamaher.bsky.social on a brilliant defense! 👏 Christina is a force of nature, and her work is incredibly exciting. It’s been a true joy to co-mentor her alongside @angelaradulescu.bsky.social. Stay tuned for Christina’s papers dropping soon! 🎓🚀

Ethics isn't a "side-project," it's the foundation of responsible neurotech. Congratulations to Fundación Tatiana for hosting the inaugural CINET neurotech conference and facilitating these critical conversations. I’m proud to center these considerations in my work.

💡The neural mechanisms behind "aha!" moments are revealed in @natcomms.nature.com. Bridging computational neuroscience and AI, this approach offers insights into learning in biological and artificial systems. Congrats to @biyuhe.bsky.social and team! Proud to be part of this work. Learn more 👇

Thanks to Ladan Jiracek for having me on the Neural Implant Podcast! We discussed how clinical neuroscience is combining high-resolution brain recordings with sophisticated behavioral studies to provide a truly comprehensive characterization of the human brain. 🎧 Listen here: tinyurl.com/yx47525v

📆 updated for 2026! list of summer schools & short courses in the realm of (computational) neuroscience or data analysis of EEG / MEG / LFP: 🔗 docs.google.com/spreadsheets...

This conversation between @davideagleman.bsky.social & Sergey Stavisky––two influential voices in the field––is a great primer on where #BCI is headed and what breakthroughs can mean for patients. Well worth a listen for anyone following the future of Neurotech👇🏽 tinyurl.com/4nfr8e47

Exciting to see this paper out! Data shows episodic memory is dependent on a small number of precisely timed, transient, internally-generated states. Understanding these precise spatial and temporal dynamics is key to developing accurate and effective memory enhancement strategies 🧠

It's always rewarding to connect with trainees at events like #Sfn25 & #NER2025. In these conversations, more and more students are asking how to break into Neurotech—fortunately for them, the community is stepping up with great resources to help them navigate their paths 🧵1/4

✨ Program Manager Job Alert ✨ Join our Mount Sinai team in NYC to steer a multi-institutional neuroscience initiative aimed at understanding Bipolar Disorder. If you’re passionate about science, data & impact we’d love to hear from you! Learn More & Apply 👇 careers.mountsinai.org/jobs/3032351...

What does "Human-centered neural engineering and AI" mean? It means prioritizing the patient across the entire pipeline: Discovery, Design, and Delivery of neuro-engineering treatments for psychiatric disorders. Join me to discuss at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social

We are proud to award $18M to four new Discovery Research teams exploring neuromodulation and brain circuits in #Bipolar 🧠📈 🔗bit.ly/48M1TKP 🎙️ Hear from Daniel Pham, PhD, and the teams about their innovative projects 👇

How mood states shift in the brain remains one of psychiatry’s biggest mysteries. With generous support from @bipolardiscoveries.org, our @sinaibrain.bsky.social team will apply cutting-edge techniques to map these transitions—aiming to build the most precise understanding of bipolar disorder yet.

Must-read #NYBCI25 coverage by @neurotechnology.substack.com in @forbes.com. My key takeaway on cognitive BCI: Our biggest limiting factor isn't tech—it's fundamental scientific understanding. We can’t advance the tech until we define the disorder. Basic research must lead the way!

What does it take to move neuroengineering breakthroughs into real-world impact? Our workshop at @embs.org #NER25 hosted by @onemindaccelerator.bsky.social, will explore how research, startups, and investment can come together to advance mental health care. neuro.embs.org/2025/satellite-workshops/

"It takes a village!" and I'm incredibly grateful to be a part of this one. It was inspiring to witness the growing community driving cutting-edge #BCI research from the bench to real life at #NYBCI25 Here’s to building the future of #neurotechnology, together. 🧠⚡

Excited to be speaking at #NYBCI25 this weekend, alongside so many leaders in #Neurotech and #BCI. It’s rare to have such diverse perspectives in one place, and I’m looking forward to the dialogue that emerges from bringing them together to advance the field. www.nybci.com/event/2886b6...

I left the 2025 @onemindorg.bsky.social music festival feeling inspired by the advances in mental health research and awareness that, together, are cracking the future of care wide open. Proud to be part of this community alongside peers like @maryamshanechi.bsky.social & @claudialugo.bsky.social!

❤️Thank you to all of Mount Sinai’s past, present and future #PostdoctoralScholars whose hard work and dedication play a vital role in advancing biomedical research. Here, we celebrate the #SchillerLab’s Dr. @paruljain.bsky.social! #NPAW2025 Learn More about her work👉 www.teenmiso.org/post/intervi...

Big congrats to @intlbrainlab.bsky.social on two groundbreaking new papers! Based on the most comprehensive map of mouse brain activity yet, their findings show how decision-making is both widely distributed and shaped by past experience. Read more: www.thetransmitter.org/decision-mak...

What I’m reading 👉📚 A powerful & personal piece by @jacobrobinson.bsky.social (CEO @motifneuro.bsky.social) on how brain-computer interfaces could transform mental health. Honest, bold & inspiring. I encourage folks to read & subscribe. brainjacob.substack.com #BCIs #BrainComputerInterface

Data from participants with treatment-resistant depression is revolutionizing our understanding of network disorders 🧠💻 Listen to a great discussion between @crozell.bsky.social and @braininspired.bsky.social on the potential of neuromodulation as a treatment for psychiatric disorders! 🎙️

NOT TO MISS! On Sept 22, 2025, Dr. Peter Rudebeck & The Lipschultz Center for Cognitive Neuroscience invite cognitive neuroscientists to a free symposium showcasing cutting-edge research being conducted across NYC & the surrounding area. Learn More | RSVP friedmanbrain.icahn.mssm.edu/lipschultz-s...

Need reality check on where brain-computer interface technology stands today? 🧠💻 This insightful conversation from @wired.com offers an accessible and grounded introduction to the field, covering what's possible now and some of the challenges that lie ahead.

This study establishes how aperiodic activity, a ubiquitous signal linked to neural noise, develops in localized brain regions and illuminates the development of prefrontal control during adolescence in the development of attention and memory.

How is prefrontal neural activity refined as we age? Out today in @nathumbehav.nature.com‬! This study, from Elizabeth Johnson, uncovers how subtle changes in neural 'noise' impact our attention, memory, and cognition through development. Proud to have contributed! www.nature.com/articles/s41...

As we step into summer, we’re taking a moment to reflect on an amazing past year and offer a warm welcome aboard to our new lab members, @emanuelmcoleman.bsky.social‬ and Henry Asher! We’re thrilled to have you join the Saez Lab team and look forward to an exciting year ahead.

Huge news for Paradromics! 🎉 Their first human implant is a major milestone. Excited to see the Connexus Brain-Computer Interface enter clinical trials, bringing us closer to restoring motor and speech function for people with disabilities. Great coverage from @ashleycapoot.cnbc.com

Looking forward to speaking at #DES2025! I’ll be sharing insights on how brain computer interfaces are helping us advance cognitive neuroscience. www.des-show.com/agenda-sessi...

What an incredible milestone! 🎉 Proud to celebrate Dr. Arianna Neal Davis, the Saez Lab's first Ph.D. graduate! 🎓 After an exceptional defense, we wish her all the best as she embarks on completing medical school 🥼 So proud to have co-supervised this trailblazer with @xiaosigu.bsky.social

Thanks to @psypost.bsky.social for the thoughtful coverage of our work exploring the neural basis of human decision-making! Explore these findings in further detail in our paper: www.jneurosci.org/content/45/1... Learn more about our work: thesaezlab.com

Had a great conversation hosted by Dr. Josh Bederson about how our lab is revolutionizing our understanding of the brain with intraoperative recordings. 🎞️ Watch to learn how our lab is advancing translational & cognitive neurosciences & neurotechnology: vimeo.com/1079556842/7...

Unlocking the brain's potential 🔐 Our research investigates how activities like meditation influence human brain activity, revealing pathways for noninvasive neuromodulation. Thanks to Yoga Journal for highlighting this work. www.yogajournal.com/meditation/n...

🤔 Imagine this scenario: you are happy at your job but learn of a professional opportunity with a great salary and benefits, but at a company that you don’t know well. What would you do? (1/11)

Congratulations to Christina Maher on a successful talk at the @sinaibrain.bsky.social retreat! Thank you for sharing insights on how we are leveraging intracranial recordings to advance our understanding of the brain. Job well done! 🎉 Learn more www.thesaezlab.com

Enjoyed very stimulating ⚡ conversations alongside @urutisha.bsky.social & @suthanalab.bsky.social at #COSYNE2025 about the future of systems & computational human neuroscience using intracranial techniques! Thanks to everyone who attended the panel and visited the Saez lab posters.

A HUGE CONGRATULATIONS to @ericjnestler.bsky.social on being named Interim Dean of the Icahn School of Medicine! As we express great enthusiasm for Dr. Nestler becoming Dean & the exciting time ahead, please join us in thanking Dean Charney for his extraordinary service & commitment to Mount Sinai.

Deeply grateful for my recent visits to @riceneuro.bsky.social, @bcmhouston.bsky.social, and @motifneuro.bsky.social! The passion for innovation and collaboration in the neuroscience research community is truly inspiring. Thanks for the opportunity to share the ongoing projects from our lab!

Going deep on the neuromodulatory potential of meditation 🧘 🧠 Thanks to @averyhurt.bsky.social at @discovermag.bsky.social for discussing how neural activity and brain states can be willfully modulated through #meditation. Read more: www.discovermagazine.com/mind/meditat...

With support for mental health research under threat, clear communication is key to securing public understanding and support. Thanks @ericjnestler.bsky.social, @karlakaun.bsky.social & Omar Abubaker for this insightful piece in @thetransmitter.bsky.social