The UK roadmap: it sounds good - but will it work? If the aim really is to replace animal experiments, then it will not work without much more attention to phase-out measures, particularly in the basic sciences. Read our blog: safermedicines.org/blog_post/th...

The Alliance for Human Relevant Science welcomes the government's roadmap to phase out animal testing. We are ready to help deliver and accelerate this vital transition. #betterscience #humanrelevant www.humanrelevantscience.org/replacing-an...

🚨 The UK needs a clear plan to end animal testing. We want to see a roadmap that is detailed and action-focused. ✍️ Sign the petition today: https://you.38degrees.org.uk/petitions/a-real-roadmap-to-phase-out-animal-testing

Film review: ‘How to make drugs and feel great about everything’ considers the science and ethics of drug development. Our verdict: Well worth watching and even funny! safermedicines.org/blog_post/ho...

The time may come when we look back and realise that animal experiments have been a huge and costly distraction, a path we might have done better to completely avoid. #betterscience #humanrelevant safermedicines.org/blog_post/mi...

👏 Don't miss this excellent commentary in @nature.com. Nonanimal methods are revolutionizing research, yet many editors, reviewers, and funders still overlook their robustness and value—leaving researchers struggling for recognition despite #NAMs’ potential to deliver better results. 🧪

Are you a researcher with an interest in human-focused #biomedical technologies? Join our upcoming Science+ meeting in London. You can also apply to present your poster at the meeting: royalsociety.org/science-even... @safermedicines.org

A brilliant paper by my brilliant colleague Pandora Pound, with a short blog to introduce it - an essential read! safermedicines.org/blog_post/ho...

In a powerful new article, Pandora Pound of @safermedicines.org uses sociologist Pierre Bourdieu’s ideas on power and legitimacy to ask why animal experimentation still dominates academia—despite scientific advances and increasing external pressure for change. 🧵 #sociology #scipol #philsci 🧪

Most animals used in experimentation are still in academic settings. Pound argues this isn’t due to scientific necessity, but because the enculturated paradigm is a powerful source of symbolic and economic capital, due to its history and systems of inertia. 2/

She explores how academics' "reluctance to relinquish their models" is a defensive tactic, given that "the animal research field is fully open to external forces and its autonomy and legitimacy are at risk as never before." 3/

Pound also calls for a rethink in how we talk about change. Rather than using “replacement” (which still treats animal experimentation as the default), she suggests “displacement” — a term that signals the intent to phase it out entirely. 4/

This shift in language matters. “Replacement” implies there’s something that must be preserved. “Displacement” reframes the goal: not to replicate animal models, but to move beyond them toward more innovative, human-relevant approaches. 5/

There's a lot to unpack here, some of which is summarized in the graphic above. Sit down with a coffee or a cocktail this weekend and give it a full read. 🔚 www.sciencedirect.com/science/arti...

The UK government promised to phase out animal testing. A promise isn't enough. We need an ambitious roadmap with firm deadlines, not more delays. Sign the petition demanding a real plan to bring UK science into the 21st century. you.38degrees.org.uk/petitions/a-...

Sign and share this petition to make sure animal testing is REALLY phased out in the UK! #betterscience #humanrelevant you.38degrees.org.uk/petitions/a-...

Defending animal research in the USA - our latest blog safermedicines.org/blog_post/ho...

Will the UK government's forthcoming strategy to reduce the use of animals in science reflect the bold developments in the US? safermedicines.org/blog_post/fd...

Patients would benefit from human-relevant science in place of preclinical animal tests that risk incorrect predictions of safety and efficacy. #betterscience #humanrelevant safermedicines.org/blog_post/on...

UK government needs to quickly up its game, or be left in the dirt by the forward-thinking US FDA, NIH and EPA, who now realise that #betterscience is #humanrelevant safermedicines.org/blog_post/as...

Vivodyne human tissues are making human-first drug testing a reality... yielding rich human data without relying on animal vivariums 👏https://www.contractpharma.com/exclusives/advantages-and-impact-of-fdas-plan-to-phase-out-animal-testing-for-mabs-and-other-drugs/

Experimental methods that don’t use animals, like tissue chips and computational models, lead to the development of safer and more effective therapies and pharmaceuticals. #betterscience #humanrelevant utahnewsdispatch.com/2025/04/16/k...

“This is a lot easier than I thought!” We hear this often after our workshops. And it's true #organonchip doesn't need to be complicated as long as you start with the small questions & increase complexity with time. The video shows our Online Academy, an e-learning platform for learning #ooc tech.

[𝐍𝐞𝐰 𝐛𝐥𝐨𝐠] Only ~10% of drugs have been tested for safety in pregnant women, risking unexpected side effects. In collaboration with esqLABs, Bayer & Placenta Lab we developed an #organonchip platform to study if small molecules can cross the blood-placenta-barrier. Read it here: shorturl.at/5gfpY

[𝐍𝐞𝐰 𝐛𝐥𝐨𝐠] The PDAC-on-Chip – A New Dimension in Pancreatic Cancer Research. Read a summary of the most important findings of our recent study with the team of Prof. Dr. Nicole Teusch at the University of Düsseldorf here: zurl.co/7pdot #drugdevelopment #cancer #spheroids #preclinic

👏 the good news we all needed! FDA announces to replace animal testing with more effective, human-relevant methods including #organonchip. Below, we've summarized the most important points. Curious about organ models? We help researchers bridge the gap between 2D cell culture and animal models.

Organ models trump traditional 2D models for studying barrier function. They recreate the complex microenvironments of specific organs and allow for a more consistent and reproducible way of measuring TEER.

Dirty tricks campaign by pro-animal research lobby in Germany www.aerzte-gegen-tierversuche.de/en/news/ques...

👏❤️ The “Patients are human” campaign by @keintierversuch.bsky.social amplifies the voices of those fighting serious illnesses (ex: multiple sclerosis, breast cancer, endometriosis, epilepsy, prostate Cancer, bipolar disorder,...) & opposing animal experiments. 🔗 Learn more:

Fabulous review of Rat Trap by Carla Owen of @afruk.bsky.social - thanks Carla 😀👏 Read the e-book or paperback now 🙏 open.substack.com/pub/animalfr...

@healthfoundation.bsky.social @cebmoxford.bsky.social @pscommissioner.bsky.social @patientsafetylearning.org @drug-evidence.bsky.social

Worrying trends uncovered in an analysis of 10 years of the UK's Early Access to Medicines Scheme: journals.sagepub.com/doi/10.1177/... - see also our short blog: safermedicines.org/blog_post/ac...

A short blog on our new study published in JRSM Open: safermedicines.org/blog_post/ac...

In this blog post, @dynamic42.bsky.social showcases their #OrganOnChip models for #InfectiousDisease research & discusses how these models are instrumental for unraveling infection mechanisms & developing new therapies. dynamic42.com/exploring-in... 🧪

Are desperate patients, likely unaware of the uncertainty surrounding the risk-benefit profile of fast-tracked drugs, simply a money-making machine for pharmaceutical companies? journals.sagepub.com/doi/10.1177/...

Animal tests are notoriously bad at identifying liver-toxic drugs. Now is the time to implement predictive complex in vitro models of human livers into routine drug testing #betterscience #humanrelevant www.frontiersin.org/journals/dru...

“I’m not a mouse, I’m not even a monkey,” she says. “When we are doing drug testing in animals, and then we take it into a clinical trial in humans we see a lot of drugs fail.” #betterscience #humanrelevant www.theguardian.com/environment/...

“We’re not going to be able to replace animals in biomedical research with the meager investments that federal agencies are now making.” #betterscience #humanrelevant thehighwire.com/news/house-o...

Only 10 percent of the articles analyzed presented correct statistical methodology

The time has come for a decisive shift away from animal testing and toward technologies that prioritize accuracy, facilitate precision medicine and establish more humane research practices #betterscience #humanrelevant

A proposal to use the cosmetic animal testing bans as a legislative framework to advance safety standards in other areas, including medicines. safermedicines.org/blog_post/ne...

Looking for a course to learn #organonchip technology to apply it in your own research? This blog contains a comprehensive, unbiased summary of on-site and online organ-on-chip courses, detailing the provider, content and location. Read it here --> shorturl.at/TBJjE

👋 Hello to the #science community of #bluesky, we are Dynamic42, and we are on a mission to recreate human physiology in vitro for better therapies and disease research without animal experiments. We post about news & insights around #organ-on-chip technology.

Created a starter pack focusing on disease modeling in a dish using stem cells! 🧪🔬 Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️ hPSC Disease Modeling: go.bsky.app/EpWsxNG For a good general stem cell pack go here: go.bsky.app/UTW4d7b

Hi @bsky.app! I'm the director of Science Advancement & Outreach, a division of PETA that works to push science policy, publishing, & graduate education away from the use of animals & toward human-relevant research. www.scienceadvancement.org Hear my story at www.testsubjectsfilm.com

Congratulations to the Human Cell Atlas & its 3,600 members! The consortium is leveraging its vast data to construct 18 human biological network atlases of human tissues & organs. Truly revolutionary and relevant work. #humanrelevantresearch Read more ⤵️

Working on a #StarterPack to collect researchers using human biology-based tools ( #organoids, #microphysiologicalsystems, other human-derived #invitro tools) + computational models & the orgs & accounts that promote non-animal science. Small so far, but I'm new here. Msg to add. go.bsky.app/SVWGwgu

Don't miss this new review on how patient-derived #organoids can revolutionize the game for personalized #cancer medicine. link.springer.com/article/10.1...

The newly launched Centre for Human Specific Research is awarding pilot and transition grants to accelerate the development and wider adoption of non-animal research. The deadline to apply is January 31! humanspecificresearch.org/grant-call/