New in JACS! Using NMR, we show how condensates selectively bind and localize ions following the 'law of matching water affinities', shaping condensate composition, interface potential & RNA stability. Read about it here: doi.org/10.1021/jacs.5c07295 @irissmokers.bsky.social

My last three students at Illinois. Congratulations to Dr. Joel Roberts, Dr. Nafisa Ibrahim (co-advised by @jrl-electrochem.bsky.social), and Astarte Abbott. Three amazing students with a bright careers ahead!

In the nucleus, many intrinsically disordered proteins (IDPs) form condensates. What IDP sequence features drive this behavior? We developed CondenSeq, a high-throughput approach to measure nuclear condensate formation, and applied it to ~14,000 IDPs to find out! rdcu.be/eq975

(Longish thread. Apologies) I have met many inspiring colleagues over the past few months, many of whom are in academic institutions targeted by the current administration, and many others who are about to be (the analogy to the ‘eye of Sauron’ has been invoked many times; gallows humor). 1/

Introducing Mpipi-Recharged🔥🔥🔥 Our Mpipi coarse-grained model for biomolecular condensates now includes a pair-specific electrostatic potential that improves its predictions, including for challenging charged systems—all while still treating solvent and ions implicitly pubs.acs.org/doi/10.1021/...

1/ 🚨We’re thrilled to share our latest study: "Cellular Function of a Biomolecular Condensate Is Determined by Its Ultrastructure" 🌟 www.biorxiv.org/content/10.1... How do biomolecular condensates achieve their cellular roles? It comes down to their internal structure. 🧵⬇️

Hello science bluesky! Excited to be part of The Rising Stars in Soft and Biological Matter Symposium along with so many amazing scientists! Register here to attend this virtual symposium next week! mrsec.uchicago.edu/educational-...