Nicola Zamboni
@nzamboni.bsky.social
📤 113
📥 8
📝 23
sysbio, metabolism, metabolomics
#ETH
Zurich. Free thoughts on metabolomics.blog
A long due overview of our "secret" engine:
metabolomics.blog/2026/03/how-...
#metabolomics
#lipidomics
#lcms
#compms
#masster
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How we analyze untargeted metabolomics data - yet another metabolomics club
As a lab primarily interested in metabolomics applications, our publications usually focus on the biological results and their relevance. Much more rarely do we describe the infrastructure that turns ...
https://metabolomics.blog/2026/03/how-we-analyze-untargeted-metabolomics-data/
2 months ago
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We are hiring. The geekier, the better!
jobs.ethz.ch/job/view/JOP...
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Postdoctoral Researcher - Metabolomics
https://jobs.ethz.ch/job/view/JOPG_ethz_1gSP4dmYD54u5EqbLs
5 months ago
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reposted by
Nicola Zamboni
Sara Mitri
6 months ago
Amazing dataset describing the metabolic profiles of 66 E. coli transporter knockouts by
@sulheim.bsky.social
with Peter Doubleday and
@nzamboni.bsky.social
. The tool, set up by
@lambdapp.bsky.social
and Eric Ulrich allows you to explore for yourself. Enjoy! Pre-print here:
doi.org/10.1101/2025...
add a skeleton here at some point
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reposted by
Nicola Zamboni
Snorre Sulheim
6 months ago
This project wouldn't been possible without Peter Doubleday and
@nzamboni.bsky.social
at
@imsb-eth.bsky.social
. Peter conducted >10,000 mass spec analyses 🤯. So grateful for this opportunity to team up with the best of the best in metabolomics 😍 Read more:
www.biorxiv.org/content/10.1...
#microsky
add a skeleton here at some point
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reposted by
Nicola Zamboni
Analyst
7 months ago
In the latest issue of Analyst: Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS.
#OpenAccess
from Nicola Zamboni et al
@nzamboni.bsky.social
@alaaothman.bsky.social
@ethz.ch
Read now:
pubs.rsc.org/en/content/a...
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Optimisation of electron-induced dissociation parameters for molecular annotation of glycerides and phospholipids in fast LC-MS
Electron-induced dissociation methods, particularly electron impact excitation of ions from organics (EIEIO), offer enhanced capabilities for lipid structural elucidation over traditional collision-in...
https://pubs.rsc.org/en/content/articlelanding/2025/AN/d5an00567a#!divAbstract
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1
reposted by
Nicola Zamboni
Analyst
7 months ago
Available to read now via Open Access:
pubs.rsc.org/en/content/a...
Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry Nicola Zamboni et al
@nzamboni.bsky.social
@alaaothman.bsky.social
@ethz.ch
#MassSpec
add a skeleton here at some point
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reposted by
Nicola Zamboni
Bright Giant
12 months ago
We are beyond happy to see so many contributions from the
#SIRIUScommunity
at tat
#Metabolomics2025
. Don't miss the opportunity to get in touch and gain first-hand insights how you can integrate SIRIUS into your annotation workflow.
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I've been asked about my slides on the
#ZenoTOF8600
. We uploaded the poster, which includes the data and comments, plus all key data and results at
polybox.ethz.ch/index.php/s/...
. Feel free to reshare or to ping me for more.
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8600_data
polybox - Use it as a logical memory stick, store your data on the ETH campus!
https://polybox.ethz.ch/index.php/s/cS36y4bfawPAdTH
about 1 year ago
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This was funny until I realized I am the one who has to prove it. 👀👀
add a skeleton here at some point
about 1 year ago
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reposted by
Nicola Zamboni
Nature Metabolism
about 1 year ago
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Discovery of metabolites prevails amid in-source fragmentation
Nature Metabolism, Published online: 28 February 2025; doi:10.1038/s42255-025-01239-4Discovery of metabolites prevails amid in-source fragmentation
https://bit.ly/41LxRCP
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9
reposted by
Nicola Zamboni
Pieter Dorrestein
over 1 year ago
A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs).
www.nature.com/articles/s42...
This finding was extrapolated to suggest that ISFs affect all metabolomics experiments to this degree. A counterpoint.
rdcu.be/ebFwc
1/n
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reposted by
Nicola Zamboni
Michael Witting
over 1 year ago
I'm happy to share a correspondence in
@naturemetabolism.bsky.social
in which I was involved.
#metabolomics
#lipidomics
www.nature.com/articles/s42...
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Discovery of metabolites prevails amid in-source fragmentation - Nature Metabolism
Nature Metabolism - Discovery of metabolites prevails amid in-source fragmentation
https://www.nature.com/articles/s42255-025-01239-4
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