Available to read now via Open Access: pubs.rsc.org/en/content/a... Fast, general-purpose metabolome analysis by mixed-mode liquid chromatography–mass spectrometry Nicola Zamboni et al @nzamboni.bsky.social @alaaothman.bsky.social @ethz.ch #MassSpec

We are beyond happy to see so many contributions from the #SIRIUScommunity at tat #Metabolomics2025. Don't miss the opportunity to get in touch and gain first-hand insights how you can integrate SIRIUS into your annotation workflow.

I've been asked about my slides on the #ZenoTOF8600. We uploaded the poster, which includes the data and comments, plus all key data and results at polybox.ethz.ch/index.php/s/.... Feel free to reshare or to ping me for more.

This was funny until I realized I am the one who has to prove it. 👀👀

A study using an n=1 experiment with single standards at 0V CID reported that 70% of detected ions were in-source fragments (ISFs). www.nature.com/articles/s42... This finding was extrapolated to suggest that ISFs affect all metabolomics experiments to this degree. A counterpoint. rdcu.be/ebFwc 1/n

I'm happy to share a correspondence in @naturemetabolism.bsky.social in which I was involved. #metabolomics #lipidomics www.nature.com/articles/s42...