Our "Atlas of Variant Effects 2030 Roadmap" is live: zenodo.org/records/1542... 1/n

An important step towards being able to predict gene expression from DNA sequence - cooperative binding of TFs to DNA characterised at an unprecedented scale

One for the #HumanGenetics community! 🧬 @mehurles.bsky.social @hilarycmartin.bsky.social @carlanderson.bsky.social

Gene editing technology began by people studying salt marshes. Ozempic began by folks studying the venom of Gila Monsters. Support for basic science has empowered us to understand our world. Tethering it to applications health has transformed and saved countless lives.

We are happy to share our enhancer scramble story, a strategy to create hundreds of stochastic deletions, inversions, and duplications within mammalian gene regulatory regions and associate these new architectures with gene expression levels 🧵 www.biorxiv.org/content/10.1...

The Sudlow Review of the UK's health data landscape together with 5 corresponding recommendations has been released 👉 www.hdruk.ac.uk/helping-with...