New paper 🔔 Collaboration @sullivan-lab.bsky.social Marissa Gittrich led the work Klebsiella phage biology has focused almost entirely on capsulated strains, but capsule loss is the #1 resistance mechanism under phage predation. We used a naturally acapsular host to reveal the receptor landscape

🎉🥳 Preprint out 🥳🎉 Here is a work you will hear about for a while, lead by @lucasmoriniere.bsky.social in the @vivekmutalik.bsky.social's lab, we developed a workflow predicting phages receptor specifity and identifies RBP from genomes🤯 Very happy to be part of this adventure and this dream team 🥰

📣Huge preprint 🔔 Today we share something our group has been working toward for a long time, led by @lucasmoriniere.bsky.social We asked can we predict which receptor a phage targets from its genome sequence alone? For most phages, we couldn’t. So Lucas set out to do something I had only dreamed of.

Hey #microsky #microbiome nerds! My collaborator Spencer Diamond is hiring a postdoc. You get to work with a lot of awesome microbiome data, including rumen microbiome data. Spencer's a great guy to work with and has taught me a lot. aprecruit.berkeley.edu/JPF05234

One more paper about phage-host interaction! www.biorxiv.org/content/10.1... #microsky #phagesky

The host range of generalist and specialist phages in capsule-diverse Klebsiella hosts is driven by the evolvability of receptor-binding proteins @plosbiology.org from @pilardomingoc.bsky.social journals.plos.org/plosbiology/...

#microsky 🎊🎉 High resolution lineage tracking tech from Robin & Adam D team from Berkeley! 🙌 We have used this for phage-host interaction work too in the forthcoming preprint.

Awesome work from the JBD lab! Genome-wide mutagenesis of phages is so interesting and helpful! www.biorxiv.org/content/10.1...

Hey phage lovers, What do you think of the phage-fantasy paintings I've made?

Wow! Terrific work!

📣 New preprint from phagefoundry.org team 📣 What are the phage-host interactions at a strain-level scale? Here Avery (Machine Learning) and Lucas (Experimental validation), share their new workflow to predict these interactions! I am very very grateful to work with these talented scientists!

What a nice paper!

www.science.org/doi/10.1126/... Beautiful paper describing the structure of E.coli bacteriophage Bas63!

Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes - @zhangf.bsky.social go.nature.com/46OFcoj

This is really heartbreaking. So many, so many ppl suffering. 😢

NSF stopping salaries of postdocs and researchers is outrageous to say the least.

If you are in the USA, & want to do something worthwhile, call your elected official. This is damn 🚨 urgent. Do it today.

Excited to share the major work of my dissertation, out now in @currentbiology.bsky.social! We use Drosophila genetics to dissect the evolution of phage-derived toxins that were horizontally transferred to insects and now function as potent anti-parasitoid defenses (1/n): tinyurl.com/2k9ypyxr

Celebrating 🎉 holidays!