Excited to share our latest work, online today at Cell Chemical Biology, in which we determine the structure of the TRIM21-NPC molecular glue ternary complex to establish the molecular basis for nuclear pore destruction by an E3 ligase: doi.org/10.1016/j.ch...

Great piece on @corsello.bsky.social and coworkers’ exciting new discovery @stanfordmedicine.bsky.social

Great 💎s on GI cancers at #CCRTP25 @stanford-cancer.bsky.social @corsello.bsky.social -drug discovery w better yield from unexpected hits, then subsequently modified -negative results so important to publish -environmental factors like weight most likely culprits of young onset colon cancer

Excited to share our discovery of potent TRIM21 molecular glues with anticancer activity, online today @CD_AACR: "Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex". 1/18

Good morning Monterey 🌞 Nothing like multidisciplinary discussion of GI cancers to kick off another sunny morning next to the Pacific with Lipika Goyal and Pam Basto @stanford-cancer.bsky.social reviewing 8(!!) new approvals for GI cancers 🌊 Great meeting @ ANCO branch of @ascocancer.bsky.social 🤓

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55

@pollyfordyce.bsky.social @stanford-chemh.bsky.social is officially a household name. That is some real impact!

Stanford Hematology has launched a physician scientist search! Research program can be lab-based and/or translational. facultypositions.stanford.edu/en-us/job/49...

Checking out the science community on Bluesky!