@samuelmoix.bsky.social
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reposted by
Tabea Schoeler
8 months ago
π¨New preprint is out! How do genetic effects on complex traits change with age? In this work, we compare different approaches to obtain age-varying genetic effects, and show how design and modeling choices can impact the conclusions we draw.
shorturl.at/17snd
A thread π§΅π
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Design and model choices shape inference of age-varying genetic effects on complex traits
Understanding how genetic influences on complex traits change with age is a fundamental question in genetic epidemiology. Both cross-sectional (between-subject) and longitudinal (within-subject) appro...
https://shorturl.at/17snd
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reposted by
Adriaan
5 months ago
Hi
#ASHG2025
, the Lausanne team made it to Boston ! Excited to present our latest discoveries β come say hi and learn more about our research!
@samuelmoix.bsky.social
@rjhfmstr.bsky.social
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reposted by
Robin Hofmeister
7 months ago
π¨ Our parent-of-origin study is out in Nature! 𧬠Maternal and paternal alleles can have distinct β even opposite β effects on human traits, revealing a hidden layer of genetic architecture that standard GWAS miss. π
www.nature.com/articles/s41...
Highlights below!
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reposted by
Adriaan
8 months ago
Our paper, MR-link-2 has just been published! Offering pleiotropy robust Mendelian randomization from a single region!
www.nature.com/articles/s41...
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reposted by
Robin Hofmeister
9 months ago
π Hi
#ESHG2025
, the Statistical Genetics Group and alumni (
@zkutalik.bsky.social
) is coming in force!β¨ Check out our latest work on human genetics! β¨πCome see our talks & posters, or reach out to meet us!
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