Paired spatial snRNA-seq and scRNA-seq from 4 TB patients are alive at Broad Single Cell Portal, you can look up your genes in seconds :)

Evolution of splicing model architectures go.nature.com/4eweliE Figure from our recent Review: From computational models of the splicing code to regulatory mechanisms and therapeutic implications (free to read here: rdcu.be/dVNV4)

Proud to present our latest work! @tobinlab.bsky.social @wallacewly.bsky.social @gregorylab.bskyverified.social Human TB granuloma transcriptional blueprints show they are dominated by SPP1 macrophages. spp1 is essential for granuloma formation in zebrafish. journals.asm.org/doi/10.1128/...