A landmark study on the new HHGP-HK Asian cohort revealed that standard health scores like PhenoAge fall short outside European populations. Large, diverse cohorts are critical to uncovering true global disease associations and validating biomarkers for everyone. #PrecisionMedicine

Large, diverse cohorts are vital for #PrecisionMedicine. "Matching" gut #Microbiome fingerprints across 674 geographical diverse #Melanoma patients creates accurate treatment outcome predictions. These microbial markers provide a durable benchmark for #Immunotherapy success. doi.org/10.1016/j.ce...

Large diverse cohorts are the engine of #PrecisionMedicine New research using the #UCLAATLAS Biobank proves that ancestry-diverse genomic data uncovers novel disease associations, such as previously unreported risk loci. What other health critical ancestral differences await discovery?

New study in Nature shows #ImmuneAgeing starts early with T cell reprogramming and GATA3 activity. Adding antibody reactome profiling to these cohorts can reveal the extrinsic viral and environmental triggers of #Aging —a vital layer for the #MultiOmics stack. rdcu.be/fcrJT #HumanHealth

A new #HumanImmuneHealthAtlas published in Nature reveals that #ImmuneAgeing is a non-linear process starting earlier than we thought. By mapping these molecular transitions, we can better tailor vaccines and therapies to biological age, not just the clock. rdcu.be/fcrJT #Immunology #SystemsBiology

A new @cellcellpress.bsky.social study of 2,279 brain samples reveals deep molecular diversity in #Neurodegeneration. By mapping #Proteomics & PTMs, we move closer to #PrecisionMedicine and improved stratification between seemingly similar neurodegenerative diseases. www.cell.com/cell/fulltex...

New research in @natmed.nature.com reveals IgG1 producing #Bcells are key to cancer #immunotherapy success. Data from 2k+ patients show these cells coordinate with T-cells to drive anti-tumor immunity. A shift toward humoral-cellular strategies could transform outcomes. rdcu.be/e90xd

New study from #LifelinesNEXT cohort: a map of 31k+ gut viruses in mother-infant pairs. Key findings: vaginal birth & breastfeeding drive viral diversity, linked to future allergy risk. Large-scale longitudinal measurements generate unique findings for human health. doi.org/10.64898/202...

Thrilled to welcome Brian McKelligon as the new CEO of Infinity Bio! Brian's leadership will accelerate the reach of our #MIPSA technology and the inSIGHTs it delivers to researchers worldwide. Welcome to the team, Brian! #InfinityBio #AntibodyReactomics www.businesswire.com/news/home/20...

#MultipleSclerosis progression insights via #proteomic profiling: New study on MS reveals anti-viral response as a continuous disease driver, implicating #EBV infection beyond just a trigger. Highlights include sex-specific pathways for injury, repair & resilience. rdcu.be/e7ZWe #MSResearch

Infinity Bio's Katy Shaw-Saliba & Ben Larman just published a new study screening 85 Ig batches against 283,000+ viral peptides, uncovering pandemic-driven immune shifts & autoantibody changes. Discoveries like this begin with decoding the antibody reactome. doi.org/10.1002/eji....

Researchers identified proteomic markers for #LymphoidCancer risk up to 10yrs before diagnosis. This large-scale discovery reveals how early molecular signatures like sCD23 can drive risk stratification & #EarlyDetection rdcu.be/e6GBZ%E2%80%8B #Proteomics #PrecisionMedicine #Biomarkers #Lymphoma

New research in #SjogrensDisease uses salivary & serum #Proteomics to link biomarkers with #HLA alleles and autoantibodies. Large-scale, multi-omic analysis like this reveals a dynamic immune record, paving the way for high-resolution patient stratification. doi.org/10.1016/j.ar...

Groundbreaking study in @natmetabolism.nature.com uses #MultiOmics to reveal #genes & #proteins causal to #T2D. With 85% of effects tissue-specific, large-scale profiling across ancestries is key to unlocking #global therapeutic targets. rdcu.be/e4zRC #PrecisionMedicine #TranslationalResearch

New Cohort of the Week from @nataging.nature.com! By analyzing nearly 1,000 human CSF samples, researchers mapped thousands of protein changes linked to #BrainAging and AD. #Proteomics on large human cohorts set the foundation for CNS markers of an aging brain. pmc.ncbi.nlm.nih.gov/articles/PMC...

A new study in @natcomms.nature.com re-analyzed WGS data from ~750k individuals to find viral "dark matter". By mapping viral reads, researchers linked persistent #EBV to #chronicdiseases like Lupus and Dementia. Large-scale omics are key to unlocking new disease #biomarkers Article: rdcu.be/e2cAt

New study in @natcomms.nature.com: A 29-protein blood signature predicts #cancer in patients with vague symptoms. Crucially, it distinguishes malignancy from #autoimmune & infectious diseases. A vital triage tool to prioritize life-saving diagnostics. #PrecisionMedicine Read: rdcu.be/eZ6bE

A new study leverages a well characterized infant cohort to explore our #microbiome & immune health. Researchers analyzed 647 infants in the #COPSAC cohort & found environmental exposure (daycare, siblings) reduced anellovirus abundance, consistent with immune "training." #Virome #ImmuneSystem

New Nature Medicine research maps blood #biomarkers related to #aging. By analyzing 54 biomarkers related to accumulated disease over 15 years, researchers identified key "biological signatures" predictive of aging. Large cohort studies are transformative for predictive health! #geroscience

New research reveals a link between Epstein-Barr virus (EBV) & Primary Sclerosing Cholangitis. Systematic #immuneprofiling shows that #PSC associated T & B cells target #EBV, suggesting it may drive pathogenesis. www.nature.com/articles/s41... #Omics #LiverDisease #Autoimmunity #Bcell #Tcell

Great news in neurodegeneration research! Hok-A-Hin et al. used large-scale CSF proteomics on a multicenter cohort to identify new biomarkers for Frontotemporal Dementia (FTD). Importantly, identified biomarker panels distinguish FTD from Alzheimer’s in presymptomatic cases. lnkd.in/eatVVT6K

New research sheds light on the food allergy. Gill, et al. found that children with food sensitization have gE B-cells that are less mature, more diverse. This was abrogated (stopped) by having a pet dog in the first year of life, supporting the hygiene hypothesis. doi.org/10.1111/all....

Cohort of the Week: Exciting new study on a large cohort of Guillain-Barré syndrome patients. Glycolipid complex auto-antibody patterns cluster into groups linked to clinical features. A step towards personalized medicine for the diagnosis, prognosis, & treatment of GBS. doi.org/10.1093/brai...

Lupus (SLE) symptoms are notoriously varied. New research groups patients into 6 'serological subsets' based on autoantibody profiles. Links to genetic factors (NCF2, HLA) help predict specific outcomes, like blood disorders or lower rates of kidney disease. www.translationalres.com/article/S193...

Diagnosing TB in children is a persistent challenge, as sputum-based tests are often ineffective. A new study used advanced plasma proteomics to identify a non-sputum-based biosignature for TB. The identified signatures meet WHO accuracy guidelines for a pediatric TB diagnostic. Read: rdcu.be/eOtzp

Diagnosing Lyme disease in the nervous system is slow & often requires an invasive spinal tap. A new study in Nature Communications used proteomics & machine learning to identify a diagnostic protein signature in plasma, crucial progress toward a less invasive test. www.nature.com/articles/s41...

Infinity Bio, Inc. is excited to join the LoCITT trial, powering advanced antibody reactome profiling to uncover key immune signatures & improve long COVID treatment. Proud to partner with Scripps Research for remote scientific progress. #LongCovid #LoCITT #AntibodyProfiling #Immunology

A study by Ruberto et al. profiled immune responses to HERV-W retrovirus proteins in Multiple Sclerosis patients. The findings suggest pHERV-W could be a valuable biomarker for predicting MS disease progression. www.frontiersin.org/journals/imm... #MultipleSclerosis #Immunology #InfectiousDisease

A groundbreaking study in Science creates a pan-disease blood atlas using proteomic 'fingerprints.' Analyzing 8262 individuals, they identified signatures for 59 diseases, found common biological themes, & developed a model that predicted lung cancer years before diagnosis. #Proteomics #Biomarkers

For our "Cohort of the Week," we are celebrating a study by Parodis and colleagues that tackles the challenge of diagnosing Systemic Lupus Erythematosus (SLE). Read the full paper: ard.eular.org/article/S000... #Lupus #SLE #Autoimmune #Biomarkers #Diagnostics

Immune responses to common viruses may lower dementia risk. Older adults with higher antibodies to HCoV-OC43 showed better cognition and brain health, with IGDCC4 identified as a promising target for neurodegeneration prevention. www.science.org/doi/10.1126/... #Neuroscience #Alzheimers #Immunology

his week, we are inspired by groundbreaking research from the IMPACC study, published in JCI. In their paper, “A multi-omics recovery factor predicts long COVID in the IMPACC study,” Read here: www.jci.org/articles/vie... #LongCOVID #LC #MultiOmics #Biomarkers #PrecisionMedicine #IMPACC

Our "Cohort of the Week" is a study on Lupus Nephritis (LN). Researchers used immunophenotyping to find distinct immune signatures in patients that traditional methods missed, linking them to treatment outcomes. A major step toward personalized medicine for LN. Read here: www.jci.org/articles/vie...

Thrilled to announce our Early Access Grant winners: Dr. Jakob Kreye (Charité), Dr. Sergio Poli (Brigham & Women’s Hospital), & Dr. Aubree Gordon (University of Michigan). Supporting their research in autoimmune, infectious, & neurological autoimmune disorders with cutting-edge antibody profiling.

Webinar TOMORROW! 🧬 “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch

Countdown: Just a few days till the Sep 17 webinar! Hear from Katy Shaw-Saliba (Infinity Bio), Linda Kusner (GWU), Jessica Lasky-Su (Brigham/Harvard). Register: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch

Explore antibody profiling’s future! Sep 17 webinar: “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Sign up: www.labroots.com/ms/webinar/i... #Immunology #AntibodyProfiling #PrecisionMedicine #BiomedicalResearch

A new study by @thushan-desilva.bsky.social @alexjkeeley.bsky.social & colleagues provides a framework for future Streptococcus pyogenes (Strep A) vaccine development by examining the natural acquisition of humoral immunity! www.nature.com/articles/s41... #Microbiology #Pathogen #VaccineDevelopment

Just 2 weeks left! Join us Sep 17 for “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here : www.labroots.com/ms/webinar/i...

New Cohort of the Week! A groundbreaking proteogenomic study links major depressive disorder (MDD) to an increased risk for Alzheimer's disease and related dementia (ADRD). Full paper: nature.com/articles/s44... #Neuroscience #Proteomics #ADRD #Dementia #MentalHealth #Omics

New Cohort of the Week! 🧠 A fascinating study from Stanford University used proteomics & GWAS to investigate the brain barrier system's role in aging & neurodegeneration. Read the full paper: www.nature.com/articles/s41... #Neuroscience #Proteomics #GWAS #BrainHealth #Omics

Excited to announce our upcoming webinar on September 17, 2025 , “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health" Join us for a dynamic session! Register here: www.labroots.com/ms/webinar/i...

New Cohort of the Week 🧠: Maternal Immune Activation and Risk of Child Neurodevelopmental Disorders. Univ. of Copenhagen study links maternal inflammatory proteins (IL-6, VEGFA, CD5) to ADHD & autism risk at age 10. jamanetwork.com/journals/jam...

Our "Cohort of the Week" is here! We are highlighting an inspiring study on severe malaria, and how a multi-omics approach is revolutionizing our understanding of host-pathogen interactions. 🔬 #Malaria #Biomarkers www.cell.com/immunity/ful...

New #CohortOfTheWeek from Infinity Bio! Latent #EBV infection surprisingly impacts #Type1Diabetes treatment efficacy! Yale researchers found EBV-positive patients show improved responses to teplizumab. #Immunology #AutoimmuneDisease [Link: www.nature.com/articles/s41...

#CohortOfTheWeek A pivotal study on the association of anti-viral antibodies & neural autoantibodies in psychiatric disorders. Analyzing CSF/serum from patients, they found a significant link, suggesting CNS viral infection could trigger autoantibody generation pubmed.ncbi.nlm.nih.gov/40382511/

VirSIGHT™ maps the viral antibody reactome—revealing infection & vaccine history. Discover how Infinity Bio’s MIPSA-powered platform advances viral immunity research: www.infinitybio.com/wp-content/u... #ViralImmunity #AntibodyResearch #ImmunologyInnovation

Infinity Bio’s Cohort of the Week: Bos & Zambrana find inapparent DENV; Kasbergen & Koopmans track ZIKV. Multiplex serology reveals infection dynamics. www.thelancet.com/journals/lan... academic.oup.com/jid/advance-...

Our Cohort of the Week is a Danish study (British Journal of Cancer) using patient data to identify cancer prognostic biomarkers in Type 2 Diabetes. YKL-40 & CRP show promise as prognostic markers, but vary in their power based on cancer type www.nature.com/articles/s41...

🌟 Cohort Study of the Week! 🌟 From derosalab.bsky.social Gut dysbiosis linked to survival in 955 cancer patients. The balance of Akkermansia & sMAdCAM-1 are crucial for prognosis. Important #PrecisionOncology! pubmed.ncbi.nlm.nih.gov/40189749/ #CancerResearch #Microbiome #Oncology