Rianne Prins
@rianneprins.bsky.social
📤 31
📥 86
📝 2
reposted by
Rianne Prins
Sonja Billerbeck
8 months ago
Can expression of a peptide lead to antimicrobial resistance? Yes it can! We discovered this for a toxin we work with and started exploring how
#peptides
,
#antimicrobialresistance
and de-novo gene birth can come together.
@cp-trendsmicrobiol.bsky.social
Amazing work by
@rianneprins.bsky.social
add a skeleton here at some point
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reposted by
Rianne Prins
Trends in Microbiology
9 months ago
Small proteins and peptides conferring protection against antimicrobial compounds
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Small proteins and peptides conferring protection against antimicrobial compounds
The secretion of antimicrobials is widespread among microorganisms, many of which have developed protection mechanisms. While well-characterized protection mechanisms involve relatively large proteins – such as exporters or compound- or target-modifying…
http://dlvr.it/TJP46K
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Now online: can small proteins and peptides play a role in antimicrobial resistance? With
@billerbecks.bsky.social
we explore this question here:
www.cell.com/trends/micro...
@cp-trendsmicrobiol.bsky.social
For download:
www.sciencedirect.com/science/arti...
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Small proteins and peptides conferring protection against antimicrobial compounds
The secretion of antimicrobials is widespread among microorganisms, many of which have developed protection mechanisms. While well-characterized protection mechanisms involve relatively large proteins...
https://www.cell.com/trends/microbiology/abstract/S0966-842X(25)00011-3
9 months ago
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reposted by
Rianne Prins
Sonja Billerbeck
9 months ago
For yeast and fungi fans: I’ll be speaking about our work on the yeast toxicome on March 13th. Hybrid attendance possible.
www.imperial.ac.uk/events/18820...
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Imperial Fungal Science Network | Seminar Series 2025 | Seminar
A hybrid seminar program focussing on our key research themes: Biotechnology and Engineering; Ecology, Evolution and the Environment.
https://www.imperial.ac.uk/events/188201/imperial-fungal-science-network-seminar-series-2025-seminar/
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reposted by
Rianne Prins
Nature
10 months ago
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do
https://go.nature.com/41amXq2
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‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
https://go.nature.com/41amXq2
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reposted by
Rianne Prins
Sonja Billerbeck
10 months ago
Out now! We consolidated >600 Dutch yeast and characterised their activity against spoilage yeasts and relevant human and plant pathogens, focusing on yeasts that secrete antifungal proteins. Great resource for biocontrol and beyond.
pubmed.ncbi.nlm.nih.gov/39875071/
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www.nature.com/articles/s41...
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De novo designed proteins neutralize lethal snake venom toxins - Nature
Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible an...
https://www.nature.com/articles/s41586-024-08393-x
10 months ago
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reposted by
Rianne Prins
Sorek Lab
10 months ago
Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors A 🧵 1/10
www.cell.com/cell/abstrac...
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Structure-guided discovery of viral proteins that inhibit host immunity
Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify those that bind and antagonize host immune proteins. Detected proteins are shown to inhibit no...
https://www.cell.com/cell/abstract/S0092-8674(24)01478-8
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reposted by
Rianne Prins
Dirk-Jan Scheffers 🟥
about 1 year ago
New preprint from the group of
@billerbecks.bsky.social
!
add a skeleton here at some point
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