Aaah! New preprint from the Sethuraman Lab has dropped! Tamsen and I have been working on this for a while, and we can’t wait for your feedback. Short thread on our swanky new polyploid genome simulator, DemographiKs, and its functionality.

Hidden in Plain Sight. How Ks histogram dynamics can reveal and obscure ancient whole genome duplications. https://www.biorxiv.org/content/10.1101/2025.11.19.689290v1

Shout out to the #rstats {performance} package. Its check_model() function is super helpful for model evaluation. #statistics #STEM

I felt this in my bones.

Victoria Gray, the first individual to be cured of sickle cell disease with a CRISPR-based treatment, and Jennifer Doudna, #CRISPR pioneer, at the Liberty Science Center Genius Gala! 👑👑

Somewhere, something incredible is waiting to be known.

Aaah! She did it y’all! Say hello to the newly minted PhD in Evolutionary Biology from @sandiegostate.bsky.social and @ucriverside.bsky.social, Dr. Tamsen Dunn! So proud of her!

When I randomly think to myself I'd rather have root canal surgery than go through another git rebase operation 😫

Also before I broke for Spring, I worked on theoretical expectations for biases in estimates of Fst, nucleotide diversity, and Tajima’s D due to gene flow from an unsampled ghost population; and updated our 4 year old preprint and submitted it. Fun! Comments welcome.