📢 New preprint alert! We present UMIche, a modular, open-source platform to improve UMI-based molecular quantification in bulk and scRNA-seq data. → Integrated pipelines → Monomer & homotrimer UMIs → Deep learning-based simulation 🔗 doi.org/10.21203/rs....

Ever torn a tendon? Our study led by @joletmimpen.bsky.social discovered changes in fibroblast and immune cell populations that occur in quadriceps tendon tears. Read more: doi.org/10.1113/JP28... @sarahsnelling.bsky.social @adamcribbs.bsky.social

FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation https://www.biorxiv.org/content/10.1101/2025.03.06.641728v1

We are pleased to share our latest preprint: "FlowAgent: A Modular Agent-Based System for Automated Workflow Management and Data Interpretation". FlowAgent makes complex bioinformatics workflows accessible and adaptive using agentic #AI. #Bioinformatics www.biorxiv.org/content/10.1...

Oooh! Oooh! I know! Mar-a-Lago.

Bit late, but first paper of 2025. 🧬Enhancing #singlecell #transcriptomics: Our recent study introduces an interposed anchor strategy to improve gene expression profiles in droplet-based single-cell sequencing analyses. www.nature.com/articles/s42...

I was just told that I have to remove “climate” from the title of an ongoing grant if I want to keep it. And publications from that grant cannot include “climate” and other forbidden words. I can’t believe I’m writing this from the United States of America. #AcademicSky

Droplet-based sequencing is key to single-cell transcriptomics but faces challenges from bead synthesis errors. A new bead design with anchor sequences improves UMI identification, read recovery, and feature detection for both short- and long-read methods. www.nature.com/articles/s42...