Daniel Trettel
@danieltrettel.bsky.social
📤 9
đź“Ą 9
đź“ť 10
Building structure in bacteria. LANL scientist and biochemist guy.
Rare earth elements power our green tech, but their extraction is anything but “green”. Our new preprint engineered a biological alternative using protein phase separation. Full preprint:
www.biorxiv.org/content/10.6...
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Metal-Triggered Rheological Switching in Engineered Lanmodulin Condensates
Reliable recovery of rare earth elements (REEs) is increasingly important for energy and communication technologies, yet current separation methods rely on harsh chemistries and are difficult to scale...
https://www.biorxiv.org/content/10.64898/2025.12.22.696036v1.full
about 17 hours ago
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reposted by
Daniel Trettel
bioRxivpreprint
6 days ago
Metal-Triggered Rheological Switching in Engineered Lanmodulin Condensates
https://www.biorxiv.org/content/10.64898/2025.12.22.696036v1
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One step closer to designer organelles. Super excited to have been a part of this!
add a skeleton here at some point
3 months ago
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Super excited to share our work describing a widespread protein condensation system in bacteria, out in
@natcomms.nature.com
! We show that encapsulation peptides, from BMCs, independently self-assemble into liquid-like particles.
www.nature.com/articles/s41...
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A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides - Nature Communications
Bacteria are increasingly known to employ internal organization strategies. Here, authors demonstrate that bacterial encapsulation peptides cause self-condensation of associated protein domains. These...
https://www.nature.com/articles/s41467-025-62772-0
5 months ago
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Microcompartments are hard to work with, especially if you’re not one of the lucky groups with a model system. Together with
@cellforganized.bsky.social
and
@hoanghamyy.bsky.social
, we developed a toolkit for expressing alpha-carboxysomes. Don’t stress it, express it!
pubs.acs.org/doi/10.1021/...
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Robust Synthetic Biology Toolkit to Advance Carboxysome Study and Redesign
Carboxysomes are polyhedral protein organelles that microorganisms use to facilitate carbon dioxide assimilation. They are composed of a modular protein shell that envelops an enzymatic core mainly co...
https://pubs.acs.org/doi/10.1021/acssynbio.5c00144
7 months ago
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My favorite work yet! And, it came out on my birthday! Even in grad school, I knew encapsulation peptides were underappreciated. I’m thrilled to have helped give these misunderstood domains a deeper look.
add a skeleton here at some point
about 1 year ago
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Is it less weird here?
about 1 year ago
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you reached the end!!
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