The first publication while at UCLA! We developed and utilized generative AI protein design methods for targeting the disordered and highly charged C-terminus of RAS to generate RAS isoform specific binders/inhibitors: www.sciencedirect.com/science/arti...

It was such a fun journey working with Krishna’s lab and @kinasekid.bsky.social! Really excited to see where this phospho-binder technology goes!

The downfall of America

“The Party told you to reject the evidence of your eyes and ears. It was their final, most essential command.” —George Orwell, 1984 It is rare for a murder to be captured live on multiple cameras. Yet DHS persists with the obvious lie this was self defense. There are no more red lines.

Come to my talk on generative AI for biosensor design on Friday!

My lab website is now live! My lab feels a bit real now 🥺. Website: www.jasonzhanglab.com

Zara Weinberg passed away earlier this week. She joined my lab earlier this year when her postdoc lab formally closed. She was a brilliant scientist, supportive mentor, dear friend, avid music fan, rabid believer in public transit, open science champion, and above all just an amazing human.

First lab meeting at UCLA joint with @yamadahunter.bsky.social lab!

Excited to share our latest work in expanding AI-based protein design into targeting PTMs! I’m particularly excited in this work as there is so much we don’t know about PTMs despite their central role in signaling and hopefully we can start to decode their rules and functions.

Incoming from David Baker lab! New faculty at @riceuniversity.bsky.social and @uclaengineering.bsky.social with @linnaan.bsky.social and I, respectively. Last meal before we get “real world” jobs 😭.

Trump freezes $200 million in UCLA science and medical research funding, citing antisemitism

Excited to share that I’ll be joining UCLA Bioengineering as a tenure-track professor! My lab will focus on AI-driven molecular engineering to study cellular signaling. As someone 100% educated in US public schools, I’m proud to continue working in public education and inspiring future scientists!

I’ve been trying to find some reliable news about this. Are there funding cuts to NIH and NSF proposed in the Big Beautiful (really Ugly) Bill? If so, how much are the cuts?

Was so nice to meet up with @grocklin.bsky.social and talk about science! So much to learn from him. Hopefully we can be neighbors soon!

Excited to share my recent work on designing new Hsp70 activators to regulate condensates, and thus reveal their functions: www.sciencedirect.com/science/arti... @uwproteindesign.bsky.social @cp-cellchembiol.bsky.social

Very cool work from my undergrad buddy! If you are interested in virology, high throughput techniques, and biochemistry, please take a read!

I made a protein designer starter pack ⚛️👨‍💻👩‍💻! Please feel free to DM me if you want to be added. go.bsky.app/JcMhjLw

My favorite probe is the one I made: Ras activity sensors! www.nature.com/articles/s41...

We love signaling!

Just started my BlueSky account! Wondering how this will go 🤔. Will still post on my Twitter (@jasonzxzhang) as well for the time being.