A must read! I loved this paper for many reasons but I want to emphasize some meaningful terms. 1. "Pre-cancer evolution" & why it's important to understand. It dictates the full blown tumor you are trying to treat. 2. Polyclonal origin is possible! www.nature.com/articles/s41...

Finally this paper is out (my most neglected kid). Huge thanks to co-first authors, collaborators & mentor @kylie-gorringe.bsky.social. This work was selected for AACR press conference presentation at the annual meeting in 2022, followed by media & press releases. doi.org/10.1002/path...

Thanks for having me @vumedi to talk about the significance of our recent findings on HGSOC development! www.vumedi.com/video/immune...

I can't thank Claude enough for teaching and fixing my errors in R in a daily basis! 🙏🏻 And it's very polite 🤭

Even cells are smiling! 😊

Truly honored to present my post doctoral work at the #AACRovca25 last weekend at the tumor initiation plenary session. Incredibly thankful to the organizing committee for inviting me and letting me share our multi-institutional Pre-cancer Atlas work, now published in @CD_AACR.

Single-cell analysis reveals the extent of genome doubling in ovarian cancer, its variability and its role in enabling tumours to evade the immune system go.nature.com/4kJLAjZ

🚨🚨Paper out!! 🚨🚨 Excited to share our work (Pre-cancer Atlas of High Grade Serous Ovarian Cancer (HGSOC)), now published in @CD_AACR ! aacrjournals.org/cancerdiscov... What if I told you HGSOC often starts in the Fallopian Tube and progresses through precancerous lesions? 1/n 🧵👇

Everyone should watch and share. Thank you David. youtu.be/8YhJM6zxYDw

Multiplex tissue imaging 💪🏻

Surprising findings of BRCA mutations on the Fallopian tubes. Result of a tremendous team effort with @shenhui1986.bsky.social @vainstitute.bsky.social, Chuck Drescher @fredhutch.bsky.social, and Jarrod Marto @danafarber.bsky.social. @pennmedcso.bsky.social www.nature.com/articles/s41...

Very honoured to be an AACR Scholar in training awardee! Excited to talk about our pre-cancer atlas work in the plenary session of Cancer Evolution & Tumor microenvironment. @AACRJCA2025. Sunshine at Maui, Hawaii gives an incredible flavour to the meeting!

Simply Statistics: Biologists, stop putting UMAP plots in your papers https://simplystatistics.org/posts/2024-12-23-biologists-stop-including-umap-plots-in-your-papers/ from @rafalab.bsky.social 🧬🖥️🧪

This paper is the result of an incredibly fun collaboration with Sandro Santagata and Peter Sorger. Led by an amazing postdoc @tanjinakader.bsky.social and JiaRen Lin, we provide a pre-cancer atlas of Fallopian tube precursors to High-Grade Serous Ovarian Cancer. The data is also on cbioportal!

Beautiful work from my brilliant former PhD student/postdoc @tanjinakader.bsky.social and her colleagues