Julien MAMBU
@julienmambu.bsky.social
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Postdoctoral researcher
@kingscollegelondon.bsky
.social
reposted by
Julien MAMBU
FCYI
4 months ago
📣 March Article Award: Congrats to
@julienmambu.bsky.social
& team! Their Cell paper reveals type III IFNs (IFN-λ) delay gut healing by triggering pyroptosis via ZBP1 → caspase-8 → GSDMC. 🔗https://www.cell.com/cell/abstract/S0092-8674(24)01158-9
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Julien MAMBU
Joaquin Pellegrini
6 months ago
Proud to share our work! 🧫😍 A special one! Using Salmonella and Brucella, this study provides the first demonstration of an antibacterial response in pDCs orchestrated by SLAMF7 and SLAMF8, driving cytokine responses and favoring bacterial survival via mtROS control.
www.jci.org/articles/vie...
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Julien MAMBU
Achille Broggi🧪👨🏼🔬🔬
9 months ago
If you want to see our work presented directly from the primary source,
@julienmambu.bsky.social
will be giving a free webinar on Feb 6th at 5 PM CET as part of the Thursday seminar series of the French Society of Immunology
#SFI
sign up here:
zoom.us/webinar/regi...
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Julien MAMBU
Ivan Zanoni
10 months ago
#EveryCellIsAnImmuneCell!💥Thrilled
for the final version of our paper
@cp-cell.bsky.social
! We show that type III
#interferons
control ZBP1 activation driving gasdermin C cleavage & delaying gut repair by inducing
#pyroptosis
in intestinal epithelial cells! 1/n
www.cell.com/cell/abstrac...
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Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair
Intestinal damage following colitis or irradiation induces type III interferons (IFNs), which delay the healing of the intestinal epithelium. IFN-λ directs the sensing of Z-form nucleic acids generated during gut injury and repair, triggering cell death and altering healthy epithelial regeneration.
https://www.cell.com/cell/abstract/S0092-8674(24)01158-9
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Julien MAMBU
Achille Broggi🧪👨🏼🔬🔬
11 months ago
Great to have our study highlighted in
@science.org
!thanks
@smhsci.bsky.social
#interferosky
add a skeleton here at some point
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Julien MAMBU
Achille Broggi🧪👨🏼🔬🔬
11 months ago
👨🔬🎉Kicking off my bluesky presence by posting our lab's achievement! Our lab's first study is now out in Cell ! We show that IFN-λ induces ZBP1/CASP-8/GSDMC-dependent pyroptosis in gut epithelial cells impairing tissue repair post-colitis.#IBD
#Immunology
🧵https://authors.elsevier.com/a/1k2OAL7PXqSL5
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Julien MAMBU
Achille Broggi🧪👨🏼🔬🔬
11 months ago
#newlabpic
with
@julienmambu.bsky.social
, Amaury, Chloé, Sarah, Magda, Anissa, Franck, Virginie, and Thierno.
#blessed
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Julien MAMBU
Achille Broggi🧪👨🏼🔬🔬
11 months ago
Honored for our research conducted at
@ciml.bsky.social
is featured in the
@cnrs.bsky.social
biologie news. Shout out to
@julienmambu.bsky.social
for the awesome 2D
#organoids
image.
#gastrosky
#immunology
#interferon
www.insb.cnrs.fr/fr/cnrsinfo/...
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Nouvelles perspectives thérapeutiques pour les Maladies Inflammatoires Chroniques de l’Intestin
Les Maladies Inflammatoires Chroniques de l’Intestin, ou MICI, touchent plus de 250 000 personnes en France.
https://www.insb.cnrs.fr/fr/cnrsinfo/nouvelles-perspectives-therapeutiques-pour-les-maladies-inflammatoires-chroniques-de
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