I couldn't find a tool to plot different #neuroimaging data in one consistent style, so I made one! Meet yabplot (yet another brain plot) - a #Python package for (sub)cortex & tracts.🧠 - Simple API - Built-in atlases - Custom atlas support 🔗 github.com/teanijarv/ya... (drop a ⭐️!)

🩸 🧠 ⏱️ What if a blood test could predict WHEN an individual would develop symptoms of Alzheimer’s disease? High plasma p-tau217 predicts greater risk for Alzheimer’s symptoms—do the plasma p-tau217 levels provide insights into WHEN symptoms might begin? nature.com/articles/s41...

By capturing the balance between aggregate formation and cellular clearance, our model explains decades of stability before sudden runaway dynamics, and offers a framework to predict disease onset and therapeutic efficacy. Mostly driven by Matthew Cotton and Georg Meisl doi.org/10.1063/5.03...

🚨PREPRINT In our new paper, we link RNNs and neural manifolds by introducing the DDM framework. We can train networks to embed an arbitary dynamical system in a latent subspace. We illustrate this with simple models of input-driven and autonomous associative memory. Enjoy! arxiv.org/abs/2602.14885

‼️ New preprint ‼️ How do amyloid-β (Aβ) and tau drive Alzheimer’s disease over time? We introduce a parsimonious, mechanism-based dynamical ATN (dATN) model to simulate longitudinal imaging biomarkers. A short thread 👇 Preprint: www.biorxiv.org/content/10.6...

❗🧠 New review in IEEE RBME How network math models are reshaping how we think about neurodegenerative disease, from brain dynamics to disease progression "Network models of neurodegeneration: bridging neuronal dynamics and disease progression" ieeexplore.ieee.org/document/113...

🚨PREPRINT Coarse-graining diffusions with discrete-state approximations is an easy and effective way to build stochastic models from observed trajectories, but how valid is this approximation? arxiv.org/pdf/2511.05366 We focus on this problem, with an emphasis on the nonequilibrium steady-state.

Our review paper on nonequilibrium physics in the brain is now out in Physics Reports! doi.org/10.1016/j.ph...

How does the 🧠 process information? In this review we show how to use the tools of non-equilibrium thermodynamics to understand brain dynamics in discrete and continuous state spaces Great work led by Ramon as part of his PhD kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...

does brain connectivity drive spread of pathological proteins in Alzheimer’s disease? ✨ preprint: www.biorxiv.org/content/10.1... if the question intrigues you, please read on 🧵⤵️

I'm thrilled that our paper "Personalised regional modelling predicts tau progression in the human brain" is finally published in PLoS Biology! Here's a short thread about the main findings of the paper...

I am so very proud announce my lab's first preprint!! @xiaoyucaly.bsky.social delves into the mechanisms driving tau distribution: * Tau sequence driven by connectivity dynamics * Tau load driven by local factors Check out her thread below

🧠New preprint! What drives tau, the pathological protein in AD, to spread? We found that WHERE tau appears and HOW MUCH accumulates are governed by different mechanisms. Check it out:
www.biorxiv.org/content/10.1...
 #MedSky #neuroskyence #neurosky #alzsky #compneuro #MRI #neuroimaging #neurology

🚨REVIEW We have written a review on the emerging topic of nonequilibrium, irreversible dynamics in the brain. Now out on the arXiv: arxiv.org/abs/2504.12188 We introduce the relevant mathematical frameworks, discuss recent interesting results, and look to the future of this research direction!

Modelling cerebrovascular pathology and the spread of amyloid beta in Alzheimer’s disease: royalsocietypublishing.org/doi/10.1098/... #ProcA #Alzheimers #biophysics

In this paper, we connect local damage to brain vasculature to global progression of toxic proteins leading to neurodegenerative diseases. royalsocietypublishing.org/doi/epdf/10.... We identify situations where disease initiation can be caused by focal hypoperfusion following vascular injury.

🚨PERSPECTIVE We have written a perspective calling for a holistic approach to mathematical modelling for biological systems - it now out on the arXiv: arxiv.org/abs/2503.20511 A thread 🧵

🚨 NEW PAPER ALERT! After such a long journey, I am so glad to see this published in @PNASNews: pnas.org/doi/10.1073/... Big thanks to @leonardobonetti.bsky.social, Gemma Fernandez-Rubio, Peter Vuust, Gustavo Deco, Morten Kringelbach, Renaud Lambiotte and @alaingoriely.bsky.social A thread...

Why academia is sleepwalking into self-destruction. My editorial @brain1878.bsky.social If you agree with the sentiments please repost. It's important for all our sakes to stop the madness academic.oup.com/brain/articl...