The innate immune system must detect viral RNA quickly, while avoiding overreaction to our own RNA. I am delighted to share our work, now published on-line in Molecular Cell: 5′-triphosphate guanosine RNAs recruit GTP-binding proteins to suppress RIG-I/IFN type I signalling.

We are changing the logo, but our scientific excellence remains the same. 👌 IIMCB's new visual identity keeps pace with the changing world. We hope you like this version – clearer, simpler, modern.

A big shout out to the team, Dr Magdalena Wołczyk, Dr Ivan Trus and Jacek Szymański, for all the hard work that went into this achievement. Looking forward to keeping the momentum going and uncovering many more interesting avenues of RNA-protein interactions in innate immunity and beyond.

🌐Our @nature.com paper is out! Researchers from IIMCB and other Polish institutions show how TENT5A boosts mRNA vaccine efficacy by stabilizing therapeutic mRNAs and enhancing antigen production. A step toward better therapies for cancer and beyond! 🧬 👉Read the story: bit.ly/3XYvQkI #Nature #mRNA

👋 Hello BlueSky! We’re the International Institute of Molecular and Cell Biology in Warsaw – a research institute at the forefront of life sciences. Our scientists explore the molecular and cellular mechanisms of life, combining curiosity-driven research with scientific and societal relevance.

TRIM25 takes a centre stage! Right in the context of its RNA-binding role. Exogenous RNA surveillance by proton-sensing TRIM25 | Science www.science.org/doi/abs/10.1...

Dear Polish and European RNA Researchers, Don’t forget to register for the 2nd Polish RNA Biology Meeting in Poznan, June 24-27! 🧬✨ It’s gonna be an incredible event with an AMAZING lineup of keynote speakers already confirmed! 🎉#RNA 👉 Register here: 2ndrna.web.amu.edu.pl

I would like to thank the whole team, especially Nathalie Idlin and Sivakumar Krishnamoorthy (joint first authors) for the great effort! Also, I would like to thank IIMCB www.iimcb.gov.pl/en/, NCN www.ncn.gov.pl and NAWA nawa.gov.pl for their generous support and funding!

RNA-protein interactions were once thought to be undruggable 💊🔬In our latest study, we show how the FDA-approved drug Eltrombopag disrupts HuR/RNA interactions, altering translation, iron metabolism, and hormone levels 🧬 #RNA #Protein #DrugDiscovery bmcbiol.biomedcentral.com/articles/10....

#EmbarrassmentInChief 🤮

Not far away at HHMI. This is how we do it now @hhmi.bsky.social. HHMI Investigator reviews and all competitions consider pre-prints equivalent to peer-reviewed articles. No reason that this can't be the norm everywhere.

In vitro transcription (IVT) is a technology that facilitated the production of mRNA therapeutics and drove numerous breakthroughs in RNA biology. Our new study uncovers unexpected insights into the immunogenicity of in IVT RNAs. #RNA #IVT #Immunity academic.oup.com/nar/advance-...

This is a lovely piece about the 2024 Nobel Prize to Victor Ambros and Gary Ruvkun, written by Bruce Wightman, the first author of one of the prize-winning papers. It emphasizes the importance of fundamental research and the beauty of heterochronic genes. #Celegans #devbio 🧪🧬 doi.org/10.1242/dmm....

I will not even deny it :))) Scholar Goggler

Co wyniknie z dzisiejszego spotkania Komisji Finansów Publicznych? #TakDlaNauki i #TakDlaRozwoju czy trzymanie naszego kraju na poziomie taniej montowni? #NCNtoTlen @dariuszwieczorek.bsky.social @andrzej-domanski.bsky.social @donald-tusk.bsky.social @radek-sikorski.bsky.social

Exciting Opportunity: IIMCB is hiring a Junior Group Leader in Computational Biology to establish an independent research group. Join us in Warsaw!💻 🌍 🔗Full job offer: bit.ly/4fzXJWO #JoinOurTeam #IIMCB #ComputationalBiology #ResearchOpportunity #CareersInScience

🔬🧫 🧬 Are you looking for an opportunity to set up your own laboratory focused on RNA or cell biology in an inspiring environment surrounded by like-minded researchers? The IIMCB in Warsaw is offering an excellent opportunity www.rnasociety.org/junior-group... www.iimcb.gov.pl/en/ #CellBiology #RNA

Hey everyone!